The Proof with Simon Hill | The #1 Blood Test to Predict Heart Attack Risk | The Proof Podcast EP #315 @TheProofWithSimonHill | Uploaded May 2024 | Updated October 2024, 2 hours ago.
What is ApoB and why should you care? In this latest instalment of our masterclass series, I’ve distilled the essential insights about apolipoprotein B (ApoB) into one informative episode. Join top experts including Dr Thomas Dayspring, Dr William Cromwell, Danny Lennon, Dr Alan Flanagan, and Dr Gil Carvalho as they unravel the significance of ApoB as a crucial marker of cardiovascular health. This episode provides a thorough understanding of why ApoB matters and how it impacts your health.
👇 Visit The Proof website for the full show notes and supporting studies. 👇 theproof.com/podcast
We cover:
00:00 Introduction
00:43 Lipoproteins & Cholesterol: Transport and Recycling
26:02 Cholesterol's Role in Lipoproteins
30:31 Is ApoB a More Accurate Marker of Cardiovascular Risk?
39:00 Endothelial Transcytosis of Lipoproteins
48:36 LDL Modification and Aggregation
55:11 Evidence for ApoB's Role in Atherosclerosis
57:56 ApoB and Genetics
1:01:54 ApoB and Longevity
1:04:49 Mechanisms Behind Elevated ApoB Levels
1:09:47 Why ApoB is the Best Predictor of Cardiovascular Disease
1:21:57 ApoB vs LDL-Cholesterol: Understanding the Discordance
1:32:36 Healthy ApoB Levels for Young Adults
1:46:13 Causes of Elevated ApoB Levels
2:05:25 Target ApoB Levels for Cardiovascular Disease Prevention
2:08:26 The History and Evolution of the Lipid Hypothesis
2:11:22 Role of ApoB Lipoproteins in Atherosclerosis
2:19:34 Importance of ApoB as a Cardiovascular Risk Marker and Its Clinical Application
2:29:15 How to Reduce ApoB Levels on a Ketogenic
2:35:20 Top Saturated Fat Foods That Increase Cardiovascular Risk
2:36:38 Impact of Saturated Fat on ApoB and Cardiovascular Disease
2:39:56 Dietary Changes to Lower ApoB Levels
This episode stands out for the exceptional calibre of scientists it features. Dr Thomas Dayspring, a Fellow of both the American College of Physicians and the National Lipid Association, is certified in internal medicine and clinical lipidology, and has delivered over 4000 lectures worldwide. Dr Alan Flanagan holds an MSc and PhD from the University of Surrey and is a renowned expert in nutrition. Dr Gil Carvalho is a respected physician and research scientist with extensive knowledge in nutrition and genetics. Dr William Cromwell, a lipidologist with over 35 years of clinical practice, brings a wealth of experience to the table. Danny Lennon, known for his expertise in interpreting the latest nutrition research, is a sought-after speaker on evidence-based nutrition. You’re in safe hands with these distinguished experts.
Learn more and connect with today’s guests:
- Dr Thomas Dayspring: theproof.com/tag/thomas-dayspring
- Dr William Cromwell: theproof.com/tag/william-cromwell
- Danny Lennon: theproof.com/tag/danny-lennon
- Dr Alan Flanagan: theproof.com/tag/alan-flanagan
- Dr Gil Carvalho: theproof.com/tag/gil-carvalho
Enjoy, friends.
Simon
This episode is brought to you by:
InsideTracker
If you want to improve your health, you need to measure where you’re currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon
Sun Home Saunas
Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to sunhomesaunas.com/theproof for $300 off your purchase.
BON CHARGE
Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill theproof.com/podcast
Author of The Proof is in the Plants theproof.com/book
Watch the episodes on YouTube youtube.com/c/TheProofWithSimonHill/videos or listen on Apple podcasts.apple.com/au/podcast/the-proof-with-simon-hill/id1367773989 Spotify open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi?si=84831dc34dc9408b
Connect with me on Instagram instagram.com/theproof/, Twitter mobile.twitter.com/theproof, and Facebook facebook.com/theproofwithsimonhill
Nourish your gut with my Plant-Based Ferments Guide theproof.com/ferments
Download my complimentary Two-Week Meal Plan plantproof.com/mealplan and high protein Plant Performance recipe book theproof.com/performance
What is ApoB and why should you care? In this latest instalment of our masterclass series, I’ve distilled the essential insights about apolipoprotein B (ApoB) into one informative episode. Join top experts including Dr Thomas Dayspring, Dr William Cromwell, Danny Lennon, Dr Alan Flanagan, and Dr Gil Carvalho as they unravel the significance of ApoB as a crucial marker of cardiovascular health. This episode provides a thorough understanding of why ApoB matters and how it impacts your health.
