Train Like a Woman: An interview with Dr. Stacy Sims, author of ROAR InsideTracker 2026-09-25 | Train Like a Woman: An interview with Dr. Stacy Sims, author of ROAR
Dr. Peter Fedichev: Why Aging Is Functional Decline, Not Just Disease InsideTracker 2025-09-17 | Aging is more than disease—it’s the steady decline of function. In this episode of Longevity by Design, Dr. Gil Blander speaks with physicist-turned-biotech innovator Dr. Peter Fedichev about why resilience, not diseases, holds the key to longer lives.Peter explains how his background in theoretical physics shaped his approach to biology and aging. He outlines why startups, not large institutions, are now leading innovation in longevity science. Drawing from physics, he describes aging as a series of “jumps” between states, each leaving the body more fragile.The discussion moves from the limits of current drugs to the promise of new approaches. Peter argues that reducing fluctuations and increasing molecular fidelity could unlock far greater gains in healthspan and lifespan. Listeners gain a fresh lens on what drives aging, where the real breakthroughs may come from, and why the next frontier in longevity will require rethinking the problem altogether.Guest-at-a-Glance💡 Name: Peter Fedichev💡 What they do: Founder & CEO💡 Company: Gero (biotech company using AI to study aging)💡 Noteworthy: Physicist turned biotech leader applying statistical physics to model biological age and resilience💡 Where to find them: LinkedInEpisode highlights:[00:00:00] Opening Thoughts on Venture Capital[00:00:58] Host Introduction and Show Welcome[00:01:25] Guest Background: From Physics to Biotech[00:02:42] Physics as a Tool for Biology[00:05:19] Why Switch From Physics to Biology[00:06:20] Discovering Aging Through Naked Mole Rats[00:09:27] Defining Professional Goal in Aging[00:10:15] Challenges in Crossing Disciplines[00:11:58] Startups Driving Scientific Innovation[00:14:09] Pharma, Biotech, and Market Dynamics[00:16:23] Aging as a System-Level Problem[00:18:56] Drugs With Modest Longevity Effects[00:20:14] Aging vs. Disease: Functional Decline[00:23:48] Squaring the Curve vs. True Aging[00:26:02] Sponsor Message: InsideTracker[00:26:56] Resilience in 90-Year-Olds[00:27:55] Measuring Health With Longitudinal Data[00:30:07] Aging as Jumps Between States[00:31:49] Declining Recovery Times With Age[00:33:33] Cancer Risk and Immune Decline[00:34:30] Rare Events Driving Aging Jumps[00:36:15] Mutations, Epimutations, and Reliability Theory[00:38:31] Perfect Storm Failures in Aging[00:40:26] Cancer, Diabetes, and System Crashes[00:42:09] Searching for a Master Switch[00:43:41] Reducing Physiological Noise to Slow Aging[00:45:54] Targeting Fluctuations as Drug Strategy[00:47:13] Stress, Hormesis, and Adaptation[00:49:27] Evolutionary Role of Stress Responses[00:50:58] Model Organisms: Mice vs. Dogs[00:53:41] Why Dogs Mirror Human Aging[00:55:42] Regulatory Edge: Aging Trials in Dogs[00:56:42] Next-Gen Drugs Beyond GLP-1[00:58:22] Epigenetic Rejuvenation vs. Noise Control[01:00:11] Key Targets: Chromatin Modifiers[01:01:10] Measuring Fluctuations With Biomarkers[01:02:58] Dogs as Proof-of-Concept Model[01:03:23] Defining Jumps Through Omics DataWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
Dr. Eric Verdin on the Effects of Therapeutic Plasma Exchange on Longevity InsideTracker 2025-09-03 | In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Eric Verdin, President and CEO of the Buck Institute for Research on Aging. Eric discusses the science behind therapeutic plasma exchange (TPE) and its potential to slow biological aging in humans. The conversation explores findings from a recent clinical trial, including measurable age reversal using epigenetic clocks.Eric explains how removing and replacing plasma can dilute pro-aging factors in the blood, a concept inspired by earlier animal studies on parabiosis. He also describes why rigorous, placebo-controlled human trials are crucial for validating longevity interventions and distinguishing the field from hype-driven wellness trends.The episode also highlights how omics data, such as metabolomics and proteomics, are shaping a new era of precision aging research. Eric emphasizes the value of lifestyle interventions as a foundation and sees future opportunities in combining TPE with personalized strategies to extend healthspan.Guest-at-a-Glance💡 Name: Dr. Eric Verdin💡 What they do: President and CEO💡 Company: Buck Institute for Research on Aging💡 Noteworthy: Physician-scientist pioneering human aging research through epigenetics, metabolism, and translational science.💡 Where to find him: LinkedInEpisode highlights:[00:00:00] Introduction to Longevity and Healthspan[00:01:07] Meet Dr. Eric Verde: A Pioneer in Aging Research[00:02:24] Exploring Therapeutic Plasma Exchange[00:03:08] The Science Behind Heterochronic Parabiosis[00:07:17] Clinical Trials and Methodologies[00:12:58] The Role of Omics in Precision Medicine[00:17:20] Epigenetic Clocks and Aging[00:22:04] Therapeutic Plasma Exchange: Results and Implications[00:26:22] Exploring Frequency and Efficacy of Treatments[00:28:23] Biomarkers and Predictive Models[00:31:33] Safety Profile and Side Effects[00:33:28] Intrinsic Capacity and Aging Metrics[00:36:58] Combining Treatments with Lifestyle Changes[00:44:26] Future Directions and Recommendations[00:49:08] Conclusion and Final ThoughtsWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
What Happens to Your Body When You Sit All Day, with Dr. Keith Diaz InsideTracker 2025-08-20 | In this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Keith Diaz, Associate Professor of Behavioral Medicine at Columbia University Irving Medical Center, to unpack the hidden health risks of prolonged sitting.Keith explains why even daily exercise isn't enough to counteract the effects of sedentary behavior. Drawing on his lab's findings, he shares a simple but powerful prescription: five minutes of light walking every hour. That small change can lower blood pressure, improve mood, and reduce fatigue, without needing to break a sweat.The conversation also explores how modern work and home environments are built around sitting, and what it takes to build smarter habits. From treadmill desks to family walks, Keith offers practical strategies that make movement part of everyday life. Whether you're an employer, a clinician, or just desk-bound, this episode helps you rethink how you move through your day.Guest-at-a-Glance💡 Name: Dr. Keith Diaz💡 What they do: Associate Professor💡 Company: Columbia University Irving Medical Center💡 Noteworthy: Leading researcher on sedentary behavior, cardiovascular health, and wearable tech in clinical care.💡 Where to find them: LinkedInEpisode highlights:[00:00:00] Introduction: The Evolution of Television Viewing Habits[00:00:23] Welcome to Longevity By Design[00:00:33] Introducing Dr. Ki Diaz[00:02:14] The Impact of Sedentary Behavior[00:04:23] The Physiology of Sitting[00:09:59] Exercise vs. Sedentary Lifestyle[00:16:56] Movement Breaks: How Short is Beneficial?[00:27:45] The Role of Wearable Devices[00:31:51] Integrating Movement into Daily Routines[00:33:34] Behavioral Changes and Personal Strategies[00:34:55] The Benefits of Movement Breaks at Work[00:37:26] Wearables and Their Impact on Health[00:40:16] Clinicians' Role in Promoting Movement[00:43:09] Tailoring Movement to Individual Lifestyles[00:47:28] Incentives for Employers and Insurers[00:52:46] Personal Movement Hacks and Daily Routines[00:58:16] Future Research and Final ThoughtsWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
Acetylation Insights: Unlocking Longevity Secrets with Dr. Haim Cohen InsideTracker 2025-08-06 | In this episode, Dr. Gil Blander welcomes Dr. Haim Cohen to Longevity by Design to explore his revolutionary approach to understanding aging. Haim's team analyzed acetylation sites across 107 mammalian species, creating its most extensive comparative study. This computational approach revealed specific post-translational modifications that evolved exclusively in long-lived animals.The research identifies critical pathways where evolution engineered longevity solutions. These acetylation changes affect DNA repair, cell cycle regulation, and mitochondrial function. Unlike traditional aging research focusing on single pathways like mTOR or caloric restriction, Haim's unbiased screening simultaneously reveals multiple longevity targets. Evolution provided a natural laboratory for testing anti-aging modifications over millions of years.The findings offer exciting therapeutic possibilities for human longevity. Haim's team is now creating transgenic mice to test whether mimicking these evolutionary changes can extend lifespan in the lab. This research suggests humans could potentially "accelerate evolution" by implementing modifications that nature has already proven effective in whales, elephants, and other long-lived species.Guest-at-a-Glance💡 Name: Dr. Haim Cohen 💡 What they do: Professor of Molecular Genetics focused on the biology of aging 💡 Institution(s): Bar-Ilan University (Israel); Founder & Director, Minerva Israel-Germany Center forBiological Mechanisms of Aging; Founder & Director, Sagol Center for Human Health and Longevity 💡 Noteworthy: Global leader in aging research; author of 75+ peer-reviewed papers, including work showing SIRT6 over-expression can extend mouse lifespan by ~30 percent 💡 Where to find them: Bar-Ilan University faculty pageEpisode highlights:[00:00:00] Introduction[00:01:00] Dr. Haim Cohen background and SIRT6 research update[00:05:50] Gender-specific effects in aging research[00:07:40] Introduction to the groundbreaking Nature paper on acetylation[00:08:30] What is acetylation and why study it[00:11:40] Study design across 107 mammalian species[00:15:00] Using evolution as a research laboratory[00:19:00] Key findings and statistical approach[00:28:00] Validating specific proteins - CBS and hydrogen sulfide[00:31:30] Mitochondrial acetylation and metabolism[00:34:10] DNA repair pathways and the Peto Paradox[00:35:00] Cancer prevention mechanisms in large animals[00:38:30] P53 tumor suppressor conservation[00:40:50] Cat family longevity anomaly[00:42:10] Therapeutic implications and drug development[00:45:00] Targeting proteins versus modifications[00:47:40] Study limitations and future validation[00:49:20] Comparing effects to existing longevity interventions[00:51:00] Implications for human longevity[00:55:00] Dr. Cohen's top tip for longevityWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
Karl Pfleger Explains the Aging Biotech Explosion InsideTracker 2025-07-23 | On this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Karl Pfleger, aging biotechnology investor and creator of AgingBiotech.info, to dissect the rapidly evolving field of aging therapeutics. Karl breaks down the sector into two main categories: interventions that slow aging rates versus rejuvenation strategies that repair accumulated damage.Karl highlights the most promising areas in his investment portfolio, including senolytics for clearing senescent cells and epigenetic reprogramming technologies. He explains why current aging clocks aren't ready for clinical use and discusses the limitations of popular interventions like GLP-1 drugs and fasting protocols. The conversation reveals that 14 Phase 3 clinical trials are currently testing core aging therapeutics.The discussion covers recent FDA approvals for ATTR treatments and stem cell therapies, signaling the field's maturation. Karl emphasizes that meaningful life extension requires a "divide and conquer" strategy, targeting multiple aging mechanisms simultaneously rather than relying on single interventions. Despite exciting therapeutic developments, he maintains that optimizing diet, exercise, and sleep remains the most impactful strategy for extending healthspan today.Guest-at-a-Glance💡 Name: Dr. Karl Pfleger💡 What they do: Angel investor, philanthropist, and advocate in aging and longevity biotechnology💡 Institution(s): Creator and maintainer of AgingBiotech.info (comprehensive public database of 400+ aging companies)💡 Noteworthy: Exclusively invests in aging/longevity sector with 15+ portfolio companies targeting damage repair approaches💡 Where to find them: LinkedIn | AgingBiotech.info | X (Twitter)Episode highlights:00:00:00 Introduction to GLP-1 Drugs and Their Impact00:00:56 Meet Dr. Karl Pfleger: A Pioneer in Aging and Longevity00:02:50 Karl Pfleger's Journey from Tech to Aging Biology00:05:18 The Current State of Longevity Biotech00:09:47 Exciting Developments in Rejuvenation Biotechnology00:24:17 Aging Biotech Info: A Comprehensive Resource00:31:59 Future Plans for Aging Biotech Info00:36:51 The Obesity Revolution: GLP-1 Receptor Agonists00:40:29 Global Obesity Rates and GLP-1 Drugs00:40:43 Potential Benefits and Limitations of GLP-1 Drugs00:42:13 Muscle Atrophy and Side Effects of GLP-1 Drugs00:44:12 Emerging Muscle Aging Treatments00:46:10 Biotech Companies and Obesity Programs00:46:53 Public vs. Private Biotech Companies00:49:12 Fasting and Calorie Restriction00:55:20 Blood Transfusions and Parabiosis00:58:09 Metformin and N-of-1 Experiments00:59:13 Comprehensive Aging Interventions01:03:54 Diagnostics and Aging Clocks01:13:49 Future of Aging Interventions01:16:07 Top Tips for Health and LongevityWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
