Uploaded October 2021 | Updated September 2026, 2 weeks ago

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The mechanism for an Auwers flavone synthesis which consists of treatment of dibromo-coumarones with alcoholic alkali to give the flavonols. While there is no confirmed mechanism for the Auwers flavone synthesis. The mechanism may involve the nucleophilic addition of oxonium with hydroxide. Base-promoted ring opening could provide the putative intermediate, which then could undergo an intramolecular Michael addition. Removal of the final bromide ion would yield the final product.

Music by Ryan Little
Song: Beach House
Link: youtu.be/xOH9Lbe8gdo