👇 Visit The Proof website for the full show notes and supporting studies. 👇 theproof.com/podcast
We cover:
00:00 Introduction
00:43 Lipoproteins & Cholesterol: Transport and Recycling
26:02 Cholesterol's Role in Lipoproteins
30:31 Is ApoB a More Accurate Marker of Cardiovascular Risk?
39:00 Endothelial Transcytosis of Lipoproteins
48:36 LDL Modification and Aggregation
55:11 Evidence for ApoB's Role in Atherosclerosis
57:56 ApoB and Genetics
1:01:54 ApoB and Longevity
1:04:49 Mechanisms Behind Elevated ApoB Levels
1:09:47 Why ApoB is the Best Predictor of Cardiovascular Disease
1:21:57 ApoB vs LDL-Cholesterol: Understanding the Discordance
1:32:36 Healthy ApoB Levels for Young Adults
1:46:13 Causes of Elevated ApoB Levels
2:05:25 Target ApoB Levels for Cardiovascular Disease Prevention
2:08:26 The History and Evolution of the Lipid Hypothesis
2:11:22 Role of ApoB Lipoproteins in Atherosclerosis
2:19:34 Importance of ApoB as a Cardiovascular Risk Marker and Its Clinical Application
2:29:15 How to Reduce ApoB Levels on a Ketogenic
2:35:20 Top Saturated Fat Foods That Increase Cardiovascular Risk
2:36:38 Impact of Saturated Fat on ApoB and Cardiovascular Disease
2:39:56 Dietary Changes to Lower ApoB Levels
This episode stands out for the exceptional calibre of scientists it features. Dr Thomas Dayspring, a Fellow of both the American College of Physicians and the National Lipid Association, is certified in internal medicine and clinical lipidology, and has delivered over 4000 lectures worldwide. Dr Alan Flanagan holds an MSc and PhD from the University of Surrey and is a renowned expert in nutrition. Dr Gil Carvalho is a respected physician and research scientist with extensive knowledge in nutrition and genetics. Dr William Cromwell, a lipidologist with over 35 years of clinical practice, brings a wealth of experience to the table. Danny Lennon, known for his expertise in interpreting the latest nutrition research, is a sought-after speaker on evidence-based nutrition. You’re in safe hands with these distinguished experts.
Learn more and connect with today’s guests:
- Dr Thomas Dayspring: theproof.com/tag/thomas-dayspring
- Dr William Cromwell: theproof.com/tag/william-cromwell
- Danny Lennon: theproof.com/tag/danny-lennon
- Dr Alan Flanagan: theproof.com/tag/alan-flanagan
- Dr Gil Carvalho: theproof.com/tag/gil-carvalho
Enjoy, friends.
Simon
This episode is brought to you by:
InsideTracker
If you want to improve your health, you need to measure where you’re currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon
Sun Home Saunas
Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to sunhomesaunas.com/theproof for $300 off your purchase.
BON CHARGE
Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill theproof.com/podcast
Author of The Proof is in the Plants theproof.com/book
Watch the episodes on YouTube youtube.com/c/TheProofWithSimonHill/videos or listen on Apple podcasts.apple.com/au/podcast/the-proof-with-simon-hill/id1367773989 Spotify open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi?si=84831dc34dc9408b
Connect with me on Instagram instagram.com/theproof/, Twitter mobile.twitter.com/theproof, and Facebook facebook.com/theproofwithsimonhill
Nourish your gut with my Plant-Based Ferments Guide theproof.com/ferments
Download my complimentary Two-Week Meal Plan plantproof.com/mealplan and high protein Plant Performance recipe book theproof.com/performance
