Uploaded June 2024 | Updated September 2026, 2 weeks ago
Pancreatic Cancer Vaccines With Amazing Results in Phase I
Pancreatic ductal adenocarcinoma is one of the most lethal cancers with a 5 year survival rate of less than 10%. mRNA designer/personalized vaccines are changing this situation. Let's review the results of phase I trials.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Tuesday, Jun. 4 2024 11:37 AM
Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches | Radiation Oncology | Full Text
ro-journal.biomedcentral.com/articles/10.1186/s13014-019-1345-6
NHS England Thousands of NHS patients to access trials of personalised cancer ‘vaccines’
england.nhs.uk/2024/05/thousands-of-nhs-patients-to-access-trials-of-personalised-cancer-vaccines
Three-year Phase 1 Follow-Up Data for mRNA-based Individualized Immunotherapy Candidate Show Persistence of Immune Response and Delayed Tumor Recurrence in Some Patients with Resected Pancreatic Cancer | BioNTech
investors.biontech.de/news-releases/news-release-details/three-year-phase-1-follow-data-mrna-based-individualized
Investigational mRNA Vaccine Induced Persistent Immune Response in Phase 1 Trial of Patients With Pancreatic Cancer | Memorial Sloan Kettering Cancer Center
mskcc.org/news/can-mrna-vaccines-fight-pancreatic-cancer-msk-clinical-researchers-are-trying-find-out
Trial Design
biontech.com/int/en/home/pipeline-and-products/clinical-trials-new/trial-design.html
Cancer vaccines are having a renaissance | MIT Technology Review
technologyreview.com/2024/05/03/1092026/cancer-vaccines-are-having-a-renaissance
NHS England launches scheme to boost signups for personalised cancer vaccine trials | The BMJ
bmj.com/content/385/bmj.q1212#:~:text=The%20vaccines%20currently%20being%20trialled,identify%20and%20destroy%20cancer%20cells.
Pancreatic Cancer Vaccines With Amazing Results in Phase I
Pancreatic ductal adenocarcinoma is one of the most lethal cancers with a 5 year survival rate of less than 10%. mRNA designer/personalized vaccines are changing this situation. Let's review the results of phase I trials.
Want to get access to DrBeen at low price of $4.99/month? Click here: drbeen.com/med-nerd
Want to support this work?:
Buy me a coffee :-) buymeacoffee.com/DrMobeenSyed
Become my patron: patreon.com/mobeensyed?fan_landing=true
PayPal: paypal.me/mobeensyed?locale.x=en_US
My substack: mobeensyedmd.substack.com
#drbeen #koolbeens #HealthPolicy
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Tuesday, Jun. 4 2024 11:37 AM
Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches | Radiation Oncology | Full Text
ro-journal.biomedcentral.com/articles/10.1186/s13014-019-1345-6
NHS England Thousands of NHS patients to access trials of personalised cancer ‘vaccines’
england.nhs.uk/2024/05/thousands-of-nhs-patients-to-access-trials-of-personalised-cancer-vaccines
Three-year Phase 1 Follow-Up Data for mRNA-based Individualized Immunotherapy Candidate Show Persistence of Immune Response and Delayed Tumor Recurrence in Some Patients with Resected Pancreatic Cancer | BioNTech
investors.biontech.de/news-releases/news-release-details/three-year-phase-1-follow-data-mrna-based-individualized
Investigational mRNA Vaccine Induced Persistent Immune Response in Phase 1 Trial of Patients With Pancreatic Cancer | Memorial Sloan Kettering Cancer Center
mskcc.org/news/can-mrna-vaccines-fight-pancreatic-cancer-msk-clinical-researchers-are-trying-find-out
Trial Design
biontech.com/int/en/home/pipeline-and-products/clinical-trials-new/trial-design.html
Cancer vaccines are having a renaissance | MIT Technology Review
technologyreview.com/2024/05/03/1092026/cancer-vaccines-are-having-a-renaissance
NHS England launches scheme to boost signups for personalised cancer vaccine trials | The BMJ
bmj.com/content/385/bmj.q1212#:~:text=The%20vaccines%20currently%20being%20trialled,identify%20and%20destroy%20cancer%20cells.

![Apolipoprotein B (ApoB) and Cardiovascular Disease
What is ApoB?
ApoB is a protein that forms the structural component of apolipoprotein particles. ApoB is now a days being researched as an important atherogenic protein and also possibly a protein that can help identify the risk of cardiac events and strokes with better precision than LDL and cholesterol numbers. Lets understand ApoB-48 and ApoB-100.
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Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true
PayPal: https://paypal.me/mobeensyed?locale.x=en_US
#drbeen #koolbeens #Depression
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Biochemistry, Apolipoprotein B - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK538139/
APOBEC1 - Wikipedia
https://en.wikipedia.org/wiki/APOBEC1
The microsomal triglyceride transfer protein (MTP) is involved in the... | Download Scientific Diagram
https://www.researchgate.net/figure/The-microsomal-triglyceride-transfer-protein-MTP-is-involved-in-the-assembly-of-the_fig2_13226965
Secondary structure prediction and theoretical model of apoB on LDL. A,... | Download Scientific Diagram
https://www.researchgate.net/figure/Secondary-structure-prediction-and-theoretical-model-of-apoB-on-LDL-A-prediction-of_fig2_7076622
Proteomic studies on apoB‐containing lipoprotein in cardiovascular research: A comprehensive review - Gianazza - 2023 - Mass Spectrometry Reviews - Wiley Online Library
https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/mas.21747
Structure of apolipoprotein B-100 in low density lipoproteins - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S0022227520302674
APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 [Homo sapiens (human)] - Gene - NCBI
https://www.ncbi.nlm.nih.gov/gene/339
Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540246/
Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review. - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369156/#:~:text=Trapping%20of%20apoB%20lipoprotein%20particles,contain%20most%20of%20the%20cholesterol.
Oxidation of Apolipoprotein B-100 in Circulating LDL Is Related to LDL Residence Time | Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.ahajournals.org/doi/full/10.1161/01.atv.20.10.e63
Association between apolipoprotein B EcoRI polymorphisms and coronary heart disease | Wiener klinische Wochenschrift
https://link.springer.com/article/10.1007/s00508-016-1072-z
Apolipoprotein B - Wikipedia
https://en.wikipedia.org/wiki/Apolipoprotein_B
Can we reduce vascular plaque buildup? - Harvard Health
https://www.health.harvard.edu/heart-health/can-we-reduce-vascular-plaque-buildup#:~:text=Plaque%20forms%20when%20cholesterol%20lodges,a%20cap%20over%20the%20area. Apolipoprotein B (ApoB) and Cardiovascular Disease](https://i.ytimg.com/vi/vqwJiSQ-9EU/mqdefault.jpg)








