Return of Alpha Gal | Radiolab Podcast @Radiolabpod
Return of Alpha Gal | Radiolab Podcast  @Radiolabpod
Uploaded August 2026 | Updated September 2026, 2 weeks ago
From the Radiolab podcast: Tuck your napkin under your chin. We’re about to serve up a tale of love, loss, and lamb chops—with a side of genetic modification.

Several years ago, in 2016, we told a story about Amy Pearl. For as long as she could remember, Amy loved meat in all its glorious cuts and marbled flavors. And then one day, for seemingly no reason, her body wouldn’t tolerate it. No steaks. No brisket. No weenies. It made no sense: why couldn’t she eat something that she had routinely enjoyed for decades?

It turned out Amy was not alone. And the answer to her mysterious allergy involved maps, a dancing lone star tick, and a very particular sugar called Alpha Gal.

In this update, we discover that our troubles with Alpha Gal go way beyond food. We go to NYU Langone Health hospital to see the second ever transplant of a kidney from a pig into a human, talk to some people at Revivicor, the company that bred the pig in question, and go back to Amy to find out what she thinks about this brave new world.

The original episode was reported by Latif Nasser and produced by Annie McEwen and Matt Kielty. Sound design and scoring from Dylan Keefe, Annie McEwen, and Matt Kielty. Mixed by Dylan Keefe with Arianne Wack.

The update was reported and produced by Sarah Qari. It was sound designed, scored and mixed by Jeremy Bloom.

Learn more about how ticks cause a red meat allergy here: youtube.com/watch?v=GLaTXctxcUA

Episode Segments:
0:00 Chapter 1
19:07 Break 1
19:11 Chapter 2
32:25 Break 2
32:30 Chapter 3
54:20 Credits
55:45 Support

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Photo illustration by Chloe Sun
Video by Joanna Strogatz
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