Reactions | The Early Plan to Fight COVID with the Polio Vaccine @ACSReactions | Uploaded 4 years ago | Updated 6 minutes ago
The COVID-19 pandemic has scientists considering a few less-conventional options while vaccines against SARS-CoV-2 are being developed. One option might be the oral #polio #vaccine. We chatted with one of the researchers proposing the idea—Dr. Robert Gallo—to understand why a vaccine that hasn’t been used in the US for two decades might provide short-term protection against this #coronavirus.

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Credits:
Executive Producers:
George Zaidan
Hilary Hudson

Producers:
Andrew Sobey
Elaine Seward

Writer/Host:
Samantha Jones, PhD

Scientific consultants:
Stosh Ozog, PhD
Victor Nizet, PhD
Robert Gallo, PhD
Lelia Duman, PhD
Brianne Raccor, PhD

Special Thanks:
Ruben Rodriguez

Guard Dog:
Yuca

Sources:

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response
ncbi.nlm.nih.gov/pmc/articles/PMC7165108

Live Enteroviral Vaccines for the Emergency Nonspecific Prevention of Mass Respiratory Diseases During Fall-Winter Epidemics of Influenza and Acute Respiratory Diseases
pubmed.ncbi.nlm.nih.gov/1338742

Potential Use of Nonpathogenic Enteroviruses for Control of Human Disease pubmed.ncbi.nlm.nih.gov/2555836

Could Old Vaccines for Other Germs Protect Against COVID-19?
nytimes.com/aponline/2020/04/13/health/ap-us-med-virus-outbreak-old-vaccines.html

Could old vaccines for other germs protect against COVID-19?
apnews.com/ae72d066a2caa17de91be9a60e4934b9

Can an Old Vaccine Stop the New Coronavirus?
nytimes.com/2020/04/03/health/coronavirus-bcg-vaccine.html

Innate and adaptive immunity
creative-diagnostics.com/innate-and-adaptive-immunity.htm

Facets of Innate Immunity to Viral Infection
pubmed.ncbi.nlm.nih.gov/30307790/?from_term=innate+immunity&from_pos=1

Evolving Adaptive Immunity
pubmed.ncbi.nlm.nih.gov/27083993/?from_term=adaptive+immunity&from_pos=5

Trained Immunity: A Memory for Innate Host Defense
pubmed.ncbi.nlm.nih.gov/21575907

Vaccine Adjuvants: Putting Innate Immunity to Work
ncbi.nlm.nih.gov/pmc/articles/PMC3420356

Fundamentals of Vaccine Immunology
ncbi.nlm.nih.gov/pmc/articles/PMC3068582

Autoimmunity: From Bench to Bedside
ncbi.nlm.nih.gov/books/NBK459455

Could a 100-year-old vaccine protect against COVID-19?
livescience.com/coronavirus-protection-using-tuberculosis-vaccine.html