How to Extend Your Healthspan with Dr. Eric Topol InsideTracker 2025-07-09 | Gil and Eric discuss Eric’s book, Super Agers, and the inspiration behind it: a 98-year-old patient who exemplified healthy aging. They explore the five dimensions of healthspan optimization: lifestyle, omics, the immune system, and the role of data and AI in personalized medicine. Eric highlights how AI can analyze multi-layered data to provide personalized recommendations for preventing age-related diseases.The conversation also explores the importance of exercise, sleep, and social connection for healthy aging, as well as the risks associated with high-dose statins. Eric emphasizes the need for a shift towards preventative care, using data and AI to identify and address individual risks. He stresses the power of lifestyle changes, rather than supplements, in improving long-term health outcomes.Guest-at-a-Glance💡 Name: Dr. Eric Topol 💡What they do: Founder and Director 💡Company: Scripps Research Translational Institute💡Noteworthy: Genomics pioneer, digital medicine innovator, and preventative care advocateEpisode highlights:[00:00:00] The Impact of Social Isolation on Health[00:01:19] Meet Dr. Eric Topol: A Pioneer in Medicine[00:03:16] Dr. Topol's Personal Journey into Medicine[00:05:31] The Early Days of Genetic Therapy[00:07:54] Insights from Dr. Topol's Book: Super Agile[00:13:02] The Role of Genetics in Longevity[00:14:22] The Five Dimensions of Healthspan[00:20:08] The Power of Exercise and Diet[00:23:58] The Truth About Supplements[00:32:38] The Importance of Sleep[00:36:07] The Value of Social Relationships[00:38:02] The Benefits of Nature and Social Interaction[00:39:17] Exploring Longevity Drugs: Metformin and Rapamycin[00:40:10] Risks and Benefits of Longevity Treatments[00:41:56] The Potential of GLP-1 Drugs[00:46:41] Statins and Their Impact on Health[00:51:11] Emerging Cancer Detection Technologies[00:56:15] The Role of AI and Polygenic Scores in Healthcare[00:57:36] Preventing Alzheimer's Disease[01:01:14] The Future of Longevity and HealthspanWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
The Science of Muscle, Protein, and Longevity: Insights from Dr. Layne Norton InsideTracker 2025-06-18 | In this episode of Longevity By Design, Dr. Layne Norton (@biolayne1), Founder of BioLayne and Carbon app, joins Gil Blander to discuss optimizing nutrition and fitness for a longer, healthier life. Layne emphasizes the importance of prioritizing scientific evidence over popular narratives, highlighting how easily isolated studies can be misinterpreted. He stresses the power of personalized approaches to nutrition and fitness, advocating for a critical approach to information consumption.Layne dives into the complexities of protein intake, challenging common misconceptions. He advocates for a protein intake above the recommended daily allowance, stressing the role of muscle mass in overall health and longevity. Layne explains the importance of resistance training, even for older adults, to maintain muscle mass and reduce fall risk. He advocates for finding enjoyment in exercise, stressing that passion fuels consistency.Beyond physical health, Layne underscores the impact of mental health on longevity. He discusses the detrimental effects of stress, provides practical stress management tips, and encourages healthy boundaries. Layne’s holistic approach highlights lifestyle factors, nutrition, training, and stress management , as key drivers of a longer, healthier lifespan.Episode highlights:[00:00:52] Introduction to Longevity By Design[00:01:03] Meet Dr. Layne Norton[00:02:00] Layne's Academic Journey[00:03:48] Choosing the Right Advisor[00:06:56] The Importance of Critical Analysis in Research[00:10:00] Transitioning from Academia to Public Communication[00:11:29] The Role of Social Media in Science Communication[00:13:33] Launching a Podcast and Future Plans[00:17:09] Understanding Risk and Misconceptions in Health[00:22:59] The Importance of Protein in Aging[00:41:50] Protein Consumption for Non-Daily Lifters[00:43:07] Debunking the Protein Timing Myth[00:45:31] Protein Distribution and Muscle Growth[00:50:09] Resistance Training for Older Adults[00:53:45] The Importance of Recovery and Sleep[00:56:15] Managing Psychological Stress[01:01:31] Wearable Data and Subjective Feelings[01:04:42] The Impact of GLP-1 Agonists on Weight Loss[01:09:47] Supplements for Health and Longevity[01:13:32] AI in Health and Wellness[01:14:46] Advice for Different Life Stages[01:17:45] Top Tips for Health and LongevityWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
Beyond Sick Care: Evelyne Bischof on the Rise of Longevity Medicine InsideTracker 2025-06-04 | On this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Evelyne Bischof, President of the Healthy Longevity Medicine Society. Evelyne discusses her background in internal medicine and oncology and how her work puzzling together patient diagnoses led her to the field of longevity medicine. She highlights the importance of optimizing health span, not just lifespan, and how healthy longevity medicine benefits not only individuals, but population health and the world economy as well.Gil and Evelyne explore the difference between longevity medicine and traditional healthcare. Evelyne explains that longevity medicine uses a broader range of diagnostics, including advanced biomarkers, imaging, and cognitive tests. This approach aims to build a personalized health trajectory for each patient. They also discuss the role of AI in healthcare, with Evelyne expressing hope for faster, AI-driven diagnostics and drug discovery in the future.Finally, they touch upon the Healthy Longevity Medicine Society, its mission to establish longevity medicine as a recognized medical discipline, and the exciting developments in the field, such as the SHARP study at the Sheba Longevity Center. Evelyne emphasizes the importance of being data-driven and encourages listeners to collect and track their own health data. She believes this empowers individuals to make informed decisions about their health and longevity.Episode highlights:[00:01:24] Meet Dr. Evelyne Bischof[00:05:12] The Concept of Longevity Medicine[00:08:42] Health Span vs. Lifespan[00:11:39] The Role of Diagnostics in Longevity Medicine[00:22:54] Global Landscape of Longevity Medicine[00:29:50] Collaborations and Growth Initiatives[00:30:30] Monthly Case Studies and Activities[00:31:27] Membership and Target Audience[00:34:42] Organizational Structure and Leadership[00:39:52] Shiba Longevity Center Overview[00:45:22] Future of Longevity Medicine[00:50:27] Top Healthspan Tips and Final ThoughtsLongevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit https://hubs.li/Q02BxrGL0 for 10% off any InsideTracker plan.
How Wearables and AI Are Powering Personalized Longevity with Dr Renee Deehan and Paul Fabian InsideTracker 2025-05-21 | In this episode of Longevity by Design, our host, Dr. Gil Blander, talks with Dr. Renee Deehan and Paul Fabian about Inside Tracker's new Healthspan Habits Score feature. This innovative tool analyzes data from wearable devices and daily journal entries to identify the most impactful habit to improve each week for better health span and longevity.The guests explain how the algorithm processes up to 15 different variables, including sleep quality, step count, and lifestyle factors, to create a personalized weekly score. Rather than overwhelming users with multiple recommendations, the report focuses on one key habit to change, applying behavioral science principles for sustainable improvement.Deehan and Fabian detail how the system evaluates six weeks of data to identify trends and provide targeted recommendations, helping users bridge the gap between blood tests with actionable weekly guidance based on scientific research linking these habits to longevity outcomes.Episode highlights:Introduction to Healthspan and Lifespan 00:00:00Meet the Experts: Dr. Renee Dhan and Paul Fabian 00:01:07Paul Fabian's Journey to Science 00:03:24Introducing the Health Span Habits Core Tool 00:04:31Inspiration Behind the Health Span Habits Core 00:05:07How the Health Span Habits Core Works 00:06:40Personalized Health Recommendations 00:08:02How does Insight Tracker turn intent into action 00:10:16How the Health Span Habit Score is Calculated 00:13:25The Importance of Bedtime Consistency 00:22:00Behavioral Science in Health Tracking 00:25:35User Feedback and Future Directions 00:31:38Final Thoughts and Tips for Longevity 00:42:20 Guest-at-a-Glance 💡 Name: Dr. Renee Deehan 💡 What she does: Senior Vice President of Science and Artificial Intelligence 💡 Company: InsideTracker 💡 Noteworthy: Expert in precision health with a PhD from UC Berkeley 💡 Where to find her: LinkedIn, linkedin.com/in/ren%C3%A9e-deehan-747b471Guest-at-a-Glance 💡 Name: Paul Fabian 💡 What he does: Researcher 💡 Company: InsideTracker 💡 Noteworthy: Specializes in genetics, exercise biomarkers, and data-driven health recommendations 💡 Where to find him: LinkedIn, linkedin.com/in/paul-fabianWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
Scanning the Future: How Whole-Body MRI is Transforming Longevity with Dr. Daniel Durand InsideTracker 2025-05-20 | Dr. Gil Blander welcomes Dr. Daniel Durand, Chief Medical Officer at Prenuvo, to Longevity by Design for a deep dive into the future of preventative healthcare. Dr. Durand shares how full-body MRI is redefining early detection by making advanced imaging accessible, non-invasive, and radiation-free. He explains why MRI, as a soft tissue imaging modality, offers unmatched insight into early-stage cancers and chronic conditions.The conversation unpacks misconceptions around overdiagnosis and false positives, challenging the idea that “not knowing” is safer. Dr. Durand outlines how AI-enhanced imaging, paired with structured follow-up care, reduces unnecessary biopsies and improves diagnostic accuracy. He also discusses the emotional and systemic costs and benefits of proactive screening.Looking ahead, Dr. Durand envisions a healthcare model built on data, personalization, and patient empowerment. He argues that gathering better information, earlier, will shift the focus from treatment to prevention and help more people maintain peak health for longer.Guest-at-a-Glance💡 Name: Dr. Daniel Durand💡What he does: Chief Medical Officer💡Company: Prenuvo💡Noteworthy: Leader in radiology innovation and early detection through full-body MRI.💡 Where to find him: linkedin.com/in/daniel-j-durand-151a0836 Episode highlights:Introduction to MRI and Its Advancements 00:00:00Welcome and Guest Introduction 00:00:59 Dr. Durand's Career Journey 00:02:07 Choosing Radiology and MRI 00:03:09The Future of Radiology and AI 00:04:48Early Detection and Preventative Health 00:11:21The Patient Experience at Pvo 00:29:27Capabilities and Benefits of MRI 00:35:47Liquid Biopsy vs. Whole Body MRI 00:44:00Combining Diagnostic Methods 00:46:31Colonoscopy and MRI: Complementary Tools 00:48:30 Risks and Benefits of Full Body MRI 00:51:28Addressing Concerns and Criticisms 00:54:37Patient Empowerment and the Future of Diagnostics 00:55:44Emotional Impact of Diagnostic Information 00:57:00 Consultation and Communication with Patients 01:01:14 Technological Innovations in MRI 01:05:07Target Audience for Full Body MRI 01:10:52Future of Healthspan and Longevity 01:16:18We Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
AI, LLMs & The Future of Longevity: Unlocking Healthspan Innovations with Dr. Eran Segal InsideTracker 2025-04-16 | In this episode of Longevity by Design, host Dr. Gil Blander welcomes Dr. Eran Segal, Professor at the Weizmann Institute of Science, to explore the intersection of artificial intelligence (AI) and personalized health. The conversation dives into how AI and machine learning are transforming our understanding of nutrition, disease prediction, and overall longevity. Eran provides a clear overview of AI, machine learning, and deep learning, explaining how these technologies can be applied to various health domains.Eran discusses the potential of AI agents in healthcare, such as scheduling appointments, managing medications, and even creating personalized dietary recommendations. He highlights the importance of data in training AI models, noting that the healthcare industry lags behind in publicly available and diverse data sets. The 10K Initiative, a project Eran leads, aims to address this issue by collecting comprehensive data on individuals to build more holistic AI models for personalized health.Gil and Eran consider the future, envisioning AI-powered digital twins that can simulate the impact of lifestyle changes on disease development. While AI offers exciting possibilities, Eran cautions against over-reliance, emphasizing the need for continued human oversight and validation. He reiterates that the foundation of longevity still relies on simple habits: sleep well, eat well, and exercise regularly.Guest-at-a-Glance💡 Name: Dr. Eran Segal 💡What they do: Professor 💡Company: Weizmann Institute of Science💡Noteworthy: Computional biologist revolutionizing precision medicine with AI and personalized nutrition.💡 Where to find them: LinkedIn Episode highlights:Meet Dr. Eran Sega: 00:01:19Eran's Journey to Becoming a Scientist: 00:02:25Understanding Personalized Nutrition: 00:04:40The Link Between Nutrition and Longevity: 00:07:02Introduction to AI and Machine Learning: 00:08:07Deep Learning and Generative Models Explained: 00:10:09The Revolution of Large Language Models (LLMs): 00:13:42Practical Use Cases of AI Tools: 00: 19:12The Future of Programming with AI: 00:23:54The Rise of AI Agents: 00:28:20AI in Health and Wellness: 00:29:27Exploring the Best Uses of LLM and ChatGPT: 00:33:23Real-World Examples of LLM Applications: 00:34:23Limitations and Risks of LLM Technology: 00: 36:08Comparing ChatGPT with Other LLM Tools: 00:39:01Generative AI in Healthcare: Applications and Limitations: 00:39:57The 10K Initiative: Revolutionizing Health Data: 00:45:31Future Applications of LLM in Personalized Health: 00:49:19Looking Ahead: The Future of AI and Healthcare: 00:56:11Key Takeaways for Health and Longevity: 00:58:10Longevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit https://hubs.li/Q021Z4gp0 for 20% off any InsideTracker plan.
