Uploaded July 2025 | Updated September 2026, 2 weeks ago
This conversation with Dr. Paul Saladino is a call to investigate the why behind our habits, our headlines, and our health beliefs. In a world full of fear-based marketing—from sunscreens to snack bars—his perspective invites a more grounded perspective rooted in science.
Paul doesn’t just challenge the status quo, he brings data, ancestral wisdom, and personal experience to illuminate what’s actually making us sick.
Tune in to the full episode to learn more about:
- The real cause of skin cancer (and why sunlight isn’t the villain)
- How seed oils impact your skin
- Why sunglasses may increase your risk of sun damage
- Why Paul started eating fruit after 1.5 years on a carnivore diet
- The problem with vegetables
- Why indoor lighting may be ruining your nervous system
- The benefits of creatine
- Why your “healthy” snack bar is wrecking your hormones and gut health
If you’ve ever wondered why doing “all the right things” still leaves you tired, inflamed, or confused—this conversation might hold the answers.
Enjoy 15% off clean, high-protein, nutrient-dense meat snacks and supplements made from real, regeneratively raised ingredients with code: GROUNDEDWELLNESS
Shop Lineage Provisions: bit.ly/46wvZRa
Episode Resources:
Paul Saladino:
Website: paulsaladinomd.co
Newsletter sign-up & Other resources: paulsaladinomd.co/resources
Instagram: instagram.com/paulsaladinomd
X: https://x.com/paulsaladinomd
TikTok: tiktok.com/@paulsaladinomd2
YouTube: youtube.com/@Paulsaladinomd/featured
LinkedIn: linkedin.com/company/paulsaladinomd
Explore more from Primally Pure:
Shop: bit.ly/4e1HzVv
Blog: bit.ly/4gAeIsY
Instagram: instagram.com/primallypure
TikTok: tiktok.com/@primallypure?lang=en
Studies Paul references in this episode:
Outdoor workers show lower melanoma rates than indoor workers pubmed.ncbi.nlm.nih.gov/16734890 - pubmed.ncbi.nlm.nih.gov/2256710
Higher linoleic acid levels are linked with increased melanoma risk. pubmed.ncbi.nlm.nih.gov/16372927 - pubmed.ncbi.nlm.nih.gov/3110746
High‑linoleic (n‑6 PUFA) diets exacerbate UV‑induced skin cancers in animal models; notably PUFA-fed mice showed greater UV tumorigenesis than those fed saturated fats pmc.ncbi.nlm.nih.gov/articles/PMC6035072/?utm_source=chatgpt.com
UV exposure induces peroxidation of linoleic acid in the stratum corneum, triggering inflammation mdpi.com/2079-9284/12/4/130?utm_source=chatgpt.com
Diets high in linoleic acid lead to greater incorporation into LDL and enhance LDL oxidizability, a well-established atherogenic risk factor pubmed.ncbi.nlm.nih.gov/9488997 , pubmed.ncbi.nlm.nih.gov/1558840
Potatoes fried in seed oils carry the same amount of chemicals found in 25 cigarettes pmc.ncbi.nlm.nih.gov/articles/PMC6131264
Sucralose & hypothalamic blood flow pubmed.ncbi.nlm.nih.gov/40140714
Quorum sensing disruption in the microbiome from artificial sweeteners pubmed.ncbi.nlm.nih.gov/34576027
Monkeys Study: Indicates faster turnover with low-fat diets, suggesting possible acceleration strategies.https://link.springer.com/article/10.1007/BF02523831 onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.1990.tb03125.x
Kinetic Study: Suggests it may take 2+ years to fully turn over polyunsaturated fats in cell membranes. pmc.ncbi.nlm.nih.gov/articles/PMC10386285, pubmed.ncbi.nlm.nih.gov/5900208
Chapters
00:00 Introduction to Paul Saladino
01:55 The Controversy of Sun Exposure and Sunscreen
11:56 Understanding Light: Natural vs. Artificial
18:02 Debunking Myths: Sun Exposure and Skin Cancer
39:05 Weight Loss: The Role of Quality Over Quantity
48:50 Navigating Processed Foods and Convenience
58:00 The Journey to Detox from Processed Foods
01:00:23 Rethinking Vegetables: A Nutritional Perspective
01:04:57 The Power of Liver: Nutritional Insights
01:07:58 Bioindividuality in Diet: Finding What Works for You
01:13:16 Dietary Choices: Balancing Animal and Plant Foods
01:14:43 Exploring Commonly Accepted Substances: Coffee and Alcohol
01:18:56 The Impact of Microplastics: A Growing Concern
01:29:37 Creatine: The Overlooked Nutrient
01:34:33 Practical Health Tips: Simple Changes for Better Living
This conversation with Dr. Paul Saladino is a call to investigate the why behind our habits, our headlines, and our health beliefs. In a world full of fear-based marketing—from sunscreens to snack bars—his perspective invites a more grounded perspective rooted in science.
