What is Random Mutation? | #EvolutionCourse | Session 2 @FindingTruthChannel
What is Random Mutation? | #EvolutionCourse | Session 2  @FindingTruthChannel
Uploaded July 2021 | Updated September 2026, 3 days ago
What are Random Mutations? And why are they such a big deal in evolutionary thinking?!
In this session we are going to learn about genetics and mutations, and understand what role mutations play in the Theory of Evolution.

Evolution is about the change of features and traits of creatures over time. But the ToE claims that those changes, on the macro level, primarily due to random events can bring about huge variation in shapes of creatures that live today versus their ancient ancestors.

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Here is the second session recording of the course "Is Evolution True or False?", titled: "What is Random Mutation?".
Already registered: Send your questions for the livestream on Saturday 10th of July, 4pm GMT.
Not registered yet, no problem, you can catch up easily, register and enroll here: findingtruthchannel.com/courses/is-evolution-true-or-false

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Contents:
1. What are phenotypes and genotypes.
2. Simplified explanation of genetic code, codons, protein synthesis.
3. DNA replication.
4. Error correction during replication: Proofreading, Mismatch repair.
5. Genetic damage repair.
6. What are Random Mutations?
7. Types of Mutations.
8. How rare is a functional protein?
9. Questioning the trans-mutational narrative in macro-evolution.

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References:
Phenotypes: nature.com/scitable/definition/phenotype-phenotypes-35

Genotypes (genome.gov/genetics-glossary/genotype

Genetic code, codons, and synonyms: ncbi.nlm.nih.gov/books/NBK22358

Mutations are mistakes: genome.gov/genetics-glossary/Mutation
A nice definition and summary about mutations: yourgenome.org/facts/what-is-a-mutation

Epigenetics: cdc.gov/genomics/disease/epigenetics.htm

Developmental Gene Regulatory Networks (dGRNs): pnas.org/content/105/51/20063

DNA to protein: nature.com/scitable/topicpage/translation-dna-to-mrna-to-protein-393

Gametes: nature.com/scitable/topicpage/replication-and-distribution-of-dna-during-meiosis-6524853

Types of Error correction: khanacademy.org/science/high-school-biology/hs-

molecular-genetics/hs-discovery-and-structure-of-dna/a/dna-proofreading-and-repair

Mutation rates in mammalian genomes: pnas.org/content/99/2/803

Estimation of functionally beneficial proteins: sciencedirect.com/science/article/abs/pii/S0022283604007624

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Videos of which excerpts were used for illustration for education purposes in the session:

This video shows the process from DNA to protein: youtu.be/gG7uCskUOrA
DNA replication: youtu.be/7Hk9jct2ozY?t=146
Proofreading: youtu.be/6O0qD6KCOV
Mismatch repair: youtu.be/p3MXIKWAi2w
damage repair/response: youtu.be/2yI_SoOWFMU

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Relevant videos from Finding Truth to expand on the discussion:

Chance and random mutations: youtu.be/iF_ZjUtMbE8
Can random mutation cause evolution: youtu.be/ZIeLieLFRgI
On Evolution series: Interview about Random Mutation: youtu.be/c9j0P4wtHSo
On Evolution, Mutations with multicellularity: youtu.be/cCw_9bshQ7w
Debate about Descent w/Modification by Random Mutation: youtu.be/yrSjft-1QvA
About Cambrian Explosion: youtu.be/gv7DN6V-D_U
Session 1 of the course: youtu.be/oJ_zMztoHo4
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#EvolutionCourse #Mutation #Genetics

Watch the episode here, but don't forget to share with loved ones:
youtu.be/WkTR6j19dT0
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What is Random Mutation? | #EvolutionCourse | Session 2

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