Uploaded April 2026 | Updated September 2026, 2 weeks ago

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Among patients with atrial fibrillation at high risk for stroke and bleeding, left atrial appendage closure was not noninferior to medical therapy in reducing the risk of stroke, embolism, major bleeding, or death at 3 years.

Read the full CLOSURE-AF trial results and Research Summary at NEJM.org.

#cardiology #afib #nejm