GLP-1, Wearables & Longevity: What You Need to Know – AMA with Gil & Ashley InsideTracker 2025-04-02 | Dr. Gil Blander and Ashley Reaver dive into the science behind GLP-1 agonists, a class of drugs originally developed for type 2 diabetes but now widely used for weight management and longevity. They explore how these medications work, their effects on appetite, metabolism, and inflammation, and why they might be a game-changer for cardiovascular health, brain function, and fertility. While promising, they emphasize the importance of long-term research and consulting with medical professionals before considering these treatments.The conversation shifts to the role of wearables in health tracking. Gil shares insights on devices like the Apple Watch, Oura Ring, and Whoop, highlighting their capabilities in tracking sleep, fitness, illness detection, and fall prevention—especially for older adults. They break down how different wearables cater to specific needs and the future of personalized health monitoring.As the science of longevity evolves, Gil and Ashley stress the importance of staying informed, making data-driven decisions, and using technology wisely. Whether through cutting-edge pharmaceuticals or smart wearables, optimizing health is now more accessible than ever.Host-at-a-Glance💡 Name: Gil Blander 💡What he does: Founder and CSO💡Company: InsideTracker💡Noteworthy: Expert in longevity, nutrition, and personalized health optimization💡 Where to find them: LinkedInHost-at-a-Glance💡 Name: Ashley Reaver 💡What she does: Lead Nutrition Scientist💡Company: InsideTracker💡Noteworthy: Specializes in metabolism, nutrition, and biomarker-based health strategies💡 Where to find them: LinkedIn Episode highlights:[00:00:00] Introduction [00:02:02] Understanding GLP-1 Hormones[00:04:26] GLP-1 Receptor Agonists: Mechanism and Benefits[00:06:50] Impact of GLP-1 on Weight and Health[00:21:16] Side Effects and Considerations of GLP-1 Agonists[00:26:31] The Future of GLP-1 Agonists[00:34:54] Exploring Wearables for Health[00:36:08] Choosing the Right Wearable[00:40:29] Wearables for Detecting Illness and Falls[00:47:12] Conclusion and Final ThoughtsKey InsightsGLP-1 Agonists: A Breakthrough for Weight and Metabolic HealthGLP-1 agonists, originally developed for type 2 diabetes, have become a game-changer for weight loss, appetite control, and longevity. These drugs mimic natural gut hormones that regulate hunger and insulin secretion, helping people feel full longer and stabilizing blood sugar levels. Studies show that GLP-1 agonists can reduce body weight by up to 25%, a level comparable to bariatric surgery. Beyond weight management, these drugs may lower inflammation, improve cardiovascular health, and even reduce the risk of certain cancers. However, long-term use is likely necessary, as stopping the medication often leads to weight regain. Gil and Ashley emphasize the importance of medical supervision and highlight ongoing research into how GLP-1 impacts cognitive function and fertility.Long-Term Use of GLP-1 Agonists: Training the Body for Better HabitsMany wonder if GLP-1 medications are a short-term fix or a lifelong commitment. While the drugs suppress appetite, weight regain is common after stopping treatment. Gil suggests using this period as a training phase—learning to prioritize whole foods, avoid processed meals, and build sustainable habits. He also highlights the importance of exercise, especially strength training, as GLP-1 users risk losing muscle mass along with fat. Regular blood tests and nutrient monitoring are essential, as some users may experience vitamin deficiencies. The hosts caution against taking GLP-1 agonists solely for cosmetic weight loss and emphasize that obesity is a chronic, progressive condition requiring long-term management. This insight reinforces the idea that successful weight loss isn’t just about medication—it’s about lifestyle changes and long-term commitment.Wearables: The Future of Personalized Health TrackingWearables are reshaping how individuals monitor their health from fitness to disease prevention. Gil and Ashley break down Apple Watch, Oura Ring, and Whoop, each catering to different needs. Apple Watch excels at fall detection and emergency response, making it ideal for older adults. Oura Ring provides early illness detection through temperature and heart rate variability tracking. Whoop is favored by athletes for its detailed recovery insights and sleep monitoring. Wearables aren’t just for data collection—they drive behavior change, encouraging users to improve sleep, exercise, and stress management. With AI-driven health coaching on the rise, the hosts predict that wearables will play a central role in proactive healthcare and longevity strategies.Longevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit https://hubs.li/Q021Z4gp0 for 20% off any InsideTracker plan.
Precision Longevity Medicine with Dr. David Barzilai InsideTracker 2025-03-22 | Can personalized medicine unlock the secrets to living longer and healthier lives? In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. David Barzilai, a renowned longevity physician and founder of Barzilai Longevity Consulting, to explore the science of extending healthspan through precision and innovation.Dr. Barzilai shares his journey into biogerontology and longevity science, unpacking key concepts like the hallmarks of aging, the potential of lifestyle interventions, and the translation of findings from animal models to human health. He highlights how evidence-based lifestyle medicine—centered on nutrition, exercise, sleep, and stress management—can be tailored to individual needs using biomarker-driven strategies for maximum impact.The conversation delves into some of the most promising longevity interventions, from gerotherapeutics to cutting-edge supplements. Dr. Barzilai emphasizes the power of personalized approaches in optimizing healthspan and lifespan, offering listeners practical, science-backed insights to take charge of their longevity journey.Engaging and informative, this episode is essential listening for anyone curious about the future of longevity medicine and the innovations shaping how we age. Guest-at-a-Glance💡 Name: Dr. David Barzilai, MD, PhD💡What he does: Founder and CEO💡Company: Healthspan Coaching LLC💡Noteworthy: Renowned longevity physician integrating science and personalized health strategies.💡 Where to find them: LinkedIn (linkedin.com/in/agingdoc), X (https://x.com/agingdoc1?lang=en)Episode highlights:Introduction: 00:00:00Dr. Barzilai’s Journey into Science: 00:03:43The Importance of Translating Science into Practice: 00:10:00The Role of Social Media in Longevity Science: 00:16:37Defining Biogerontology: 00:22:32Understanding the Hallmarks of Aging: 00:24:27The Role of Lifestyle Medicine in Preventing Premature Mortality: 00:36:13Caloric Restriction and Its Effects on Lifespan: 00:37:33Human Trials and the Challenges of Compliance: 00:41:13The Potential of Rapamycin and mTOR Inhibitors: 00:42:05The Importance of Lifestyle Medicine: 00:51:25Precision Medicine: Tailoring Health Interventions: 01:02:56GLP-1 and Alcohol Absorption: 01:12:30Exercise and Mortality Reduction: 01:15:33Biomarkers and Metabolic Health: 01:19:38Longevity Drugs and Supplements: 01:25:43Epigenetic Reprogramming and Aging: 01:45:06We Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
Muscle, Longevity, and the Power of Protein with Dr. Gabrielle Lyon InsideTracker 2025-03-19 | In this episode of Longevity by Design, host Dr. Gil Blander welcomes Dr. Gabrielle Lyon, a board-certified family physician and New York Times bestselling author of Forever Strong. Gabrielle discusses the growing epidemic of sarcopenia, the loss of muscle mass and strength, accelerated by the use of GLP-1 medications. She emphasizes the importance of muscle health for overall longevity and introduces the concept of "muscle span."Gil and Gabrielle explore the critical role of skeletal muscle as a metabolically active organ, its impact on longevity, and the best ways to build and maintain muscle throughout life. They delve into the public's misconception of prioritizing today's needs over tomorrow's health, highlighting the need for preventative measures like strength training. The conversation touches upon the complexities of protein consumption, emphasizing the importance of meeting daily protein goals and the often-overlooked nutritional needs for healthy aging.Finally, they address common misconceptions regarding hormone replacement therapy and the importance of prioritizing muscle-centric medicine. This episode offers actionable insights and valuable knowledge for anyone seeking to optimize their health and longevity through a deeper understanding of muscle health.Guest-at-a-Glance💡 Name: Dr. Gabrielle Lyon 💡What they do: N/A💡Company: Dr. Gabrielle Lyon💡Noteworthy: Physician and New York Times bestselling author specializing in muscle-centric medicine and longevity.💡 Where to find them: LinkedIn, InstagramEpisode highlights:[00:01:09] Meet Dr. Gabrielle Lyon[00:06:09] The Importance of Muscle Health[00:09:37] Writing and Impact of 'Forever Strong'[00:14:45] The Role of Skeletal Muscle[00:21:54] Building and Maintaining Muscle[00:26:40] The New Epidemic: Muscle Loss[00:30:22] Optimizing Health with InsideTracker[00:39:41] The Importance of Healthy Skeletal Muscle[00:43:03] The Reality of Aging and Taking Action[00:45:43] Hormone Replacement Therapy: A Controversial Topic[00:53:52] Understanding Dietary Protein[01:00:23] Protein Consumption and Distribution[01:03:33] The Role of Animal-Based Products in Human Health[01:15:55] Supplements for Muscle Building and Health[01:17:51] Top Tips for Health Span and LongevityWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
The Science, Evolution, and Future of Lifespan and Healthspan with Dr. Michael Ringel InsideTracker 2025-03-05 | On this episode of Longevity by Design, Dr. Gil Blander speaks with Dr. Michael Ringel, COO of Life Biosciences, about the science of aging and longevity. Michael discusses how evolution influences lifespan and why aging occurs. He explains the trade-off between resource allocation for reproduction versus maintenance and repair within the body. Caloric restriction and its effects on lifespan are explored through an evolutionary lens.Michael highlights the challenges and breakthroughs in longevity research. He touches upon the role of genetics and pharmaceuticals in manipulating lifespan and healthspan. He points to the Pacific rockfish as an example of varying lifespans within a closely related group of species, demonstrating the genetic component of aging. He also notes the impact of Cell reprogramming, referencing a study on how specific Cell reprogramming can regenerate optic nerves.The conversation shifts to the business of longevity, where Michael discusses the increased interest and investments from big pharma and billionaires. He examines the economic benefits of extending healthspan, citing a potential value of $300 trillion from a 10-year healthspan extension in the US alone. Michael and Gil also explore the importance of lifestyle choices for healthy aging, emphasizing diet, exercise, sleep, stress management, and social connections.Guest-at-a-Glance💡 Name: Dr. Michael Ringel 💡What they do: COO💡Company: Life Biosciences💡Noteworthy: Biotechnology COO bridging science and business for longevity breakthroughs.💡 Where to find them: LinkedIn Episode highlights:[00:00:56] Meet Dr. Michael Ringel[00:02:30] Journey to Becoming a Scientist[00:04:26] Interest in Longevity and Aging[00:07:59] Evolution and Aging[00:21:04] Caloric Restriction and Lifespan[00:25:07] InsideTracker: Personalized Healthspan Optimization[00:26:02] Pharma's Role in Aging Research[00:37:32] Understanding Causality in Medical Research[00:38:09] Challenges of Observational Studies[00:39:40] Experimental Studies and the TAME Trial[00:40:21] Pharmaceutical Incentives and Metformin[00:40:56] Exploring Rapalogs and Patent Issues[00:43:39] Hallmarks of Aging and Future Prospects[00:45:59] Investment in Aging Research[00:52:35] Economic and Social Impacts of Longevity[01:02:30] Practical Tips for Extending LifespanWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
The doctor said Youre just old. He didnt buy it! Fight aging with Alan InsideTracker 2025-02-21 | Long time InsideTracker member, Alan discusses how he used InsideTracker to lower his InnerAge by a decade, lose weight, get in shape, and how he kept an eye on his overall wellness while he fought cancer and battled radiation. Congratulations Alan, and cheers to many more healthy years!