Paul doesn’t just challenge the status quo, he brings data, ancestral wisdom, and personal experience to illuminate what’s actually making us sick.
Tune in to the full episode to learn more about:
- The real cause of skin cancer (and why sunlight isn’t the villain)
- How seed oils impact your skin
- Why sunglasses may increase your risk of sun damage
- Why Paul started eating fruit after 1.5 years on a carnivore diet
- The problem with vegetables
- Why indoor lighting may be ruining your nervous system
- The benefits of creatine
- Why your “healthy” snack bar is wrecking your hormones and gut health
If you’ve ever wondered why doing “all the right things” still leaves you tired, inflamed, or confused—this conversation might hold the answers.
Enjoy 15% off clean, high-protein, nutrient-dense meat snacks and supplements made from real, regeneratively raised ingredients with code: GROUNDEDWELLNESS
Shop Lineage Provisions: bit.ly/46wvZRa
Episode Resources:
Paul Saladino:
Website: paulsaladinomd.co
Newsletter sign-up & Other resources: paulsaladinomd.co/resources
Instagram: instagram.com/paulsaladinomd
X: https://x.com/paulsaladinomd
TikTok: tiktok.com/@paulsaladinomd2
YouTube: youtube.com/@Paulsaladinomd/featured
LinkedIn: linkedin.com/company/paulsaladinomd
Explore more from Primally Pure:
Shop: bit.ly/4e1HzVv
Blog: bit.ly/4gAeIsY
Instagram: instagram.com/primallypure
TikTok: tiktok.com/@primallypure?lang=en
Studies Paul references in this episode:
Outdoor workers show lower melanoma rates than indoor workers pubmed.ncbi.nlm.nih.gov/16734890 - pubmed.ncbi.nlm.nih.gov/2256710
Higher linoleic acid levels are linked with increased melanoma risk. pubmed.ncbi.nlm.nih.gov/16372927 - pubmed.ncbi.nlm.nih.gov/3110746
High‑linoleic (n‑6 PUFA) diets exacerbate UV‑induced skin cancers in animal models; notably PUFA-fed mice showed greater UV tumorigenesis than those fed saturated fats pmc.ncbi.nlm.nih.gov/articles/PMC6035072/?utm_source=chatgpt.com
UV exposure induces peroxidation of linoleic acid in the stratum corneum, triggering inflammation mdpi.com/2079-9284/12/4/130?utm_source=chatgpt.com
Diets high in linoleic acid lead to greater incorporation into LDL and enhance LDL oxidizability, a well-established atherogenic risk factor pubmed.ncbi.nlm.nih.gov/9488997 , pubmed.ncbi.nlm.nih.gov/1558840
Potatoes fried in seed oils carry the same amount of chemicals found in 25 cigarettes pmc.ncbi.nlm.nih.gov/articles/PMC6131264
Sucralose & hypothalamic blood flow pubmed.ncbi.nlm.nih.gov/40140714
Quorum sensing disruption in the microbiome from artificial sweeteners pubmed.ncbi.nlm.nih.gov/34576027
Monkeys Study: Indicates faster turnover with low-fat diets, suggesting possible acceleration strategies.https://link.springer.com/article/10.1007/BF02523831 onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.1990.tb03125.x
Kinetic Study: Suggests it may take 2+ years to fully turn over polyunsaturated fats in cell membranes. pmc.ncbi.nlm.nih.gov/articles/PMC10386285, pubmed.ncbi.nlm.nih.gov/5900208
Chapters
00:00 Introduction to Paul Saladino
01:55 The Controversy of Sun Exposure and Sunscreen
11:56 Understanding Light: Natural vs. Artificial
18:02 Debunking Myths: Sun Exposure and Skin Cancer
39:05 Weight Loss: The Role of Quality Over Quantity
48:50 Navigating Processed Foods and Convenience
58:00 The Journey to Detox from Processed Foods
01:00:23 Rethinking Vegetables: A Nutritional Perspective
01:04:57 The Power of Liver: Nutritional Insights
01:07:58 Bioindividuality in Diet: Finding What Works for You
01:13:16 Dietary Choices: Balancing Animal and Plant Foods
01:14:43 Exploring Commonly Accepted Substances: Coffee and Alcohol
01:18:56 The Impact of Microplastics: A Growing Concern
01:29:37 Creatine: The Overlooked Nutrient
01:34:33 Practical Health Tips: Simple Changes for Better Living
