Uploaded October 2025 | Updated September 2026, 1 day ago
Viral pneumonia can cause severe lung damage and make recovery long and life-threatening for patients. Current treatments only provide support, not repair, but Northwestern Medicine scientist Benjamin Singer, MD, wants to change that.
In this episode, he details a recent discovery from his team that found laboratory-modified T-cells or induced regulatory T-cells (iTregs), can promote lung tissue repair in mice with severe influenza pneumonia. Singer discusses this breakthrough and how it could lead to an effective cellular therapy for patients with severe viral pneumonia and acute respiratory distress syndrome in the future.
01:23 Understanding Viral Pneumonia
02:24 Current Treatments and Challenges
03:57 Exploring Regulatory T Cells
06:07 Creating Induced Regulatory T Cells
07:34 The Role of UHR F1 in Treg Stability
09:32 Future Pathways and Clinical Trials
15:27 The Socrates Project: Difficult to Diagnose Team
17:42 Conclusion and Preventive Measures
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Visit the Feinberg website: https://www.feinberg.northwestern.edu/
SUBSCRIBE: spr.ly/60073dxlv
TWITTER (X): spr.ly/60003dxmj
INSTAGRAM: spr.ly/60083dxWi
FACEBOOK: spr.ly/60063dxW0
LINKEDIN: spr.ly/60063dxqG
About Northwestern University Feinberg School of Medicine in Chicago, Illinois:
Our mission is to impact the practice of medicine through discovery and education to improve human health.
Viral pneumonia can cause severe lung damage and make recovery long and life-threatening for patients. Current treatments only provide support, not repair, but Northwestern Medicine scientist Benjamin Singer, MD, wants to change that.
In this episode, he details a recent discovery from his team that found laboratory-modified T-cells or induced regulatory T-cells (iTregs), can promote lung tissue repair in mice with severe influenza pneumonia. Singer discusses this breakthrough and how it could lead to an effective cellular therapy for patients with severe viral pneumonia and acute respiratory distress syndrome in the future.
01:23 Understanding Viral Pneumonia
02:24 Current Treatments and Challenges
03:57 Exploring Regulatory T Cells
06:07 Creating Induced Regulatory T Cells
07:34 The Role of UHR F1 in Treg Stability
09:32 Future Pathways and Clinical Trials
15:27 The Socrates Project: Difficult to Diagnose Team
17:42 Conclusion and Preventive Measures
-----------------------------------------
Visit the Feinberg website: https://www.feinberg.northwestern.edu/
SUBSCRIBE: spr.ly/60073dxlv
TWITTER (X): spr.ly/60003dxmj
INSTAGRAM: spr.ly/60083dxWi
FACEBOOK: spr.ly/60063dxW0
LINKEDIN: spr.ly/60063dxqG
About Northwestern University Feinberg School of Medicine in Chicago, Illinois:
Our mission is to impact the practice of medicine through discovery and education to improve human health.
