Uploaded May 2025 | Updated September 2026, 2 weeks ago
TosMIC, Bredereck's Reagent, Eschenmoser's salt, and N-hydroxymethyl phthalimide - what do all of these reagents have in common? They are all able to do some powerful carbon-nitrogen chemistry. In this video, I discuss some of the most relevant reagents for carbon-nitrogen chemistry.
Interested in synthetic consulting? Get in touch! More info at the end of the video. Interested sponsors are also encouraged to reach out. I am basically at capacity for consulting clients at the moment, but if you have a project which you deem as interesting, still reach out - I wanna hear about it.
Important Papers covers various chemical reactions, mechanisms, and research papers in the field of organic chemistry, providing examples and explanations for each research paper.
Support the Channel on Patreon - patreon.com/thatchemist
Important Papers Playlist - youtube.com/playlist?list=PL6OLqxmk7RtyRkdJhXK8NWpT1krGNq1p4
References:
TosMIC synthesis: doi.org/10.1021/acs.joc.1c01529
TosMIC Eeros: doi.org/10.1002/047084289X.rt150.pub2
Eschenmoser's Salt Synthesis: doi.org/10.1002/anie.197103301
Eshenmoser's Salt Eeros: doi.org/10.1002/047084289X.rd346
Patent example: patents.google.com/patent/WO2022140769A1
Pyridylic Eschenmoser's addition: doi.org/10.1055/a-1916-5335
Eschenmoser's EAS - doi.org/10.1016/j.bmc.2017.07.043
Bredereck's Synthesis (part 1): doi.org/10.1021/acs.orglett.7b00793
Bredereck's Synthesis Part 2: doi.org/10.1002/cber.19681010108
(I couldn’t find one directly for the chloride, but the Eeros article implies it)
Bredereck's Eeros: doi.org/10.1002/9780470842898.rb350.pub2
N-hydroxymethylphthalimide Synthesis: doi.org/10.1002/chem.201102366
EAS of N-hydroxymethylphthalimide doi.org/10.1055/s-1993-26001
Hey you read this - that means you are now obligated to have a great day!
TosMIC, Bredereck's Reagent, Eschenmoser's salt, and N-hydroxymethyl phthalimide - what do all of these reagents have in common? They are all able to do some powerful carbon-nitrogen chemistry. In this video, I discuss some of the most relevant reagents for carbon-nitrogen chemistry.
Interested in synthetic consulting? Get in touch! More info at the end of the video. Interested sponsors are also encouraged to reach out. I am basically at capacity for consulting clients at the moment, but if you have a project which you deem as interesting, still reach out - I wanna hear about it.
Important Papers covers various chemical reactions, mechanisms, and research papers in the field of organic chemistry, providing examples and explanations for each research paper.
Support the Channel on Patreon - patreon.com/thatchemist
Important Papers Playlist - youtube.com/playlist?list=PL6OLqxmk7RtyRkdJhXK8NWpT1krGNq1p4
References:
TosMIC synthesis: doi.org/10.1021/acs.joc.1c01529
TosMIC Eeros: doi.org/10.1002/047084289X.rt150.pub2
Eschenmoser's Salt Synthesis: doi.org/10.1002/anie.197103301
Eshenmoser's Salt Eeros: doi.org/10.1002/047084289X.rd346
Patent example: patents.google.com/patent/WO2022140769A1
Pyridylic Eschenmoser's addition: doi.org/10.1055/a-1916-5335
Eschenmoser's EAS - doi.org/10.1016/j.bmc.2017.07.043
Bredereck's Synthesis (part 1): doi.org/10.1021/acs.orglett.7b00793
Bredereck's Synthesis Part 2: doi.org/10.1002/cber.19681010108
(I couldn’t find one directly for the chloride, but the Eeros article implies it)
Bredereck's Eeros: doi.org/10.1002/9780470842898.rb350.pub2
N-hydroxymethylphthalimide Synthesis: doi.org/10.1002/chem.201102366
EAS of N-hydroxymethylphthalimide doi.org/10.1055/s-1993-26001
Hey you read this - that means you are now obligated to have a great day!
