Uploaded February 2026 | Updated September 2026, 2 weeks ago
Here, I explain how intermittent fasting differs from time-restricted eating, where the research comes from, and why that matters for active midlife women. This clip explores why exercise delivers stronger signals for health and longevity than fasting, and how female physiology-XX genetics, higher mitochondrial density and antioxidant capacity, and two nutrient-sensitive kisspeptin centers in the hypothalamus - changes our response to low energy availability. I talk through what happens when women train fasted or restrict carbohydrates: kisspeptin downregulation, appetite hormone disruption, a reduced LH pulse, and knock-on effects for the menstrual cycle.
I also outline why active women perform better in a fed state, how women’s fuel use in training differs from men’s, and why eating with circadian rhythm-fuel during the day, stop around 7-8 pm, breakfast the next morning often works better than rigid fasting windows. The common fasting benefits you hear about (glucose control, autophagy, cognition) are largely from male data and aren’t seen in female data.
Watch the full episode here: youtube.com/watch?v=mvwJENne-n4
Want to go deeper? Start here:
Menopause 2.0
Your complete science-based guide to training through midlife and beyond
👉 drstacysims.com/menopause?utm_source=feb26wk4s&utm_medium=social&utm_campaign=youtube
Microlearning Courses
Focused courses on supplements, hormones, and training - each under 3 hours
👉 drstacysims.com/microlearning?utm_source=feb26wk4s&utm_medium=social&utm_campaign=youtube
Next Gen: Training Active Girls
For coaches, parents & teachers helping girls thrive through puberty and sport
👉 drstacysims.com/nextgen?utm_source=feb26wk4s&utm_medium=social&utm_campaign=youtube
Not sure where to start. Start here:
👉 drstacysims.com/product_guide?utm_source=feb26wk4s&utm_medium=social&utm_campaign=youtube
▶️ Watch Next:
Continue learning with these related videos:
The Truth About Women’s Training & Nutrition | Dr. Stacy Sims on Andrew Huberman Podcast
youtu.be/CYew_LtZt4I?si=DV3vpzKX7qcVuyWs
Is Mainstream Exercise Advice Sexist? Here’s the Truth! | Dr. Stacy Sims on Diary of a CEO
youtu.be/-4I0U9ApVEw?si=u1CsDLVaAG_SzMOi
Why Women Need a Different Approach to Nutrition & Training | Dr Stacy Sims on The Proof
youtu.be/4c7udsxd3c8?si=wG8wZTmE4s36xA9G
👩🔬 About Me:
I’m Dr. Stacy Sims, exercise physiologist, nutrition scientist, and author of ROAR and Next Level. My mission is simple: stop training women like small men. I help you understand and work with your physiology - for better performance, health, and longevity.
📩 Join my newsletter for updates, tips, and free resources
👉 drstacysims.com/generic_optin
Follow me for daily tips:
Instagram: @drstacysims
Facebook: @drstacysims
LinkedIn: Dr. Stacy Sims
🔔 Subscribe for new videos on women's health, training, and recovery
👍 Like, share, and drop a comment - I love hearing your questions
#DrStacySims #WomenAreNotSmallMen #WomensHealth #FemaleAthletes #ExerciseScience #Hormones #StrengthTraining #MenopauseFitness
Here, I explain how intermittent fasting differs from time-restricted eating, where the research comes from, and why that matters for active midlife women. This clip explores why exercise delivers stronger signals for health and longevity than fasting, and how female physiology-XX genetics, higher mitochondrial density and antioxidant capacity, and two nutrient-sensitive kisspeptin centers in the hypothalamus - changes our response to low energy availability. I talk through what happens when women train fasted or restrict carbohydrates: kisspeptin downregulation, appetite hormone disruption, a reduced LH pulse, and knock-on effects for the menstrual cycle.
I also outline why active women perform better in a fed state, how women’s fuel use in training differs from men’s, and why eating with circadian rhythm-fuel during the day, stop around 7-8 pm, breakfast the next morning often works better than rigid fasting windows. The common fasting benefits you hear about (glucose control, autophagy, cognition) are largely from male data and aren’t seen in female data.
Watch the full episode here: youtube.com/watch?v=mvwJENne-n4
Want to go deeper? Start here:
Menopause 2.0
Your complete science-based guide to training through midlife and beyond
👉 drstacysims.com/menopause?utm_source=feb26wk4s&utm_medium=social&utm_campaign=youtube
Microlearning Courses
Focused courses on supplements, hormones, and training - each under 3 hours
👉 drstacysims.com/microlearning?utm_source=feb26wk4s&utm_medium=social&utm_campaign=youtube
Next Gen: Training Active Girls
For coaches, parents & teachers helping girls thrive through puberty and sport
👉 drstacysims.com/nextgen?utm_source=feb26wk4s&utm_medium=social&utm_campaign=youtube
Not sure where to start. Start here:
👉 drstacysims.com/product_guide?utm_source=feb26wk4s&utm_medium=social&utm_campaign=youtube
▶️ Watch Next:
Continue learning with these related videos:
The Truth About Women’s Training & Nutrition | Dr. Stacy Sims on Andrew Huberman Podcast
youtu.be/CYew_LtZt4I?si=DV3vpzKX7qcVuyWs
Is Mainstream Exercise Advice Sexist? Here’s the Truth! | Dr. Stacy Sims on Diary of a CEO
youtu.be/-4I0U9ApVEw?si=u1CsDLVaAG_SzMOi
Why Women Need a Different Approach to Nutrition & Training | Dr Stacy Sims on The Proof
youtu.be/4c7udsxd3c8?si=wG8wZTmE4s36xA9G
👩🔬 About Me:
I’m Dr. Stacy Sims, exercise physiologist, nutrition scientist, and author of ROAR and Next Level. My mission is simple: stop training women like small men. I help you understand and work with your physiology - for better performance, health, and longevity.
📩 Join my newsletter for updates, tips, and free resources
👉 drstacysims.com/generic_optin
Follow me for daily tips:
Instagram: @drstacysims
Facebook: @drstacysims
LinkedIn: Dr. Stacy Sims
🔔 Subscribe for new videos on women's health, training, and recovery
👍 Like, share, and drop a comment - I love hearing your questions
#DrStacySims #WomenAreNotSmallMen #WomensHealth #FemaleAthletes #ExerciseScience #Hormones #StrengthTraining #MenopauseFitness