How Long Can Humans Live? Insights from Dr. Jay Olshansky InsideTracker 2025-02-19 | In this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Jay Olshansky, a leading professor at the University of Illinois Chicago and a renowned expert in aging and biodemography. Together, they delve into the science of longevity, exploring how public health advancements in the 20th century revolutionized life expectancy and what lies ahead in the quest to extend both lifespan and healthspan.Dr. Olshansky unpacks the biological limits of human longevity, shedding light on why life expectancy gains are slowing despite medical advancements. He explains the interplay between genetics, lifestyle choices, and aging, emphasizing how societal factors like inequality and access to healthcare impact longevity outcomes. Key concepts like "life table entropy" reveal why breakthroughs in aging science are essential to push beyond the current boundaries.Tune in to gain actionable insights on diet, exercise, and monitoring health—all crucial for maximizing healthspan, regardless of your genetic blueprint.Guest-at-a-Glance💡Name: S. Jay Olshansky, Ph.D.💡What he does: Professor at the University of Illinois Chicago School of Public Health💡Company: University of Illinois Chicago💡Noteworthy: Expert in aging, biodemography, and the biological limits of longevity.💡Where to find them: LinkedIn: linkedin.com/in/s-jay-olshansky-ph-d-2b67643Episode highlights:Introduction: 00:00:00Dr. Olshansky book: 00:05:40What was the lifespan 100 years ago and what is it today?: 00:08:00Average vs longer lifespan: 00:19:00Death rate at extreme old ages: 00:22:00What can break the lifespan ceiling?: 00:26:27What are the chances of someone living up to 120 years old?: 00:28:00Disparities in Longevity: The Social Determinants of Health: 00:32:00GLP-1 as a longevity drug: 00:37:00Why women live longer than men: 00:41:00How does becoming a U.S. president impact lifespan and healthspan?: 00:46:00How long can our listeners aim to live?: 00:50:00What are the key milestones in longevity discoveries over the past few decades?: 00:55:00What is your top tip for a health span and longevity: 01:15:33We Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
Heather Caseys Cognition Story InsideTracker 2025-02-04 | Heather Casey dives deep into how cortisol was affecting her cognition and how she used InsideTracker's Category Testing to get specific about her needs towards optimized health. learn more www.insidetracker.com
Category Tests in action: Amandas inflammation story InsideTracker 2025-01-24 | Test what you want, when you want. Listen to how Amanda uses Category Testing to reach her goals. www.insidetracker.com
New! Category Tests InsideTracker 2025-01-24 | Test what you want, when you want. Hit your health goals faster by choosing from a menu of 10 hyper-focused blood tests. With each one you receive: Analysis for 6 to 14 biomarkers, depending on which test you chooseAn updated Healthspan Category Score based on your blood test and any relevant fitness-tracker dataPersonalized recommendations to help drive your category score higherProgress tracking to monitor your health over time and see where your score is headingLow-cost testing with options ranging from $99 to $149It's your health, you decide what to test. With InsideTracker. www.insidetracker.com
How Can a Nutrition AI Platform Help Us Live Healthier and Longer with Dr. Dmitriy Richard Starson InsideTracker 2025-01-22 | On this episode of Longevity by Design, Dr. Gil Blander hosts Dr. Dmitriy Richard Starson, Founder and CEO of Passio, an AI-powered nutrition coaching platform. Dmitriy discusses his career path from astrophysics to the world of nutrition tracking. He explains how his company seeks to make healthy eating more accessible. Passio aims to achieve this through user-friendly technology like food scanning, voice logging, and personalized AI coaching.Dmitriy believes this technology will revolutionize how people approach nutrition. He envisions a future where food tracking is as commonplace as step tracking. This shift, combined with insights from companies like InsideTracker, could lead to personalized nutrition and supplementation plans. Such advances have the potential to slow or even reverse aging and age-related diseases.While acknowledging the influence of the food industry, Dmitriy remains optimistic. He sees a future where individuals have the knowledge and tools to make informed decisions about their health. Through personalized nutrition and data-driven insights, people can optimize their health and work toward increased longevity.Episode highlights:Introduction: 00:00:00From Astrophysics to Nutrition: An Unlikely Journey?: 00:06:00The Power of AI in Food Logging: 00:11:00The "Human" Factor: Addressing Challenges with Data Accuracy: 00:22:00AI and the Healthcare System: A Balancing Act?: 00:45:00Top tip to improve healthspan: 00:50:00We Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
The Path to a 1,000-Year Lifespan with Dr. Aubrey de Grey InsideTracker 2025-01-08 | In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Aubrey de Grey, a biomedical gerontologist, to explore the frontiers of aging research and lifespan extension. Dr. de Grey shares his work identifying and addressing the seven major categories of aging-related diseases. He discusses how targeted damage repair offers a promising alternative to traditional methods to slow aging, providing a path to longer, healthier lives.The conversation delves into the hallmarks of aging, their implications for medical research, and the challenges of translating results from animal models to human applications. Dr. de Grey emphasizes the importance of combining multiple interventions, such as senolytics, gene therapy, and stem cell treatments, to achieve significant gains in lifespan. He also shares insights from his work with the LEV Foundation and the Methuselah Foundation.Listeners will gain a deeper understanding of the science behind rejuvenation and the potential for humanity to reach longevity escape velocity within the coming decades. Dr. de Grey underscores the critical role of continued research, innovation, and funding in accelerating progress toward defeating aging-related diseases.Episode highlights:Introduction: 00:00:00The Seven Hallmarks of Aging: A Foundational Framework: 00:07:00Challenges in Funding Longevity Research: 00:15:00Lifestyle, Genetics, and the Limits of Current Longevity: 00:23:00The Methuselah Foundation and Early Longevity Advocacy: 00:37:00Top tip to improve healthspan: 00:52:00We Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
Dietary Changes to Reduce the Risk of Prostate Cancer with Dr. John Erdman InsideTracker 2024-12-18 | On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. John Erdman to discuss prostate cancer and the impact of diet on disease progression. John shares his personal connection to this disease and why he’s dedicated his research to understanding dietary interventions.John explains that prostate cancer is often slow-growing, with most men experiencing decades between early mutations and noticeable tumor growth. He stresses the importance of early detection through regular checkups, including digital exams and PSA tests. While the medical community debates the effectiveness of these tests, John advocates for establishing a baseline to monitor for any sudden changes.John's research reveals a strong link between tomato consumption and reduced prostate cancer risk. He believes this protective effect stems from lycopene and its metabolites, which may influence gene expression. John emphasizes that while tomato consumption shows promise, maintaining a healthy weight and regular exercise are equally crucial for long-term health.Episode highlights:Introduction: 00:00:00The Stages and Progression of Prostate Cancer: 00:06:00Diagnosing Prostate Cancer: Methods and Considerations: 00:11:00The Role of Specific Foods in Prostate Cancer Risk Reduction: 00:22:00Exploring the Link Between Gut Microbes and Prostate Cancer: 00:30:00Top tip to improve healthspan: 00:34:00We Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcast
Dr. Jens Juul Holst on GLP-1’s Life-Changing Impact on Metabolic Health InsideTracker 2024-12-04 | In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Jens Juul Holst, a renowned Danish physician and physiologist, to discuss GLP-1, a hormone transforming our understanding of metabolic health. Dr. Holst, who discovered and described GLP-1, explains its role as a gut-derived hormone that regulates appetite, insulin secretion, and digestion, offering a groundbreaking approach to managing obesity and type 2 diabetes.The conversation explores how GLP-1 receptor agonists, have evolved into powerful medications. These drugs help patients achieve significant weight loss, reverse diabetes, improve cardiovascular health, reduce inflammation, and potentially enhance cognitive function. Dr. Holst delves into their long-term implications for preventing diabetes, extending health spans, and even reducing the risks of obesity-related cancers and improving fertility.Dr. Holst emphasizes that while GLP-1 offers life-changing benefits, sustainable health still hinges on balanced diets and regular physical activity. This episode provides a fascinating look at the intersection of science, medicine, and lifestyle in promoting longevity.Sign up for updates about each new episode: info.insidetracker.com/longevitybydesignView show notes here: blog.insidetracker.com/longevity-by-design-podcast-jens-juul-holstEpisode highlights:Introduction: 00:00:00What is GLP-1: 00:03:00what is a GLP-1 agonist: 00:04:15what are the target organs of the GLP-1 agonist?: 00:06:30what is the effect of the GLP-1 agonist on a diabetic patient?: 00:10:00What percentage of a diabetic patient on GLP-1 have complete remission: 00:11:30How long did it take to bring a drug to market from the moment you first discovered it: 00:23:30What is the GLP-1 effect on cognition and dementia: 00:29:00GLP-1 effect on kidney diseases: 00:32:00GLP-1 positive effect on fertility: 00:35:00GLP-1 positive effect on cancer: 00:37:30Should a patient be on GLP-1 for life: 00:41:00GLP-1 related side effects: 00:48:00GLP-1 effect on resting heart rate: 00:52:30GLP-1 related side effects: 00:48:00GLP-1 from Lilly vs novo nordisk: 00:55:00GLP-1 oral versus the injectable: 00:58:00GLP-1 effect on lifespan: 01:00:30GLP-1 effect on lifespan: 01:00:30What led you to become a scientist: 01:03:00The story of discovering the GLP-1: 01:04:30How did you successfully extend the half-life of the GLP-1 agonist: 01:09:00GLP-1 moving from once a day to once a week: 01:16:00Top tip to improve healthspan: 01:18:00GLP-1 Agonists: A Game-Changer for Diabetes and ObesityDr. Jens Juul Holst explores the revolutionary impact of GLP-1 agonists in treating diabetes and obesity. These medications mimic a natural gut hormone to regulate insulin secretion, appetite, and weight. Through their ability to normalize blood glucose levels and promote significant weight loss, GLP-1 agonists have transformed the lives of patients with type 2 diabetes and obesity. Holst highlights their success in enabling over 50% of diabetes patients to achieve normal glucose levels while addressing the systemic health risks tied to obesity. This innovation represents a monumental leap in metabolic disease management.Beyond Weight Loss: Cardiovascular and Inflammatory Benefits of GLP-1Dr. Holst emphasizes the additional health advantages of GLP-1 agonists, beyond their effects on diabetes and obesity. These drugs improve cardiovascular outcomes by reducing major adverse events such as heart attacks and strokes. They also decrease systemic inflammation, a common issue in metabolic diseases. Holst points out that GLP-1 therapy’s dual action on vascular health and inflammation positions it as a comprehensive solution for improving long-term health outcomes in patients with diabetes or obesity. The Impact of GLP-1 on FertilityDr. Holst explores GLP-1’s surprising potential in fertility treatments, particularly for individuals with metabolic-related infertility issues, such as polycystic ovary syndrome (PCOS). He explains that improving metabolism and reducing insulin resistance with GLP-1 therapy can enhance fertility outcomes for both men and women. Although he urges caution due to limited long-term data, Holst notes the promising effects observed in clinical experiences.“If you can ameliorate the metabolism of these individuals, they will immediately become pregnant. And we knew that already. You can even do it with metformin…Once GLP-1s were introduced, it turned out that yes, these people became pregnant.”We Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcastFor science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
