New SPRQ-Nx chemistry and multiomics applications from PAG 33 @PacificBiosciences
New SPRQ-Nx chemistry and multiomics applications from PAG 33  @PacificBiosciences
Uploaded January 2026 | Updated September 2026, 2 hours ago
Watch this presentation from PAG 33 to explore the 2026 PacBio product roadmap, featuring major chemistry updates and new application workflows.

Global Marketing Manager Jacob Brandenburg details how the upcoming SPRQ-Nx chemistry and SMRT Cell reuse capabilities are designed to lower sequencing costs while maintaining high data quality for plant and animal genomes. The session also introduces the SLiC workflow for chromosome-scale assemblies and expands on multiomics capabilities like Fiber-seq, Kinnex kits for annotation, and high-throughput automation.

*What you’ll learn*
* How the SPRQ-Nx chemistry enables SMRT Cell reuse to reduce genome costs.
* How to utilize the single library chromosome-scale assembly (SLiC) workflow to pool HiFi and CiFi libraries.
* The latest updates for the Vega system, including lower input requirements and native 5hmC calling.
* Workflow options for high-throughput applications, including long-read low-pass sequencing and seqWell LongPlex kits.

*Featured speakers*
* Jacob Brandenburg, Global Marketing Manager | Plant and Animal Sciences (PacBio)

00:00 Introduction
00:42 Revio and Vega systems
01:06 SPRQ-Nx chemistry and SMRT Cell reuse
02:50 SPRQ-Nx biodiversity data
05:07 Vega system updates
05:54 CiFi and SLiC applications
09:54 Fiber-seq and chromatin architecture
11:57 Kinnex and isoform discovery
14:04 Long-read low-pass sequencing
16:03 High-throughput automation

*Resources*
pacb.com/datasets
pacb.com/technology/hifi-sequencing

Which new application in the 2026 roadmap will impact your research the most? *Comment below.*

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#PAG33 #Genomics #HiFiSequencing
New SPRQ-Nx chemistry and multiomics applications from PAG 33Long-read sequencing technologies for the generation of reference-level genome assemblies at scaleCiFi Sequencing with Scott Geib (USDA-ARS). PAG 2025 PacBio Workshop Part 6.Changing the game with Revio – Prof Anna LindstrandHiFi informatics for uncovering germline variationCancer sequencing by binding rivals error-corrected SBS for accurate detection of minor populationsIncreasing the throughput of full-length 16S and RNA-Seq with Kinnex™ kitsAmpli-Fi: unlocking HiFi sequencing for low-input and challenging samplesMore samples, lower costs, less time: New PacBio HiFi prep kits + Microbial WGSPacBio Seq it Forward 5K + Fun Run HighlightsIso-Seq Social Club, Vol.  3 - SQANTI3 for isoform classification, annotation and curationHiFi long-read sequencing in All of Us: structural variants in disease
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New SPRQ-Nx chemistry and multiomics applications from PAG 33

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