Uploaded September 2025 | Updated September 2026, 3 weeks ago
My guest is Dr. Michael Snyder, PhD, professor of genetics at Stanford and an expert in understanding why people respond differently to various foods, supplements, behavioral and prescription interventions. We discuss how to optimize your health and lifespan according to what type of glucose responder you are, which genes you express, your lifestyle and other factors. Dr. Snyder also explains the key ages when you need to be particularly mindful about following certain health practices. We also discuss how people respond in opposite ways to different fiber types. This episode ought to be of interest and use to anyone seeking to understand their unique biological needs and how to go about meeting those needs.
Episode show notes: go.hubermanlab.com/yQHG6sg
*Thank you to our sponsors*
AGZ by AG1: drinkag1.com/huberman
Wealthfront*: wealthfront.com/huberman
David: davidprotein.com/huberman
Eight Sleep: eightsleep.com/huberman
Function: functionhealth.com/huberman
_*This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27, 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer._
*Follow Huberman Lab*
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Threads: threads.net/@hubermanlab
X: twitter.com/hubermanlab
Facebook: facebook.com/hubermanlab
TikTok: tiktok.com/@hubermanlab
LinkedIn: linkedin.com/in/andrew-huberman
Website: hubermanlab.com
Newsletter: hubermanlab.com/newsletter
*Dr. Michael Snyder*
Stanford academic profile: https://med.stanford.edu/snyderlab/about.html
Lab website: https://med.stanford.edu/snyderlab.html
AI Longevity Lab: eventbrite.com/e/stanford-genetics-department-ai-longevity-lab-certificate-tickets-1641608327699
Book: amzn.to/4m3ILuM
X: https://x.com/snydershot
LinkedIn: linkedin.com/in/mpsnyder1
Facebook: facebook.com/snyder.labs
YouTube: youtube.com/playlist?list=PLNId-2r6JNxEHXqJXqsbe_h3RnZuBlfe5
*Timestamps*
00:00:00 Michael Snyder
00:03:33 Healthy Glucose Range, Continuous Glucose Monitors (CGM), Hemoglobin A1c
00:09:02 Individual Variability & Food Choice, Glucose Spikes & Sleepiness
00:12:18 Sponsors: AGZ by AG1 & Wealthfront
00:15:16 Glucose Spikes, Tools: Post-Meal Brisk Walk; Soleus “Push-Ups”; Exercise Snacks
00:21:06 Glucose Dysregulation, Diabetes & Sub-Phenotypes, Tool: Larger Morning Meal
00:28:34 Exercise Timing, Muscle Insulin Resistance
00:30:49 Diabetes Subtyping, Weight, Glucose Control; Incretins
00:35:41 GLP-1 Agonists, Diabetes, Tool: Muscle Maintenance & Resistance Training
00:38:40 Metformin, Berberine, Headaches
00:41:01 GLP-1 Agonists, Cognition, Longevity, Tool: Habits Support Medication; Cycling
00:47:41 Subcutaneous vs Visceral Fat, Organ Stress
00:49:10 Sponsors: David & Eight Sleep
00:51:58 Meal Timing & Sleep, Tools: Post-Dinner Walk, Routines, Bedtime Consistency
00:57:16 Microbiome, Immune System & Gut; Diet & Individual Variability
01:02:52 Fiber Types, Cholesterol & Glucose, Polyphenols
01:09:50 Food As Medicine; Fiber, Microbiome & Individual Variability; Probiotics
01:18:48 Sponsor: Function
01:20:35 Profiling Healthy Individuals, Genomes, Wearables
01:26:31 Whole-Body MRIs, Nodules, Healthy Baseline, Early Diagnosis
01:34:07 Sensors, CGM, Sleep, Heart Rate Variability (HRV), Tools: Mindset Effects, Increase REM
01:39:30 HRV, Sleep, Exercise, Tool: Long Exhales; Next-Day Excitement & Sleep
01:42:48 Organ Aging, “Ageotypes”; Biological Age vs Chronological Age
01:49:41 Longevity, Health Span, Genetics, Blue Zones
01:52:19 Epigenetics, Viral Infection & Disease
01:58:54 ALS, Heritability; Neuroprotection, Nicotine
02:03:47 Air Quality, Allergies, DEET & Pesticides, Inflammation, Mold; Microplastics
02:15:02 Single-Drop Blood Test & Biomarkers, Wearables, Observational Trials
02:20:33 Acupuncture, Blood Pressure
02:26:40 Immersive Events & Mental Health Benefits
02:34:59 Data, Nutrition & Lifestyle; Siloed Health Care vs Personalized Medicine
02:43:06 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Social Media, Neural Network Newsletter
Disclaimer & Disclosures: hubermanlab.com/disclaimer
My guest is Dr. Michael Snyder, PhD, professor of genetics at Stanford and an expert in understanding why people respond differently to various foods, supplements, behavioral and prescription interventions. We discuss how to optimize your health and lifespan according to what type of glucose responder you are, which genes you express, your lifestyle and other factors. Dr. Snyder also explains the key ages when you need to be particularly mindful about following certain health practices. We also discuss how people respond in opposite ways to different fiber types. This episode ought to be of interest and use to anyone seeking to understand their unique biological needs and how to go about meeting those needs.