Food Fermentation and Its Effect on Healthspan with Dr. Jacob Allen and Dr. Mike Miller InsideTracker 2024-11-20 | In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Jacob Allen and Dr. Mike Miller to discuss their research on the impact of fermented foods on health and longevity.Jacob and Mike begin by breaking down the science of fermentation, explaining that it involves using microorganisms like yeast and lactic acid bacteria to transform food products. This process not only leads to distinct flavors but also extends the shelf life of food, which was critical in times before refrigeration. They emphasize that while many fermented foods contain live cultures, not all meet the specific criteria for being considered "probiotics," which require scientific evidence of health benefits.Jacob and Mike are particularly interested in lactic acid fermentation, found in foods like yogurt, kimchi, and sauerkraut, and its potential to reduce systemic inflammation. They discuss their research, which examines how certain metabolites, especially aryl lactates, produced during fermentation interact with immune cells. Though research is still ongoing, they believe these metabolites may contribute to the health benefits associated with fermented food consumption.Episode highlights:Introduction: 00:00:00Why have you decided to become a scientist: 00:02:30What is fermentation: 00:07:45What microbes are involved in fermentation: 00:08:40How those microbes get into the fermented food: 00:09:35When the Humankind started to utilize fermentation: 00:11:20What is the difference between Probiotics and Live Cultures: 00:15:15What are the benefits of fermented food consumption: 00:17:43What foods are produced through lactic acid fermentation, and what are the best methods for making them at home: 00:23:10What is the positive effect of fermented foods on inflammation: 00:29:18What impact do fermented foods have on longevity: 00:32:10What are Postbiotics: 00:35:05Top tip for healthspan: 00:44:20Not all Fermented Foods Are EqualWhile many cultures around the world have enjoyed the benefits of fermented foods for centuries, modern consumers need to be savvier about what they’re buying. Just because a food is fermented or contains live cultures doesn’t mean it offers proven health benefits. The term "probiotics" is specifically defined and requires scientific evidence to support health claims, so don’t be afraid to read labels carefully and choose fermented foods backed by research. Lactic Acid Fermentation May Be a Key Player in HealthWhile there are many types of fermentation, lactic acid fermentation, which is responsible for foods like yogurt, kimchi, and sauerkraut, is of particular interest to researchers. Early studies show promising links between consuming lactic acid-fermented foods and positive impacts on gut health, immune function, and even potentially longevity. The specific mechanisms are still being investigated, but it seems these foods offer more than just interesting flavors. Scientists Are Unlocking the Power of PostbioticsScientists are going beyond probiotics and exploring the potential of “postbiotics” – those beneficial compounds produced by bacteria during fermentation. These metabolites may hold the key to unlocking even more targeted health benefits from fermented foods. Dr. Allen and Dr. Miller’s research on aryl lactates, for instance, suggests that some postbiotics could help modulate immune responses and address inflammation. This area of study is rapidly evolving and offers an exciting frontier in food science and human health.The History and Significance of FermentationLong before refrigeration, humans discovered the magic of fermentation. This process, dating back thousands of years, involves harnessing the power of microbes to transform food. What began as a way to preserve food has evolved into an art form, with diverse cultures developing unique fermentation traditions that add flavor and depth to their cuisines."A lot of these fermentation practices keep foods for a much longer period of time without refrigeration and we did not have refrigeration until 100 years ago." - Dr. Jacob AllenWe Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcast
Taste and Smell Preferences and Their Impact on Health with Dr. Yanina Pepino InsideTracker 2024-11-06 | On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Yanina Pepino, Professor of Ingestive Behavior at the University of Illinois, to discuss the fascinating link between taste, personal preferences, and long-term health. Yanina's research shows our food environment significantly shapes cravings. This exposure starts as early as the womb, impacting future preferences.Yanina explains that bariatric surgery and GLP-1 medications are powerful tools for weight management. However, she emphasizes the importance of using these interventions as opportunities to adopt healthier eating habits. She highlights the potential of GLP-1 agonists as a treatment for alcohol use disorder, noting their ability to reduce alcohol cravings.The conversation also explores the impact of non-nutritive sweeteners. While generally considered safe, Yanina's research suggests that these sweeteners may have metabolic effects. She encourages listeners to be mindful of their intake and to prioritize natural sugars in moderation.Episode highlights:Introduction: 00:00:00Why have you decided to be a scientist: 00:03:40How did you get interested in the taste & smell preference in humans: 00:04:40The Impact of Maternal Alcohol Consumption During Pregnancy on Newborn Alcohol Preferences: 00:06:00What you consume during pregnancy can influence your newborn’s preferences: 00:08:00What Are the Individual Differences in Human Taste: 00:08:20Do you know if taste perception is influenced by an individual’s specific macro- and micronutrient needs: 00:14:00What are the effects of bariatric surgery-induced weight loss on flavor perception, eating behavior, and alcohol drinking: 00:16:00The Impact of GLP-1 Drug Use on flavor perception: 00:26:45The Impact of lifestyle related weight losss on flavor perception: 00:30:10The Negative Impact of Alcohol Consumption on Bariatric Surgery Patients: 00:34:30The potential positive Impact of GLP-1 injection on Alcohol Consumption: 00:39:30What Is the Effect of Non-Caloric Sweeteners on Post-Meal Glucose Spikes and health: 00:41:30Bitter taste and why some of us don't like it: 00:52:00Lessons from the COVID-19 Pandemic on Taste and Smell Perception: 00:54:30Yanina's top tip for healthspan: 00:42:10Early Taste Exposure Shapes Lifelong PreferencesWhat we eat during pregnancy and infancy might pre-program a child's future food preferences. Yanina's research reveals that exposure to flavors, even in the womb, can influence what we enjoy eating later in life. This highlights the importance of establishing healthy eating patterns from the very beginning, as those early experiences can have lasting effects. Parents and caregivers have a powerful role in shaping those early preferences for a healthier future generation.Bariatric Surgery and GLP-1 Offer a Chance to "Reset"Both bariatric surgery and GLP-1 medications are not just quick fixes, but opportunities to rewire your relationship with food. While these interventions can significantly impact hunger hormones and promote weight loss, their long-term success relies on behavioral change. Yanina stresses the importance of using this period of altered appetite to explore new, healthier food choices and establish lasting dietary habits.Don't Be Fooled by "Zero-Calorie" SweetenersWhile considered safe, non-nutritive sweeteners might have unintended consequences for our metabolism. Yanina's work suggests that these sweeteners, despite lacking calories, can still impact insulin response and potentially contribute to insulin resistance. This emphasizes that these artificial sweeteners are not a free pass for a sweet tooth. Moderation and prioritizing natural sugars in limited amounts remain crucial for metabolic health.Why Diets Fail: It's Not Just WillpowerLosing weight through lifestyle changes alone can feel like an uphill battle. Yanina explains that it's not simply a lack of willpower but a complex interplay of biological factors. Once we gain weight, particularly fat, our metabolism changes, making it harder to control hunger. Bariatric surgery and GLP-1 agonists offer an advantage by directly addressing those hunger signals, providing a window to establish healthier habits."It is very difficult. It doesn't mean it cannot be doable. A lot of people can do it, they lose weight, and they're able to keep it off, but the problem is that once a person gains body weight — in particular, once you gain fat — there are a lot of things in the metabolism that make it very difficult to tame your hunger."We Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcast
Ask Me Anything (AMA): Nutrition Deep Dive with Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD InsideTracker 2024-10-23 | In this special "Ask Me Anything" episode of the Longevity by Design podcast, Ashley Reaver and Dr. Gil Blander from InsideTracker delve into their latest innovation, the Nutrition Nutrition Deep Dive Solution. After years of research and development, they share the journey of creating a food recognition platform that helps users track their food intake in real-time. The goal is to provide users with personalized recommendations for better health and nutrition based on their dietary habits.Dr. Blander explains the challenges that arose over nearly a decade of development, including the complexity of assessing nutritional needs accurately. Through collaboration with experts from Tufts School of Nutrition, InsideTracker has refined its approach, incorporating not only food frequency questionnaires but also real-time food logging. This solution enables users to optimize their intake of macro and micronutrients to improve health outcomes.Ashley emphasizes how this technology allows for a more holistic view of a person's nutrition and its impact on biomarkers, performance, and sleep. With the addition of real-time data, users can now receive tailored insights that align with their fitness and wellness goals.Episode highlightsIntroduction: 00:00:00Nutrition Deep Dive Ideation: 00:01:35Why the Development of the Nutrition Solution Took So Long: 00:02:50What is the problem we tried to solve: 00:05:25What is the Value of the Nutrition Deep Dive for the User: 00:07:00What Are the Expectations for a Nutrition Deep Dive User: 00:09:25What Does a Nutrition Deep Dive User Receive in Exchange for One Week of Nutrition Logging: 00:11:50How Often Should Nutrition Deep Dive Users Complete the 7-Day Logging: 00:16:35Why 7-Days Logging: 00:19:00Summary 00:21:10The Evolution of the Nutrition Deep DiveInsideTracker's Nutrition Deep Dive was a decade-long project aimed at solving the challenge of personalized nutrition. Dr. Blander explains that the project began with the realization that no one had figured out how to match the right food with the right person at the right time. The team worked extensively, developing multiple iterations, collaborating with leading scientists, and employing cutting-edge technology, including food recognition platforms and barcode readers. Despite the prolonged process, their persistence led to a comprehensive solution that analyzes user input, such as food consumption and biomarker data, to offer personalized nutritional insights.Food Tracking Technology: A Game-ChangerOne of the most exciting aspects of InsideTracker’s Nutrition Deep Dive innovation is its food recognition technology. Users can log food through various methods, including scanning barcodes or using their iPhone camera to identify food items. The system is capable of analyzing over 4,000 foods, and the database is continuously expanding. This ability to gather real-time nutrition data revolutionizes how users can assess their diet. When paired with data from fitness trackers, the insights help to better understand the connection between food, sleep, exercise, and overall performance, thus optimizing health.The Importance of Timing in NutritionInsideTracker's Nutrition Deep Dive feature introduces a new way of thinking about the timing of food intake. The system not only tracks what users eat but also when they eat, sleep, and exercise. This timing is crucial as it affects everything from performance to sleep quality. For example, eating too late or failing to consume nutrients after exercise can negatively impact recovery and overall health. InsideTracker’s machine learning algorithms analyze this data and offer personalized recommendations to ensure users are optimizing their food intake for maximum benefit.Challenges of Accurately Assessing Nutrition InsideTracker recognizes the difficulty in getting a precise measurement of what people truly eat. Ashley Reaver explains how existing methods like food frequency questionnaires only provide rough estimates and are often inaccurate due to memory recall issues. The new approach aims to overcome these limitations by incorporating real-time food tracking technology, which allows users to report their intake as they go. This method offers more reliable and actionable insights.We Appreciate You!As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: info.insidetracker.com/podcast
What did Biolayne find in his InsideTracker bloodwork? | Dr. Layne Norton InsideTracker 2024-10-21 | Layne Norton, PhD, is a fitness and nutrition coach and a powerlifting world champion. Here he walks through his third set of InsideTracker blood results. He breaks down some surprising results and explains how to think about biomarkers that fall outside the optimal range.
