Two-photon imaging of microglial process motility/growth before and after glutamate application @ScientificaUk

Uploaded October 2014 | Updated September 2026, 2 weeks ago

This short two-photon video clip shows changes in microglia (GFP, green) process extension motility towards neurons (YFP, red) as a result of the application of glutamate to a hippocampal brain slice. This mimics levels of glutamate in the brain after hyperactivity such as an epileptic seizure.

Courtesy of Dr Long-Jun Wu at Rutgers University, New Jersey, USA

Find out more about Dr Wu's research here:
http://wulab.cbn.rutgers.edu

Two-photon imaging of microglial process motility/growth before and after glutamate application

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