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Don’t let their cuteness fool you--these animals are not to be messed with. This week on Reactions we break down the chemistry behind what makes these adorable critters deadly.

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Credits:
Producer: Andrew Sobey
Writer: Samantha Jones, Ph.D.
Scientific Consultants: Leila Duman, Ph.D., Michelle Boucher, Ph.D., Bryan Fry, Ph.D., Diane Brinkman, Ph.D., Katherine Belov, Ph.D., Becky Williams, Ph.D.


Executive Producer: George Zaidan
Production Manager: Hilary Hudson

Music:
Cute
Marc Durst

Night Groove
Gerry Shury, Frank Mc Donald, Chris Rae

Sources:
Slow loris is a venomous animal
ncbi.nlm.nih.gov/pubmed/30764557

Slow loris toxin
ncbi.nlm.nih.gov/pubmed/12590298

Biochemistry, ecology and evolution of slow loris venom
ncbi.nlm.nih.gov/pubmed/24074353

Anaphylactic shock following the bite of a wild Kayan slow loris
ncbi.nlm.nih.gov/pubmed/25309586

Uteroglobin family
ncbi.nlm.nih.gov/pubmed/11193777

Box jelly transcriptome
ncbi.nlm.nih.gov/pubmed/26014501

Box jelly biochemistry
ncbi.nlm.nih.gov/pubmed/19232527

New box jelly venom antidote
nature.com/articles/s41467-019-09681-1

Box jelly venom is hemolytic
ncbi.nlm.nih.gov/pmc/articles/PMC4226504

Tetrodotoxin
ncbi.nlm.nih.gov/pmc/articles/PMC4626696

Tetrodotoxin analogues
ncbi.nlm.nih.gov/pmc/articles/PMC3942760

Cephalopod ink
ncbi.nlm.nih.gov/pmc/articles/PMC4052311

Marine antivenoms
tandfonline.com/doi/abs/10.1081/CLT-120021115

Blue ringed octopus toxicity
ncbi.nlm.nih.gov/pmc/articles/PMC6563023

Tetrodotoxin-producing bacteria
link.springer.com/article/10.1007%2FBF00391147

Venom evolution and identification in the platypus
ncbi.nlm.nih.gov/pmc/articles/PMC4014732

C-type natriuretic peptide
ncbi.nlm.nih.gov/pmc/articles/PMC3605774

Dose and time dependence of box jellyfish antivenom
ncbi.nlm.nih.gov/pmc/articles/PMC4144694

Tetrodotoxin for pain
ncbi.nlm.nih.gov/pmc/articles/PMC3296997

Tetrodotoxin clinical trial
eurekalert.org/pub_releases/2013-06/jtcc-pnm062613.php

Tetrodotoxin levels in pufferfish (Lagocephalus sceleratus) caught in the Northeastern Mediterranean Sea.
ncbi.nlm.nih.gov/pubmed/27211655

Slow loris parasite
ncbi.nlm.nih.gov/pmc/articles/PMC6031959

Spheroidine (Compound)
pubchem.ncbi.nlm.nih.gov/compound/Spheroidine#section=Ecological-Information

Ever wonder why dogs sniff each others' butts? Or how Adderall works? Or whether it's OK to pee in the pool? We've got you covered: Reactions a web series about the chemistry that surrounds you every day.

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World’s Deadliest (& Cutest) Animals @ACSReactions

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