The Impact of AI, ML, and Large Language Models on Your Health and Wellness With Dr. Renee Deehan InsideTracker 2024-09-25 | In this episode of Longevity by Design, Dr. Gil Blander talks with Dr. Renee Deehan, Senior Vice President of Science and AI at InsideTracker. They explore the world of artificial intelligence and its applications in health and wellness.Renee explains the differences between AI, machine learning, and large language models (LLMs). She discusses how InsideTracker has developed a specialized LLM called Ask InsideTracker. This tool allows users to interact with a vast knowledge base of health and wellness information.The conversation delves into the potential future applications of AI in personalized health recommendations. Renee emphasizes the importance of data privacy and security when developing these tools. She also shares her perspective on the broader impact of AI in various industries and its potential to enhance decision-making processes.Episode highlights:Introduction: 00:00:00Defining AI and Machine Learning in Simple Terms: 00:04:00AI is a branch of computer science: 00:05:00The Power and Limitations of Large Language Models: 00:08:00Developing Specialized AI Tools for Health and Wellness: 00:25:00GPT general foundational model: 00:26:00The Future of AI in Personalized Health Recommendations: 00:37:00A balance between nutrition, exercise, and recovery: 00:47:00The best habit that you can do: 00:48:00Specialized LLMs Enhance Health Information AccuracyLLMs tailored to specific domains can significantly improve the quality and reliability of information provided to users. By constraining general AI models with specialized knowledge, such as InsideTracker's corpus of health and wellness blog posts, these tools can deliver more accurate and relevant answers. This approach helps filter out noise and misinformation often found in general internet searches. For health and wellness applications, specialized LLMs can offer personalized insights based on high-quality, expert-reviewed content. This method bridges the gap between vast amounts of available information and individual user needs, potentially revolutionizing how people access and understand health-related information. AI in Health: Balancing Personalization and PrivacyThe integration of AI in health and wellness platforms promises highly personalized recommendations but raises important privacy concerns. As these systems evolve to incorporate individual health data, such as biomarkers and lifestyle information, the potential for tailored advice increases dramatically. However, this advancement requires robust security measures to protect sensitive personal information. The challenge lies in creating AI systems that can access and analyze personal health data while maintaining strict privacy standards. Striking this balance is crucial for the widespread adoption and trust in AI-powered health tools, potentially transforming how individuals manage their health and make lifestyle decisions. Continuous Refinement Key to AI Tool EffectivenessThe development and improvement of AI tools, particularly in health and wellness, require ongoing refinement based on user interactions and feedback. This iterative process involves analyzing user queries, identifying areas of improvement, and continuously updating the AI model. By studying how users interact with the tool and the types of questions they ask, developers can enhance the AI's ability to provide relevant and accurate information. This approach ensures that AI tools evolve to meet user needs more effectively over time. The continuous refinement process is crucial for maintaining the tool's reliability and relevance, especially in rapidly evolving fields like health and wellness.Longevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit https://hubs.li/Q02BxrGL0 for 10% off any InsideTracker plan.______________________________________Let’s Connect!Instagram - / insidetracker Twitter - / insidetracker Facebook - / insidetracker LinkedIn- / insi. .TikTok- / insidetracker_ Pinterest- / insidetrack. .Website - insidetracker.com
Introducing Nutrition DeepDive InsideTracker 2024-09-24 | Ready for personalized nutrition advice? Nutrition DeepDive is here!Here's how it works:1. For one week, you'll enter your foods, beverages, and supplements into the InsideTracker app.2. Nutrition DeepDive will analyze your intake in the context of your DNA, fitness tracker data, and most recent blood results.3. You'll get a detailed report full of nutritional insights—including advice on exactly what and when to eat for optimal health.This is a first-of-its-kind tool that connects your nutrition to your overall health goals. And it's available now for InsideTracker members with an iOS app!Product highlights:-7 days of food logging-Analysis for 15 key nutrients-A spotlight on the 5 nutrients having the biggest impact on your health-Meal timing insights that affect your fitness and sleep-Breakdown of how well protein is distributed throughout your day-Personalized food and supplement advice for improving your blood biomarkers-Easy-to-read graphs that help you see the impact of each food decision
The Surprising Link Between Space Travel and Aging with Dr. David Furman InsideTracker 2024-09-11 | Dr. David Furman is an associate professor at the Buck Institute for Research on Aging. He's done groundbreaking research on inflammaging, which is chronic, low-grade inflammation that can accelerate the aging process.With the help of hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, he'll explore that on this episode of Longevity by Design.You'll discover how David's team developed a new inflammatory age test, which is soon to be available from his company Edifice Health. The test uses five key proteins to assess an individual's inflammatory state and predict future health risks.You'll also learn about the surprising link between space travel and accelerated aging, which stems from the impact of microgravity on the body.There are insights here you can take into your daily health routine. To that end, you'll hear some practical tips on combating inflammation and promoting longevity. You can do this through lifestyle choices and a deeper understanding of your own personal health data.Episode highlights:Introduction: 00:00:00Why have you decided to be a scientist and not a painter: 00:04:001000 Immunomes: 00:06:00What is the immune system: 00:16:00Biomarkers related to the immune system: 00:18:00The development of frailty during the aging process: 00:21:00what inflammation is: 00:27:00Lifestlye dependent chronic stress: 00:31:00Inflammation-related biological clock: 00:34:00Epigenetic age: 00:38:00Centenarians and inflammatory markers: 00:48:00Space flight and inflammation: 00:51:00Astronauts aging: 00:55:00Microgravity as a stressor: 00:59:00Future of David's work: 01:04:00Summary: 01:06:00Not All Biological Age Clocks Are Created EqualWhile various biological age clocks exist, including epigenetic and glycan clocks, David's research highlights the benefits of protein-based clocks like his inflammatory age test. Unlike other clocks that closely correlate with chronological age, inflammatory age reveals more about an individual's biological state and potential health risks, offering valuable insights beyond simply reflecting the passage of time. Additionally, understanding how specific proteins link to inflammation allows for actionable lifestyle and dietary changes to positively impact those markers and potentially slow down the aging process. Lifestyle Choices Directly Impact Our Inflammatory LevelsMany modern lifestyle factors, often a far cry from our evolutionary past, contribute to chronic inflammation. These include exposure to environmental toxins like plastics and pesticides, poor sleep quality, disruptions to our circadian rhythm, social isolation, and chronic stress. By minimizing these exposome factors and adopting healthier habits—such as consuming whole foods, prioritizing sleep hygiene, and managing stress—we can potentially lower inflammation and support healthier aging. Space Travel Offers a Unique Perspective on Accelerated AgingAstronauts, despite being otherwise healthy individuals, experience accelerated aging due to the stressors of space travel, particularly the effects of microgravity. This provides valuable data on aging mechanisms that can be applied to Earth-bound research. By studying the physiological changes astronauts undergo, scientists can gain a deeper understanding of aging processes and potentially develop interventions to mitigate age-related decline for everyone.
Improvements in Biomarkers in a Digital Health Platform with Dr. Renee Deehan and Nimisha Schneider InsideTracker 2024-08-28 | In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Renee Deehan and Nimisha Schneider from InsideTracker to discuss the role of personalized health and the advancements made through data science and artificial intelligence. Dr. Deehan elaborates on her background in molecular biology and how she transitioned to computational biology, emphasizing the importance of integrating large-scale biological data to develop high-resolution molecular models of diseases.Nimisha Schneider shares her journey from basic immunology research to computational biology, highlighting the significance of building mathematical models to understand biological scenarios better. She explains how InsideTracker uses AI and machine learning to analyze users' blood biomarkers, genetic data, and fitness tracker information to provide personalized health recommendations. The discussion includes the integration of over 7,000 clinical studies into InsideTracker's AI engine, Segterra X, to offer tailored advice based on individual health data.The conversation dives into the findings from a recently submitted study involving 20,000 users, showing significant improvements in key health markers like LDL cholesterol, A1c, and ApoB over several years. Dr. Deehan and Schneider stress the importance of lifestyle changes and sustained efforts to achieve long-term health benefits. They also discuss the challenges posed by genetic predispositions and how personalized recommendations can help mitigate these risks. The episode concludes with insights into future research directions and the continuous development of personalized health solutions at InsideTracker.Key InsightsPersonalized Health Interventions Show Sustained ImprovementsA study involving 20,000 users of InsideTracker demonstrated that personalized health interventions correlate with significant and sustained improvements in key health markers. Users who followed personalized recommendations for nutrition, exercise, and lifestyle changes saw notable reductions in LDL cholesterol, A1c, ApoB, and many other biomarkers related to healthspan. These improvements were observed over several years, indicating the long-term efficacy of personalized health plans. The data suggests that consistent adherence to tailored health recommendations can help manage and even reverse risk factors associated with chronic diseases. This underscores the potential of digital health platforms to drive lasting positive health outcomes.Genetic Risk Influences Health OutcomesThe study explored the relationship between genetic risk scores and health outcomes, particularly focusing on cholesterol levels and metabolic health. Users with higher genetic risk for high LDL cholesterol, total cholesterol, or Ferritin levels found it more challenging to improve these markers compared to those with lower genetic risk. Despite the genetic predisposition, significant improvements were still achievable with persistent lifestyle changes. This highlights the importance of understanding one's genetic risk as a factor in personal health management and the potential benefits of personalized interventions in overcoming genetic disadvantages. It also emphasizes that genetics is not a definitive determinant, and lifestyle changes can substantially mitigate genetic risks.Activity Levels Correlate with Health ImprovementsAnalysis of fitness tracker data revealed that increased physical activity, measured via step count, was a key differentiator between users who successfully improved their health markers and those who did not. On average, users who increased their daily step count to around 11,000 steps showed significant improvements in cholesterol levels. In contrast, those who maintained lower activity levels saw less progress. Additionally, higher quality sleep, particularly increased REM sleep, was associated with better health outcomes. These findings illustrate the critical role of regular physical activity and good sleep hygiene in achieving and sustaining health improvements, providing actionable insights for users looking to optimize their health through lifestyle modifications.Episode highlights:Introduction: 00:00:00What is AI: 00:04:00What is ML: 00:05:00What is a foundation model? What is a large language model (LLM): 00:00:08What are the limitation of LMM in text development: 00:14:00How LLM is used for health and wellness questions? What InsideTracker developed in this domain: 00:17:00What is Ask InsideTracker: 00:25:00What is the difference between Ask InsideTracker and Chat GPT: 00:30:00What is next for LLM in InsideTracker: 00:36:00What is the future of LLM generally: 00:42:00What would you recommend to a person who like to live better and longer: 00:47:00
Parkinsons and Alzheimers: The Gut-Brain Connection Explored with Dr. Julie Andersen InsideTracker 2024-08-15 | In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses her groundbreaking work on neurodegenerative diseases, focusing on Parkinson's and Alzheimer's. She explains how the field of geroscience is transforming our understanding of aging, revealing that common underlying processes in various diseases could lead to universal therapeutic approaches.Dr. Andersen dives into the gut-brain connection, highlighting how gut health significantly impacts brain aging and the progression of neurodegenerative diseases. She also emphasizes the importance of cellular senescence, a process where aging cells stop dividing, contributing to diseases like Alzheimer's. Her research explores innovative ways to slow or prevent these processes, paving the way for new treatments.The episode concludes with Dr. Andersen advocating for lifestyle interventions, particularly exercise, as powerful tools in preventing neurodegenerative diseases. She underscores the potential of personalized medicine in tailoring treatments to individual aging patterns, offering hope for more effective and targeted therapies.Episode highlights:Introduction: 00:00:00Dementia as a side effect of aging: 00:06:00Dementia prevalence in the population: 00:10:00The environment and Alzheimer's disease: 00:15:00Biological sex effect on Dementia 00:17:00Ethnicity effect on Dementia 00:18:00What to expect when you are diagnosed with Dementia 00:19:00Biomarkers for Dementia 00:26:00The connection between the hallmarks of aging and Dementia: 00:30:00 Exercise and Dementia: 00:34:00disruption of REM sleep as an early sign of Parkinson's: 00:37:00What is the current treatment for Parkinson's: 00:38:00Cellular senescence and neurodegenerative diseases: 00:42:00Beta amyloid plaques and Alzheimer's disease: 00:50:00Autophagy and dementia: 01:00:00What would you recommend to a person who like to live better and longer: 01:08:00Longevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit https://hubs.li/Q02BxrGL0 for 10% off any InsideTracker plan.______________________________________Let’s Connect!Instagram - / insidetracker Twitter - / insidetracker Facebook - / insidetracker LinkedIn- / insi. .TikTok- / insidetracker_ Pinterest- / insidetrack. .Website - insidetracker.com
Real Client Results InsideTracker 2024-08-15 | InsideTracker Pro client, Jamie Dworkin, shares his personal testimonial of how the use of InsideTracker combined with guidance from his trainer, Gary Blacklegde has been transformational in his fitness journey.