Episode show notes: go.hubermanlab.com/yQHG6sg
*Thank you to our sponsors*
AGZ by AG1: drinkag1.com/huberman
Wealthfront*: wealthfront.com/huberman
David: davidprotein.com/huberman
Eight Sleep: eightsleep.com/huberman
Function: functionhealth.com/huberman
_*This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27, 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer._
*Follow Huberman Lab*
Instagram: instagram.com/hubermanlab
Threads: threads.net/@hubermanlab
X: twitter.com/hubermanlab
Facebook: facebook.com/hubermanlab
TikTok: tiktok.com/@hubermanlab
LinkedIn: linkedin.com/in/andrew-huberman
Website: hubermanlab.com
Newsletter: hubermanlab.com/newsletter
*Dr. Michael Snyder*
Stanford academic profile: https://med.stanford.edu/snyderlab/about.html
Lab website: https://med.stanford.edu/snyderlab.html
AI Longevity Lab: eventbrite.com/e/stanford-genetics-department-ai-longevity-lab-certificate-tickets-1641608327699
Book: amzn.to/4m3ILuM
X: https://x.com/snydershot
LinkedIn: linkedin.com/in/mpsnyder1
Facebook: facebook.com/snyder.labs
YouTube: youtube.com/playlist?list=PLNId-2r6JNxEHXqJXqsbe_h3RnZuBlfe5
*Timestamps*
00:00:00 Michael Snyder
00:03:33 Healthy Glucose Range, Continuous Glucose Monitors (CGM), Hemoglobin A1c
00:09:02 Individual Variability & Food Choice, Glucose Spikes & Sleepiness
00:12:18 Sponsors: AGZ by AG1 & Wealthfront
00:15:16 Glucose Spikes, Tools: Post-Meal Brisk Walk; Soleus “Push-Ups”; Exercise Snacks
00:21:06 Glucose Dysregulation, Diabetes & Sub-Phenotypes, Tool: Larger Morning Meal
00:28:34 Exercise Timing, Muscle Insulin Resistance
00:30:49 Diabetes Subtyping, Weight, Glucose Control; Incretins
00:35:41 GLP-1 Agonists, Diabetes, Tool: Muscle Maintenance & Resistance Training
00:38:40 Metformin, Berberine, Headaches
00:41:01 GLP-1 Agonists, Cognition, Longevity, Tool: Habits Support Medication; Cycling
00:47:41 Subcutaneous vs Visceral Fat, Organ Stress
00:49:10 Sponsors: David & Eight Sleep
00:51:58 Meal Timing & Sleep, Tools: Post-Dinner Walk, Routines, Bedtime Consistency
00:57:16 Microbiome, Immune System & Gut; Diet & Individual Variability
01:02:52 Fiber Types, Cholesterol & Glucose, Polyphenols
01:09:50 Food As Medicine; Fiber, Microbiome & Individual Variability; Probiotics
01:18:48 Sponsor: Function
01:20:35 Profiling Healthy Individuals, Genomes, Wearables
01:26:31 Whole-Body MRIs, Nodules, Healthy Baseline, Early Diagnosis
01:34:07 Sensors, CGM, Sleep, Heart Rate Variability (HRV), Tools: Mindset Effects, Increase REM
01:39:30 HRV, Sleep, Exercise, Tool: Long Exhales; Next-Day Excitement & Sleep
01:42:48 Organ Aging, “Ageotypes”; Biological Age vs Chronological Age
01:49:41 Longevity, Health Span, Genetics, Blue Zones
01:52:19 Epigenetics, Viral Infection & Disease
01:58:54 ALS, Heritability; Neuroprotection, Nicotine
02:03:47 Air Quality, Allergies, DEET & Pesticides, Inflammation, Mold; Microplastics
02:15:02 Single-Drop Blood Test & Biomarkers, Wearables, Observational Trials
02:20:33 Acupuncture, Blood Pressure
02:26:40 Immersive Events & Mental Health Benefits
02:34:59 Data, Nutrition & Lifestyle; Siloed Health Care vs Personalized Medicine
02:43:06 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Social Media, Neural Network Newsletter
Disclaimer & Disclosures: hubermanlab.com/disclaimer
