Reactions | How Did We Get COVID Vaccines So Quickly? @ACSReactions | Uploaded 4 years ago | Updated 1 hour ago
You might have heard that vaccine trials are currently underway in Seattle. What exactly is being tested? How much longer will these tests take? And when can we expect a vaccine against the novel coronavirus? We chat with Dr. Benjamin Neuman, one of the world’s experts on coronavirus, and Daniel Wrapp, one of the scientists who mapped the structure of the protein coronavirus uses to infect your cells, to help us answer these questions.
#moderna #vaccine #coronavirus #covid-19 #covid19
Find us on all these places:
Subscribe! http://bit.ly/ACSReactions
Facebook! http://facebook.com/ACSReactions
Twitter! http://twitter.com/ACSReactions
Instagram! instagram.com/acsreactions
Executive Producers:
George Zaidan
Hilary Hudson
Producers:
Andrew Sobey
Elaine Seward
Writer/Host:
Samantha Jones, PhD
Scientific consultants:
Benjamin Neuman, PhD
Daniel Wrapp
Michelle Boucher, PhD
Leila Duman, PhD
Special Thanks:
Ruben Rodriguez
SOURCES:
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
science.sciencemag.org/content/367/6483/1260/tab-figures-data
A Fusion Peptide in the Spike Protein of MERS Coronavirus
ncbi.nlm.nih.gov/pmc/articles/PMC6784214
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
cell.com/cell/pdf/S0092-8674(20)30229-4.pdf
NIH Scientists Identify Atomic Structure of Novel Coronavirus Protein
niaid.nih.gov/news-events/atomic-structure-novel-coronavirus-protein
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
sciencedirect.com/science/article/pii/S0092867420302622
Expression, glycosylation, and modification of the spike (S) glycoprotein of SARS CoV.
ncbi.nlm.nih.gov/pubmed/17502675
Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine
nature.com/articles/s41423-020-0400-4
How SARS hijacks host cells
sciencedaily.com/releases/2013/08/130822122808.htm
Mechanisms of viral assembly
ncbi.nlm.nih.gov/pmc/articles/PMC4382372
Timely development of vaccines against SARS-CoV-2
ncbi.nlm.nih.gov/pubmed/32148172
Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double-Membrane Vesicles
mbio.asm.org/content/4/4/e00524-13
Scientists figure out how new coronavirus breaks into human cells
livescience.com/how-coronavirus-infects-cells.html
A Spotlight on Viruses—Application of Click Chemistry to Visualize Virus-Cell Interactions
mdpi.com/1420-3049/24/3/481/htm
How Viruses Invade Cells
ncbi.nlm.nih.gov/pmc/articles/PMC4788752
The proximal origin of SARS-CoV-2
nature.com/articles/s41591-020-0820-9
Thousands of scientists are racing to find a vaccine for coronavirus. 41 possibilities are in the works
usatoday.com/story/news/2020/03/19/more-than-41-potential-coronavirus-vaccines-works/2870009001
Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1
nejm.org/doi/10.1056/NEJMc2004973
New coronavirus stable for hours on surfaces
nih.gov/news-events/news-releases/new-coronavirus-stable-hours-surfaces
Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents
sciencedirect.com/science/article/pii/S0195670120300463\
Vaccines and Antiviral Drugs in Pandemic Preparedness
ncbi.nlm.nih.gov/pmc/articles/PMC3291404
On the binding affinity of macromolecular interactions: daring to ask why proteins interact
ncbi.nlm.nih.gov/pmc/articles/PMC3565702
Coronavirus envelope protein: current knowledge
virologyj.biomedcentral.com/articles/10.1186/s12985-019-1182-0
First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA
thelancet.com/journals/lancet/article/PIIS0140-6736(20)30607-3/fulltext
The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?
academic.oup.com/ije/advance-article/doi/10.1093/ije/dyaa033/5748175
You might have heard that vaccine trials are currently underway in Seattle. What exactly is being tested? How much longer will these tests take? And when can we expect a vaccine against the novel coronavirus? We chat with Dr. Benjamin Neuman, one of the world’s experts on coronavirus, and Daniel Wrapp, one of the scientists who mapped the structure of the protein coronavirus uses to infect your cells, to help us answer these questions.
#moderna #vaccine #coronavirus #covid-19 #covid19
Find us on all these places:
Subscribe! http://bit.ly/ACSReactions
Facebook! http://facebook.com/ACSReactions
Twitter! http://twitter.com/ACSReactions
Instagram! instagram.com/acsreactions
Executive Producers:
George Zaidan
Hilary Hudson
Producers:
Andrew Sobey
Elaine Seward
Writer/Host:
Samantha Jones, PhD
Scientific consultants:
Benjamin Neuman, PhD
Daniel Wrapp
Michelle Boucher, PhD
Leila Duman, PhD
Special Thanks:
Ruben Rodriguez
SOURCES:
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
science.sciencemag.org/content/367/6483/1260/tab-figures-data
A Fusion Peptide in the Spike Protein of MERS Coronavirus
ncbi.nlm.nih.gov/pmc/articles/PMC6784214
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
cell.com/cell/pdf/S0092-8674(20)30229-4.pdf
NIH Scientists Identify Atomic Structure of Novel Coronavirus Protein
niaid.nih.gov/news-events/atomic-structure-novel-coronavirus-protein
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
sciencedirect.com/science/article/pii/S0092867420302622
Expression, glycosylation, and modification of the spike (S) glycoprotein of SARS CoV.
ncbi.nlm.nih.gov/pubmed/17502675
Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine
nature.com/articles/s41423-020-0400-4
How SARS hijacks host cells
sciencedaily.com/releases/2013/08/130822122808.htm
Mechanisms of viral assembly
ncbi.nlm.nih.gov/pmc/articles/PMC4382372
Timely development of vaccines against SARS-CoV-2
ncbi.nlm.nih.gov/pubmed/32148172
Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double-Membrane Vesicles
mbio.asm.org/content/4/4/e00524-13
Scientists figure out how new coronavirus breaks into human cells
livescience.com/how-coronavirus-infects-cells.html
A Spotlight on Viruses—Application of Click Chemistry to Visualize Virus-Cell Interactions
mdpi.com/1420-3049/24/3/481/htm
How Viruses Invade Cells
ncbi.nlm.nih.gov/pmc/articles/PMC4788752
The proximal origin of SARS-CoV-2
nature.com/articles/s41591-020-0820-9
Thousands of scientists are racing to find a vaccine for coronavirus. 41 possibilities are in the works
usatoday.com/story/news/2020/03/19/more-than-41-potential-coronavirus-vaccines-works/2870009001
Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1
nejm.org/doi/10.1056/NEJMc2004973
New coronavirus stable for hours on surfaces
nih.gov/news-events/news-releases/new-coronavirus-stable-hours-surfaces
Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents
sciencedirect.com/science/article/pii/S0195670120300463\
Vaccines and Antiviral Drugs in Pandemic Preparedness
ncbi.nlm.nih.gov/pmc/articles/PMC3291404
On the binding affinity of macromolecular interactions: daring to ask why proteins interact
ncbi.nlm.nih.gov/pmc/articles/PMC3565702
Coronavirus envelope protein: current knowledge
virologyj.biomedcentral.com/articles/10.1186/s12985-019-1182-0
First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA
thelancet.com/journals/lancet/article/PIIS0140-6736(20)30607-3/fulltext
The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?
academic.oup.com/ije/advance-article/doi/10.1093/ije/dyaa033/5748175