“The Solution I’ve Been Looking For” InsideTracker 2024-08-15 | InsideTracker Pro Gary Blackledge shares why InsideTracker was the solution he was looking for, for himself and his clients.
The Power of Coach/Client Relationships InsideTracker 2024-08-15 | InsideTracker Pro Gary Blackledge sits down with one of his longtime clients, Jamie Dworkin, to discuss how InsideTracker has leveled up their coach/client relationship.
The impact of ketones on performance and aging with Dr. Brianna Stubbs InsideTracker 2024-08-07 | In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Brianna Stubbs, an expert in exogenous ketone metabolism. Dr. Stubbs shares her journey from being a competitive rower to becoming a scientist. She dives into her research on ketone biology and its implications for health and aging.Dr. Stubbs discusses the science behind ketones, explaining how they serve as an alternative fuel for the brain and body, particularly during periods of low carbohydrate intake. She highlights the potential benefits of ketones for cognitive function and heart health, noting their ability to act as signaling metabolites that influence oxidative stress and inflammation.The conversation also explores the practical applications of ketone supplements for athletes and the general public. Dr. Stubbs emphasizes the importance of personalized approaches to diet and supplementation, considering individual goals and health conditions. She provides insights into her ongoing research at the Buck Institute, aiming to translate scientific discoveries into practical tools for healthy aging.Episode highlights:Introduction: 00:00:00Brain and ketones: 00:17:00Ketones effect on oxidative stress or inflammation: 00:19:00ketone drink and ketosis: 00:20Benefits of Ketogenic Diet Beyond Weight Loss: 00:39:00ketones and heart health: 00:44:00Exercise and Brain Health: 00:46:00Clinical Research on Ketone Supplements: 00:48:00Longevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit https://hubs.li/Q02BxrGL0 for 10% off any InsideTracker plan.______________________________________Let’s Connect!Instagram - / insidetracker Twitter - / insidetracker Facebook - / insidetracker LinkedIn- / insi. .TikTok- / insidetracker_ Pinterest- / insidetrack. .Website - insidetracker.com
The Impact of Ultra-Processed Foods and Fructose on Metabolic Health With Dr. Robert Lustig InsideTracker 2024-08-07 | In this episode of Longevity by Design, our host Dr. Gil Blander talks with Dr. Robert Lustig, an emeritus professor of pediatrics at UCSF, a renowned neuroendocrinologist, obesity expert, and anti-sugar advocate. Dr. Lustig dives into the impact of ultra-processed foods and fructose on metabolism, emphasizing how these contribute to obesity and metabolic diseases. He also discusses his journey from academia to public health advocacy, aiming to reform the food industry and reduce chronic diseases.Episode highlights:Introduction: 00:00The Role of Insulin in Obesity and Metabolism 00:08:00The Influence of Big Food Industries on Public Health Policies 00:29:16The Misconception of Dietary Fats 00:40:0The Impact of Stress on Visceral Fat 00:49:27Longevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit https://hubs.li/Q02BxrGL0 for 10% off any InsideTracker plan.______________________________________Let’s Connect!Instagram - / insidetracker Twitter - / insidetracker Facebook - / insidetracker LinkedIn- / insi. .TikTok- / insidetracker_ Pinterest- / insidetrack. .Website - insidetracker.com
Ask Me Anything (AMA): Optimizing Health and Longevity with Dr. Gil Blander and Ashley Reaver InsideTracker 2024-08-05 | In the latest Ask Me Anything, Ashley and Dr. Blander answer popular questions about optimizing health and longevity. Dr. Blander discusses the rationale behind InsideTracker's shift to a subscription model, emphasizing the importance of continuous engagement for long-term health improvement. He explains how this model encourages users to maintain their health optimization practices consistently over time, enhancing the overall effectiveness of their health plans.Ashley and Dr. Blander also dive into the recent updates to InsideTracker’s blood work page, which now categorizes biomarkers into healthspan categories such as cognition, endurance, and gut health. This reorganization aims to simplify complex data, making it more accessible and actionable for users. Dr. Blander highlights how these changes help users focus on the most critical health areas, guided by clear, data-driven recommendations.The conversation also touches on the impact of real-life data from InsideTracker’s extensive user base. Dr. Blander shares fascinating insights, such as the relationship between sleep duration and cardiometabolic markers, and the influence of genetics on health outcomes. He underscores the importance of prevention, citing examples like early intervention in cardiovascular health and the benefits of maintaining a healthy weight and muscle mass for longevity. The episode concludes with a discussion on the growing trend of at-home testing, highlighting its convenience and potential for expanding preventive health measures. Episode highlightsThe Importance of Metabolic Health 00:12:35Rise of At-Home Testing 00:15:49Prevention as a Strategy for Longevity 0:20:39Role of Genetics in Health Optimization 00:23:53Longevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit https://hubs.li/Q02BxrGL0 for 10% off any InsideTracker plan.______________________________________Let’s Connect!Instagram - / insidetracker Twitter - / insidetracker Facebook - / insidetracker LinkedIn- / insi. .TikTok- / insidetracker_ Pinterest- / insidetrack. .Website - insidetracker.com
Give Day the Gift of Health: 15% Off InsideTracker InsideTracker 2024-06-14 | This Father's Day, give Dad the ultimate gift— more time together.InsideTracker is a personalized program that helps optimize Dad's well-being from the inside out. He'll have the tools to feel his best for years to come, so you can share many more laughs and lasting memories together. Treat him to InsideTracker and get 15% off with code DADDAY15. Because what Dad really wants is more quality time with his loved ones! InsideTracker.com/store
Conversations about Preventative Healthcare, Balance, and Social Impact with Joe Holder InsideTracker 2024-06-13 | Renee Deehan, VP of Science and AI at InsideTracker sits down with Joe Holder to discuss his views on preventative healthcare, the value of blood testing, and how we can all band together as a society to get healthier. The conversation starts by unpacking his progressive upbringing, experience with football injuries, and development of his "OCHO" human performance system. Joe also dives into value of blood testing from InsideTracker for personalized health optimization, strategies for managing stress and recovery, and the importance of building a team of experts around you. Holder also explores the unique considerations around race and ethnicity as they impact specific health markers. Finally, he emphasizes taking honest self-inventory, overcoming willpower challenges through habits, and the potential impacts of weight-loss medications and preventative healthcare ecosystems. 00:00 - 00:44: Introduction and background on Joe Holder00:45 - 10:09 Joe's progressive upbringing and influence from his parents10:10 - 11:40: Joe's experience at the University of Pennsylvania and football injuries11:41 - 17:06 Development of the "OCHO" system 17:07 - 21:41: Why Joe chose to pursue a non-traditional career path after college21:42 - 24:29: Embracing the small steps of progress24:30 - 27:34: Value of blood testing and preventative health measures27:35 - 30:24: Why men need to prioritize their health and wellness30:25 - 33:01: Joe's approach to looking at his health markers and blood results 33:02 - 34:34: What Joe pays the most attention to on his InsideTracker test 34:35 - 38:58 : Identifying stress as a key factor influencing health markers38:59 - 41:16: Key strategies for incorporating pauses and rest into daily routines41:17 - 42:28: How Joe structures his daily routine for maximum productivity and balance 42:29 - 44:21: How reflecting on your day's experiences each night can better prepare your for the next day44:22 - 50:08: How Joe uses blood test results for his personal health and coaching clients50:09 - 55:57 Importance of building a team of experts rather than trying to be an expert in everything55:58 - 59:52: Exploring the distinction between race, ethnicity, and ancestry, and how they relate to biomarkers and access to healthcare59:53 - 1:04:42: Importance of taking an honest look at oneself and avoiding excuses.1:04:43 - 1:07:15: - Strategies for overcoming lack of willpower and developing healthy habits1:07:16 - 1:09:27: Mastering the art of recovery1:09:28 - 1:12:47: Impact of finding the right workout partners 1:12:48 - 1:19:14: Joe’s "Man versus Horse" race1:19:15 - 1:26:25: How Joe uses InsideTracker’s analysis to improve his health 1:26:26 - 1:30:10: The potential societal impact of weight-loss medications like Ozempic 1:30:11 - 1:39:17 The importance of building a preventative healthcare ecosystem in the United States 1:39:18- 1:44:02 Building a health and wellness community to create change ______________________________________Let’s Connect!Instagram - instagram.com/insidetrackerTwitter - twitter.com/InsideTrackerFacebook - facebook.com/InsideTrackerLinkedIn- https://www.linkedin.com/company/insi...TikTok- tiktok.com/@insidetracker_ Pinterest- https://www.pinterest.com/insidetrack...Website - insidetracker.com In the Press - https://www.insidetracker.com/press-p...
