Sodium Dithionite Reduction Mechanism | Organic Chemistry @OrganicMechanismsChannel

Uploaded September 2021 | Updated September 2026, 2 weeks ago

The mechanism for the reduction of a substituted pyridine with sodium dithionite. This reaction involves the initial formation of a sodium sulfinate intermediate. This initial intermediate is stable under basic conditions and has the potential to be isolated under such conditions. However, in acidic or neutral conditions, this intermediate decomposes and proceeds towards the final product as shown.

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