Uploaded December 2025 | Updated September 2026, 2 weeks ago
Dr. Ryan Vandrey is a professor of Psychiatry and Behavioral Sciences at John’s Hopkins. Dr. Johannes Thrul is an Associate Professor at John’s Hopkins.
They both work for the Cannabis Health & Research Initiative, which is a collaboration between two organizations with years of experience in medicinal cannabis research: Johns Hopkins University and Realm of Caring. Simply put, CHRI is a platform of data collection and dissemination focused on the health outcomes of medicinal cannabis at the patient level, and they have created a number of valuable resources to help cannabis medicine researchers, including:
- A data repository that contains de-identified data collected through CHRI
- Research Library that contains more than 3000 published scientific articles related to the health effects of cannabis
- A set of validated questionnares that clinicians can use when speaking to patients about cannabis
- and more
The CHRI is also currently recruiting participants for their National Cannabis Study, which is a collection of firsthand experiences with medicinal cannabis among individuals with various health conditions. Specifically, they are looking for participants who plan to use cannabis but have not yet started cannabis use. So if that’s you or someone you know, we highly suggest you consider participating in the study because the research has the potential to impact best practices in healthcare and the cannabis industry.
During our conversation, Ryan and Johannes shared more details about the CHRI and the National Cannabis Study, and I think you will agree that their mission aligns perfectly with the CannMed Community.
Thanks to This Episode's Sponsor: Realm of Caring
Founded in 2013, Realm of Caring (RoC) serves anyone in need of more information about cannabinoid therapies. Through revolutionary CBD and Cannabis research, innovative education, and life-changing grants, RoC seeks to facilitate and encourage the mainstream acceptance of transformative, plant powered therapies to benefit individuals and families and serve healthcare providers as well as the hemp and cannabis industries.
Learn more at RealmofCaring.org
Additional Resources
- Cannabis Health Research Initiative website - cannabisandhealth.org
Dr. Ryan Vandrey is a professor of Psychiatry and Behavioral Sciences at John’s Hopkins. Dr. Johannes Thrul is an Associate Professor at John’s Hopkins.
They both work for the Cannabis Health & Research Initiative, which is a collaboration between two organizations with years of experience in medicinal cannabis research: Johns Hopkins University and Realm of Caring. Simply put, CHRI is a platform of data collection and dissemination focused on the health outcomes of medicinal cannabis at the patient level, and they have created a number of valuable resources to help cannabis medicine researchers, including:
- A data repository that contains de-identified data collected through CHRI
- Research Library that contains more than 3000 published scientific articles related to the health effects of cannabis
- A set of validated questionnares that clinicians can use when speaking to patients about cannabis
- and more
The CHRI is also currently recruiting participants for their National Cannabis Study, which is a collection of firsthand experiences with medicinal cannabis among individuals with various health conditions. Specifically, they are looking for participants who plan to use cannabis but have not yet started cannabis use. So if that’s you or someone you know, we highly suggest you consider participating in the study because the research has the potential to impact best practices in healthcare and the cannabis industry.
During our conversation, Ryan and Johannes shared more details about the CHRI and the National Cannabis Study, and I think you will agree that their mission aligns perfectly with the CannMed Community.
Thanks to This Episode's Sponsor: Realm of Caring
Founded in 2013, Realm of Caring (RoC) serves anyone in need of more information about cannabinoid therapies. Through revolutionary CBD and Cannabis research, innovative education, and life-changing grants, RoC seeks to facilitate and encourage the mainstream acceptance of transformative, plant powered therapies to benefit individuals and families and serve healthcare providers as well as the hemp and cannabis industries.
Learn more at RealmofCaring.org
Additional Resources
- Cannabis Health Research Initiative website - cannabisandhealth.org




![How Would Rescheduling THC to Schedule III Impact Clinical Trials?
Dr. Emily Lindley is Assistant Professor of Orthopedics and Director of the Colorado Cannabis Research Consortium. Her team’s research aims to identify non-opioid alternatives for the treatment of chronic musculoskeletal pain. One such alternative that has gained increased recognition in recent years is medical cannabis, and her lab is currently studying the health effects of cannabis and cannabinoids for chronic musculoskeletal pain.
Dr. Rachael Rzasa Lynn is a board certified in pain medicine physician and is an Associate Professor in the Department of Anesthesiology at the University of Colorado, where she is the Associate Program Director for the Pain Medicine Fellowship. Her research includes investigations in opioid pharmacology and the use of cannabis for chronic pain.
Rachel and Emily co-authored a poster presented at the most recent ICRS conference titled, Recruitment Challenges in Clinical Studies of Cannabis
During our conversation, we discussed:
* How recruitment for cannabis clinical trials differs from traditional clinical trials
* Why prior experience with cannabis is considered a negative for patient recruitment
* How legal concerns and stigma can deter cannabis-naive patients from enrolling
* Why the participant drop out rate is higher in cannabis trials
* How rescheduling may affect patient recruitment for future trials
Thanks to This Episodes Sponsor: The Society of Cannabis Clinicians
The Society of Cannabis Clinicians’ Med Cann conference offers a rare opportunity for clinicians to dive deep into the clinical realities and therapeutic potential of medical cannabis and psychedelics. Designed with healthcare providers in mind, their sessions focus on case-based learning, emerging protocols, and real-world challenges—offering practical insights that can be immediately applied in your practice.
Learn more at cannabisclinicians.org and use code CP15 to receive 15% Off Your Registration
Additional Resources
* Recruitment Challenges in Clinical Studies of Cannabis [Poster] - https://cannmedevents.com/wp-content/uploads/2025/08/P2-21-Recruitment-Challenges-Poster-ICRS-2025.pdf
* Lindley Lab at the University of Colorado - https://medschool.cuanschutz.edu/orthopedics/research/labs/lindley-lab/our-research How Would Rescheduling THC to Schedule III Impact Clinical Trials?](https://i.ytimg.com/vi/UgSaRtD9l7w/mqdefault.jpg)