Understanding Aging to Extend Healthspan and Longevity with Dr. Gordon Lithgow InsideTracker 2024-06-12 | In this episode of Longevity by Design, hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander sit down with Dr. Gordon Lithgow, a Professor and Vice President for Academic Affairs at the Buck Institute for Research on Aging. Dr. Lithgow's research focuses on understanding the mechanisms of aging and identifying genes and small molecules that can prolong lifespan. With a background in genetics from the University of Glasgow and extensive experience in biotechnology and aging research, Dr. Lithgow shares his journey from growing up in Scotland to leading a lab at the Buck Institute.Dr. Lithgow discusses the compelling nature of aging as a profound biological mystery, which drew him into the field. He highlights his lab's approach of following curiosity-driven research, often using the nematode worm C. elegans as a model organism due to its short lifespan and genetic similarities to humans. This unbiased method has led to significant discoveries, including genetic mutations and drug-like molecules that extend lifespan. The conversation also covers the concept of geroscience, which Dr. Lithgow helped coin, emphasizing the link between aging and chronic diseases. A major focus of Dr. Lithgow’s work is studying protein homeostasis, which declines with age. Protein misfolding is implicated in many age-related diseases; that discovery moved the lab’s focus from lifespan extension to efforts to understand drivers of healthspan and the causes of age-related chronic diseases, in particular Alzheimer’s and Parkinson’s. His work also includes the influence of environmental factors, such as mild heat stress, and dietary iron, vitamin D, and alpha-ketoglutarate (AKG) on aging. Dr. Lithgow's interdisciplinary collaborations aim to uncover new interventions to extend healthspan and longevity.Introduction: 00:00-02:42What led Dr. Gordon Lithgow to become a scientist and research the biology of aging?: 02:43-06:20Why are worms (C.-elegans) a good model for studying aging?: 06:21-07:55Why did Dr. Gordon Lithgow transition from research investigating ways for extending lifespan to extending healthspan?: 07:56-09:24What specific diseases is Dr. Gordon Lithgow researching?: 09:25-12:01What does protein shape mean for aging?: 12:02-13:12How does mild heat stress impact health and aging?: 13:13-16:35How does vitamin D and alpha-ketoglutarate (AKG) impact aging, healthspan, and lifespan?: 16:36-25:26How does dietary iron impact aging, healthspan, and lifespan?: 25:27-29:57Are there more genes and proteins to be discovered that influence aging, or have they all been discovered?: 29:58-34:12What compound does Dr. Gordon Lithgow think has the most potential for extending healthspan and lifespan?: 34:13-35:54What is the impact of calorie restriction and exercise on healthspan and lifespan in humans?: 35:55-38:51What is the importance of clinical trials for aging research?: 38:52-42:09What are the future directions of Dr. Gordon Lithgow’s research?: 42:10-43:38Dr. Gordon Lithgow’s top tip for living healthier longer?: 43:39-48:49Longevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit https://hubs.li/Q02BxrGL0 for 10% off any InsideTracker plan.______________________________________Let’s Connect!Instagram - instagram.com/insidetrackerTwitter - twitter.com/InsideTrackerFacebook - facebook.com/InsideTrackerLinkedIn- https://www.linkedin.com/company/insi...TikTok- tiktok.com/@insidetracker_ Pinterest- https://www.pinterest.com/insidetrack...Website - insidetracker.com In the Press - https://www.insidetracker.com/press-p...
Ken Rideouts Advice to His Younger Self InsideTracker 2024-06-08 | What advice would you give to your younger self? ⬇️
The role of mTOR in Longevity InsideTracker 2024-06-04 | This clip is from an episode of Longevity By Design with co-hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, and our guest, Dr. Keith Baar. As the head of the Functional Molecular Biology Lab at UC Davis, Dr. Baar has made groundbreaking discoveries about how exercise and nutrition influence the adaptation of muscles, tendons, and ligaments. In the full episode, they cover: What is the musculoskeletal system, and can you explain why it is so vital for health, physical function and performance, and quality of life?What is the role of mTOR in health and longevity?What is the role of rapamycin and metformin in health and longevity?Activation of mTOR by resistance exercise and proteinIs there a window of opportunity for consuming protein following exercise to increase muscle protein synthesis? Is the timing of protein consumption post-exercise important for muscle protein synthesis? Is the type of protein important for muscle protein synthesis? Is there a difference between young and older adults in how they respond to resistance exercise?What are the differences in molecular responses and longevity between resistance and endurance exercise?What are ligaments and tendons? Are there differences in ligaments and tendons between men and women? What is the best way to exercise for tendons and ligaments?Is there a difference between pre-menopausal and post-menopausal women in tendons and ligaments?Why is collagen important for tendons and ligaments?Why is vitamin C important for collagen synthesis and tendons and ligaments?When should a collagen supplement be consumed?What are some misconceptions about tendons and ligaments?What happens to tendons and ligaments during a joint replacement?What excites or interests Dr. Keith Baar the most that has the potential to extend healthspan in the next 5-10 years?Full episode: youtu.be/EQEEYh6gOtQ______________________________________Let’s Connect!Instagram - instagram.com/insidetrackerTwitter - twitter.com/InsideTrackerFacebook - facebook.com/InsideTrackerLinkedIn- https://www.linkedin.com/company/insi...TikTok- tiktok.com/@insidetracker_ Pinterest- https://www.pinterest.com/insidetrack...Website - insidetracker.com In the Press - https://www.insidetracker.com/press-p...
What your body is trying to tell you InsideTracker 2024-06-02 | Often times, we ignore these signs from our body and assume we're just feeling this way because we're busy, stressed, and have a lot going on. But the truth is, your body is trying to communicate with you. Taking a look at what's going on inside is the best way to know what your body truly needs, instead of just guessing. With InsideTracker, you get a comprehensive look at nearly 50 biomarkers, and healthspan scores to understand how you're doing in 10 key areas of your health. But best of all? You get science-backed recommendations that are personalized to your body's needs, so you know exactly what to do next to start feeling your best. Ready to take control of your health? Get started: https://hubs.li/Q02wry590
Can DNA Damage be Repaired? InsideTracker 2024-06-01 | This clip is from an episode of Longevity by Design. Host Dr. Gil Blander is joined by Dr. Morten Scheibye-Knudsen, a leading figure in aging research. Dr. Scheibye-Knudsen discusses his groundbreaking research on the role of DNA damage in the aging process and its implications for chronic diseases, aging research, and longevity medicine. The goal of his work is to discover interventions leading to healthier, happier, and more productive lives.In the full episode, they cover:What is DNA damage, and what causes it?What do we know about the influence of DNA damage on aging and age-related diseases?Can DNA damage be repaired?What questions are your research group asking to better understand DNA damage and repair and their effects on aging?What is NAD, and why is it relevant to aging and age-related diseases?What are the benefits and risks of NR and NMN supplements in humans?What is a ketogenic diet? What are the effects of a ketogenic diet or ketones on DNA damage or repair and aging?What is the effect of a ketogenic diet on cancer?What is the Aging Research and Drug Discovery (ARDD) conference and its mission?What are the most prevalent features of aging?Are there differences in aging between females and males?Are there differences in tissue aging trajectories?Identifying compounds that target agingCan nuclear morphology predict cellular senescence and cancer?What is longevity medicine, and why it is so important for physicians?What pharmaceutical drugs are the most promising for targeting aging to extend human healthspan and lifespan?How important are lifestyle factors such as nutrition, physical activity and exercise, sleep, and social engagement and connections for human healthspan and lifespan?:Dr. Morten Scheibye-Knudsen’s top tip for improving healthFull episode: youtu.be/QHrrxXxl2Bk______________________________________Let’s Connect!Instagram - instagram.com/insidetrackerTwitter - twitter.com/InsideTrackerFacebook - facebook.com/InsideTrackerLinkedIn- https://www.linkedin.com/company/insi...TikTok- tiktok.com/@insidetracker_Pinterest- https://www.pinterest.com/insidetrack...Website - insidetracker.comIn the Press - https://www.insidetracker.com/press-p...
Vegan Garlic Herb Cream Sauce InsideTracker 2024-05-30 | Looking for a healthy alternative to traditional cream sauces? Give this one a try on your next pasta dish!Ingredients:1 cup cashews soaked in 1 cup hot water1/2 cup fresh basil (loosely packed)1/2 cup fresh parsley (loosely packed)3 tbsp lemon juice1 large garlic clove (1-2 small)¼ tsp sea salt or to taste¼ tsp ground pepper or to tasteInstructions:- Soak cashews in hot water in a small bowl for at least 20 minutes.- Combine all ingredients (including the water the cashews were soaked in) in a high-speed blender until smooth.- Taste and adjust seasoning and ingredients as desired.Enjoy!
The Best Time to Consume Protein After a Workout InsideTracker 2024-05-30 | This clip is from an episode of Longevity By Design with co-hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, and our guest, Dr. Keith Baar. As the head of the Functional Molecular Biology Lab at UC Davis, Dr. Baar has made groundbreaking discoveries about how exercise and nutrition influence the adaptation of muscles, tendons, and ligaments. In the full episode, they cover: What is the musculoskeletal system, and can you explain why it is so vital for health, physical function and performance, and quality of life?What is the role of mTOR in health and longevity?What is the role of rapamycin and metformin in health and longevity?Activation of mTOR by resistance exercise and proteinIs there a window of opportunity for consuming protein following exercise to increase muscle protein synthesis? Is the timing of protein consumption post-exercise important for muscle protein synthesis? Is the type of protein important for muscle protein synthesis? Is there a difference between young and older adults in how they respond to resistance exercise?What are the differences in molecular responses and longevity between resistance and endurance exercise?What are ligaments and tendons? Are there differences in ligaments and tendons between men and women? What is the best way to exercise for tendons and ligaments?Is there a difference between pre-menopausal and post-menopausal women in tendons and ligaments?Why is collagen important for tendons and ligaments?Why is vitamin C important for collagen synthesis and tendons and ligaments?When should a collagen supplement be consumed?What are some misconceptions about tendons and ligaments?What happens to tendons and ligaments during a joint replacement?What excites or interests Dr. Keith Baar the most that has the potential to extend healthspan in the next 5-10 years?Full episode: youtu.be/EQEEYh6gOtQ______________________________________Let’s Connect!Instagram - instagram.com/insidetrackerTwitter - twitter.com/InsideTrackerFacebook - facebook.com/InsideTrackerLinkedIn- https://www.linkedin.com/company/insi...TikTok- tiktok.com/@insidetracker_ Pinterest- https://www.pinterest.com/insidetrack...Website - insidetracker.com In the Press - https://www.insidetracker.com/press-p...
InsideTracker X Gainful Giveaway: $5000+ value InsideTracker 2024-05-28 | 🚨GIVEAWAY: $5,000+ value🚨InsideTracker + Gainful have teamed up to bring you a year's worth of personalized health optimization.1 lucky winner will win:- InsideTracker’s 4 Ultimates + DNA Kit- 1 year of GainfulEnter to win: https://hubs.li/Q02yJlTP0
InsideTracker X Gainful: A personalized approach to your health InsideTracker 2024-05-28 | Getting enough protein is essential for vitality today and healthspan + longevity down the road. From building muscle mass, aiding weight loss, improving metabolism and heart health, preventing frailty, and strengthening endurance, protein is essential for just about everything.But how much protein do you need? And how do you know if the protein you’re consuming is working for your unique body?Hear from Dr. Renee Deehan, SVP of Science + AI at InsideTracker, and Chris Mohr, PhD, RD and SAB Member at Gainful on personalized health. 0:00-:40 Introduction:41-4:36 What is Gainful? 4:37-5:47 The benefits of consuming enough protein 5:48-10:52 How much protein should you be eating daily? 10:53-17:48 The ideal protein timing and distribution 17:49-18:41 Can you get too much protein?18:42-20:16 Is creatine safe? What're the benefits? 20:17-21:33 The "unsung hero" of nutrition: Fiber 21:34-27:32 How protein impacts longevity27:33-33:24 Changing protein needs as you age 33:25-35:15 Protein quantity and distribution: Which matters more? 35:16- 38:05 Animal vs plant protein 38:06-39:50 How protein influences women's metabolic health 39:51- 45:47 Biomarkers associated with aging45:48-49:08 Protein Myths 49:09-54:48 InsideTracker x Gainful: Personalized solutions for better health InsideTracker analyzes your body's biomarkers, assesses where you can improve, and generates a custom Action Plan with science-backed nutrition, supplement, exercise, and lifestyle changes to help you live healthier longer.Gainful provides personalized, customizable, & curated products that help you gain more each day, no matter your goals. Shop nutrition products including personalized protein, performance greens, low sugar electrolytes and more, all with complementary expert guidance from Registered Dietitians.Learn more and enter to win our Giveaway (valued at over $5000!) insidetracker.com/gainful
