Uploaded August 2026 | Updated September 2026, 2 weeks ago
Big changes lie ahead for the world of data processing in many areas: hardware structure, data management, processing algorithms, and even computing types (analog vs. digital.) How must the technical community prepare for these changes? Join noted analyst Jim Handy and IEEE President Tom Coughlin as they look at future computing systems in which storage will appear in new and interesting places. This session will examine how CXL might make persistent memory more widely available and bring processing closer to memory, while AI will drive both the broad adoption of new types of volatile DRAM in HBM stacks as well as the use of emerging nonvolatile technologies in AI-specific “Processing in Memory” (PIM) chips and embedded products for consumer and industrial applications. We’ll also show why computing is poised to convert to persistent caches, and eventually persistent register sets, either as memory on the processor chip or as chiplets, even though the DRAM that lies between persistent storage and persistent caches will remain volatile. We’ll touch on the evolution of “AI Everywhere” and show how altogether different approaches will be used for various applications, from neural networks at the edge and computational storage close to the source of the data, to massive centralized data centers that boast tens of thousands of GPUs, all the while explaining what architectures, software, and new algorithms will be needed to support this shift. These changes will require the development of new approaches to computing that will disrupt the fundamental direction of computing architecture.
Learning Objectives
Discover how persistence will find its way into new levels of the memory/storage hierarchy
Understand the challenges presented by mixed persistent and volatile memory levels
See how emerging memory technologies will create new AI platform architectures
Presented By: Jim Handy, Objective Analysis; Tom Coughlin, Coughlin Associates
Learn More:
SNIA Website: snia.org
SNIA Educational Library: snia.org/library
X/Twitter: twitter.com/SNIA
LinkedIn: linkedin.com/company/snia
Big changes lie ahead for the world of data processing in many areas: hardware structure, data management, processing algorithms, and even computing types (analog vs. digital.) How must the technical community prepare for these changes? Join noted analyst Jim Handy and IEEE President Tom Coughlin as they look at future computing systems in which storage will appear in new and interesting places. This session will examine how CXL might make persistent memory more widely available and bring processing closer to memory, while AI will drive both the broad adoption of new types of volatile DRAM in HBM stacks as well as the use of emerging nonvolatile technologies in AI-specific “Processing in Memory” (PIM) chips and embedded products for consumer and industrial applications. We’ll also show why computing is poised to convert to persistent caches, and eventually persistent register sets, either as memory on the processor chip or as chiplets, even though the DRAM that lies between persistent storage and persistent caches will remain volatile. We’ll touch on the evolution of “AI Everywhere” and show how altogether different approaches will be used for various applications, from neural networks at the edge and computational storage close to the source of the data, to massive centralized data centers that boast tens of thousands of GPUs, all the while explaining what architectures, software, and new algorithms will be needed to support this shift. These changes will require the development of new approaches to computing that will disrupt the fundamental direction of computing architecture.
