Uploaded March 2026 | Updated September 2026, 2 weeks ago
Neurologist and Alzheimer’s researcher Dr. Dale Bredesen reveals groundbreaking clinical trial results showing that cognitive decline can be prevented — and even reversed — explains why Alzheimer’s may be an “optional” disease, and shares the tests, root causes, and precision-medicine strategies that can dramatically reduce your risk of dementia.
Dr. Dale Bredesen is a neurologist and internationally recognized expert in neurodegenerative diseases, best known for developing a comprehensive, systems-based approach to preventing and reversing cognitive decline. He is the author of multiple bestselling books on Alzheimer’s disease, including The End of Alzheimer’s, and has led decades of research on the molecular mechanisms behind brain aging.
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00:00 — Intro
01:13 — “Alzheimer’s Is Now Optional” — What That Means
03:12 — Inside the New Randomized Controlled Trial
05:16 — Treatment vs Standard Care: Dramatic Results
08:32 — Why This Research Will Face Pushback
12:48 — The Amyloid Theory Controversy & Fraud Claims
17:14 — How to Test Your Alzheimer’s Risk (Blood Test)
21:58 — Why Removing Amyloid Can Be Harmful
27:34 — Alzheimer’s vs Dementia vs Cognitive Decline
35:24 — Brain Fog in Younger People & Long COVID
40:16 — Essential Prevention Tests After 35
46:59 — Insulin Resistance & Brain Metabolism
50:29 — Connection Mode vs Protection Mode
52:33 — Why the Brain “Runs Out of Fuel”
59:48 — Ketones & Cognitive Improvement
01:06:26 — Should You Stay in Ketosis Long-Term?
01:07:31 — Advanced Testing for Memory Problems
01:18:16 — What the Treatment Protocol Includes
01:36:10 — Can Late-Stage Alzheimer’s Improve?
01:37:06 — How Caregivers Can Help
01:48:49 — Message for People Losing Hope
01:52:28 — Future Treatments & Other Brain Diseases
01:54:11 — Final Thoughts
Show notes: jessechappus.com/697
Connect with Dr. Dale Bredesen:
Apollo Health - link.jessechappus.com/29JlrIK
Instagram - link.jessechappus.com/DIjfJHC
Facebook - link.jessechappus.com/D3H3sxY
You can purchase Dr. Bredesen’s books here:
link.jessechappus.com/dr-bredesen-books
Connect with The Jesse Chappus Show:
Website - jessechappus.com
Instagram - instagram.com/jessechappusshow
Disclosure: Some links above may be affiliate links, which means I may earn a commission if you buy through them, at no extra cost to you.
Disclaimer: The opinions expressed in this video are those of the guest and are presented for informational purposes only. This content is not medical advice. Please consult your healthcare provider regarding any health-related decisions.
Neurologist and Alzheimer’s researcher Dr. Dale Bredesen reveals groundbreaking clinical trial results showing that cognitive decline can be prevented — and even reversed — explains why Alzheimer’s may be an “optional” disease, and shares the tests, root causes, and precision-medicine strategies that can dramatically reduce your risk of dementia.
Dr. Dale Bredesen is a neurologist and internationally recognized expert in neurodegenerative diseases, best known for developing a comprehensive, systems-based approach to preventing and reversing cognitive decline. He is the author of multiple bestselling books on Alzheimer’s disease, including The End of Alzheimer’s, and has led decades of research on the molecular mechanisms behind brain aging.
Subscribe to The Jesse Chappus Show on YouTube: youtube.com/@JesseChappus
(And be sure to hit the 🔔 to get notified when new videos are released!)
00:00 — Intro
01:13 — “Alzheimer’s Is Now Optional” — What That Means
03:12 — Inside the New Randomized Controlled Trial
05:16 — Treatment vs Standard Care: Dramatic Results
08:32 — Why This Research Will Face Pushback
12:48 — The Amyloid Theory Controversy & Fraud Claims
17:14 — How to Test Your Alzheimer’s Risk (Blood Test)
21:58 — Why Removing Amyloid Can Be Harmful
27:34 — Alzheimer’s vs Dementia vs Cognitive Decline
35:24 — Brain Fog in Younger People & Long COVID
40:16 — Essential Prevention Tests After 35
46:59 — Insulin Resistance & Brain Metabolism
50:29 — Connection Mode vs Protection Mode
52:33 — Why the Brain “Runs Out of Fuel”
59:48 — Ketones & Cognitive Improvement
01:06:26 — Should You Stay in Ketosis Long-Term?
01:07:31 — Advanced Testing for Memory Problems
01:18:16 — What the Treatment Protocol Includes
01:36:10 — Can Late-Stage Alzheimer’s Improve?
01:37:06 — How Caregivers Can Help
01:48:49 — Message for People Losing Hope
01:52:28 — Future Treatments & Other Brain Diseases
01:54:11 — Final Thoughts
Show notes: jessechappus.com/697
Connect with Dr. Dale Bredesen:
Apollo Health - link.jessechappus.com/29JlrIK
Instagram - link.jessechappus.com/DIjfJHC
Facebook - link.jessechappus.com/D3H3sxY
You can purchase Dr. Bredesen’s books here:
link.jessechappus.com/dr-bredesen-books
Connect with The Jesse Chappus Show:
Website - jessechappus.com
Instagram - instagram.com/jessechappusshow
Disclosure: Some links above may be affiliate links, which means I may earn a commission if you buy through them, at no extra cost to you.
Disclaimer: The opinions expressed in this video are those of the guest and are presented for informational purposes only. This content is not medical advice. Please consult your healthcare provider regarding any health-related decisions.
