Obesity ML Competition: Lecture 3, Part C - Crunches Overview @broadinstitute
Obesity ML Competition: Lecture 3, Part C - Crunches Overview  @broadinstitute
Uploaded December 2025 | Updated September 2026, 1 week ago
The Eric and Wendy Schmidt Center at the Broad Institute and the Broad Diabetes Initiative are proud to launch our new machine learning challenge: the Obesity Machine Learning Challenge: Tackling Metabolic Diseases. This challenge is developed in partnership with Massachusetts General Hospital, Beth Israel Deaconess Medical Center, and Crunch DAO.

Obesity affects more than 890 million people worldwide and dramatically increases risks of type 2 diabetes, cardiovascular diseases, and certain cancers. You will predict how gene perturbations made using CRISPR/Cas9 influence the fate of adipocytes, the pivotal cells in our body related to obesity. Adipocytes are specialized cells storing our body’s fat that can differentiate into energy-storing or energy-burning cells. Top predictions will be experimentally validated in Broad Institute labs.

This lecture series will give you the necessary biology background, along with technology and data details, to participate in the challenge.

The challenge will run from December 2025 - April 2026.

Learn more and register at broad.io/MLC-2025.


Copyright Broad Institute, 2025. All rights reserved.
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Obesity ML Competition: Lecture 3, Part C - Crunches Overview

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