Learning Objectives
Discover how persistence will find its way into new levels of the memory/storage hierarchy
Understand the challenges presented by mixed persistent and volatile memory levels
See how emerging memory technologies will create new AI platform architectures
Presented By: Jim Handy, Objective Analysis; Tom Coughlin, Coughlin Associates
Learn More:
SNIA Website: snia.org
SNIA Educational Library: snia.org/library
X/Twitter: twitter.com/SNIA
LinkedIn: linkedin.com/company/snia





![DNA MGC+ A Codec for Reliable and Efficient DNA Data Storage
Efficient and reliable data retrieval remains a major challenge in DNA data storage due to the inherent noisiness of the underlying biochemical processes, which lead to both base-level errors and sequence-level dropouts. Here we introduce DNA-MGC+, a novel DNA storage codec designed to enable reliable and efficient data retrieval in the presence of insertion, deletion, and substitution (IDS) errors as well as dropouts. DNA-MGC+ combines an inner coding layer based on the Marker Guess & Check Plus (MGC+) code [1] for correcting IDS errors with an outer Reed-Solomon code that recovers from sequence dropouts and corrects residual inner decoding errors. Our results show that DNA-MGC+ consistently outperforms other codecs across diverse operating conditions. In particular, we observe gains in sequencing depth requirements and decoding time under both Illumina and Nanopore sequencing. We evaluated the performance of DNA-MGC+ in comparison with representative codecs through an in vitro experiment in which sequences encoded using multiple codec configurations were combined in a single oligonucleotide pool. Specifically, a 24-KB compressed file was encoded into oligonucleotides of length 170 bases using two configurations of DNA-MGC+ with different redundancy allocations, design A (1.03 bits/nt) and design B (0.71 bits/nt), as well as two existing codecs: DNA-Aeon [2] (1 bit/nt) and HEDGES [3] (0.61 bits/nt). The oligonucleotide pool was ordered from GenScript (electrochemical synthesis) and sequenced using both Illumina and Oxford Nanopore platforms, with multiple basecalling algorithms evaluated for the Nanopore data. Across all sequencing and basecalling setups, the stored file was recovered with an exact match, albeit with quantitatively different performance outcomes. The results shown in the attached figure indicate that DNA-MGC+ consistently outperforms both DNA-Aeon and HEDGES in terms of the minimum sequencing depth required for reliable decoding, achieving depths below 3x for both Illumina and Nanopore sequencing.
Presented by
Serge Kas Hanna, CNRS
This is a presentation from the 2026 Storage and Computing with DNA Conference.
· Learn More about the SNIA DNA Data Storage Alliance: https://www.snia.org/groups/snia-dna-technology-affiliate
· SNIA Educational Library: https://snia.org/library
· X: https://twitter.com/SNIA
· LinkedIn: https://linkedin.com/company/snia/ DNA MGC+ A Codec for Reliable and Efficient DNA Data Storage](https://i.ytimg.com/vi/gqRbmqRlTMM/mqdefault.jpg)



![Nanocluster positioning on DNA nanostructures for robust information storage
Within the NEO consortium (neodna.eu), we are developing a DNA digital data storage approach based on the precise positioning of objects on DNA origami nanostructures. Compared with sequence-based DNA data storage techniques, the approach aims to achieve higher robustness and faster data reading using atomic force microscopy. On the other hand, the method su6ers from high writing error probabilities and much lower data densities in comparison to the sequence-based methods. A practical example is the placement of streptavidin protein molecules for AFM imaging, where the writing success probabilities hardly reach 80%, and the e6ective “bit” densities are in the order of tens of nanometers. [Rabbe L. RSC Adv., 2025,15, 24536] In the present work, we improve the labelling yield by replacing the streptavidin with metal nanoclusters directly incorporating single-stranded DNA oligomers. Metal nanoclusters can be positioned on the dimensions of nanometers, while still being suitable for AFM imaging. We observe much lower writing error rates in comparison to biotin-streptavidin binding, indicating that our mechanism is less sterically hindered. In this particular case, information writing and deletion are demonstrated using the strand displacement reactions to selectively bind or remove the nanoclusters on DNA origami. Finally, we also demonstrate fast data reading using transmission electron microscopy. The work was supported by the EIC Pathfinder Challenges project 101115317 “NEO”.
Presented by
Jaroslav Kocisek, University of Washington
This is a presentation from the 2026 Storage and Computing with DNA Conference.
· Learn More about the SNIA DNA Data Storage Alliance: https://www.snia.org/groups/snia-dna-technology-affiliate
· SNIA Educational Library: https://snia.org/library
· X: https://twitter.com/SNIA
· LinkedIn: https://linkedin.com/company/snia/ Nanocluster positioning on DNA nanostructures for robust information storage](https://i.ytimg.com/vi/i3O2OX1LRnc/mqdefault.jpg)
