Uploaded March 2025 | Updated September 2026, 2 weeks ago
Adults under age 50 are part of a large wave of cases of colorectal cancer, which is on track to becoming the leading cause of cancer deaths for this age group by 2030.
A full explanation for the increased incidence eludes experts, but a Westernized diet appears to be an influential factor," says Dr. Rachel Issaka, a UW Medicine digestive system specialist and an associate professor of medicine, Division of Gastroenterology, at the University of Washington School of Medicine.
"Over the past three decades, colorectal cancer cases have doubled in people under age 50,” said Issaka, who also directs the Fred Hutch/UW Medicine Population Health Colorectal Cancer Screening Program.
“While the reasons are not entirely clear,” she said, getting screened, increasing physical activity, maintaining a healthy, balanced diet, avoiding tobacco, and limiting alcohol intake are steps we can all take to reduce our risk of colorectal cancer.”
To bring attention to the importance of early diagnosis, Fred Hutch Cancer Center will host a colorectal cancer screening day Friday, March 21. Multiple first-time colonoscopies will be conducted simultaneously in three procedure suites set aside for this purpose, according to Dr. David Hockenbery, a UW Medicine gastroenterologist and Fred Hutch Cancer Center researcher.
Early detection is key, Hockenbery stressed, with recommended colon cancer screenings beginning at age 45, and even earlier for those with a family history of colorectal cancer or colon polyps.
Download ready to download media for your newscast: docs.google.com/document/d/15DcLgTFfH72xPaFwkJI2PRsij1Dawl82/edit?usp=sharing&ouid=102458169604367614841&rtpof=true&sd=true
UW Medicine Newsroom videos may be embedded on a website or aired in their entirety. If you wish to republish only portions of a video, please contact us because the snippet might include still-image and multimedia files from Getty Images — which cannot be reused for broadcast outside of their existing format. Contact mediarelations@uw.edu to confirm that the video segments you want to republish are approved for that use.
Adults under age 50 are part of a large wave of cases of colorectal cancer, which is on track to becoming the leading cause of cancer deaths for this age group by 2030.
A full explanation for the increased incidence eludes experts, but a Westernized diet appears to be an influential factor," says Dr. Rachel Issaka, a UW Medicine digestive system specialist and an associate professor of medicine, Division of Gastroenterology, at the University of Washington School of Medicine.
"Over the past three decades, colorectal cancer cases have doubled in people under age 50,” said Issaka, who also directs the Fred Hutch/UW Medicine Population Health Colorectal Cancer Screening Program.
“While the reasons are not entirely clear,” she said, getting screened, increasing physical activity, maintaining a healthy, balanced diet, avoiding tobacco, and limiting alcohol intake are steps we can all take to reduce our risk of colorectal cancer.”
To bring attention to the importance of early diagnosis, Fred Hutch Cancer Center will host a colorectal cancer screening day Friday, March 21. Multiple first-time colonoscopies will be conducted simultaneously in three procedure suites set aside for this purpose, according to Dr. David Hockenbery, a UW Medicine gastroenterologist and Fred Hutch Cancer Center researcher.
Early detection is key, Hockenbery stressed, with recommended colon cancer screenings beginning at age 45, and even earlier for those with a family history of colorectal cancer or colon polyps.
Download ready to download media for your newscast: docs.google.com/document/d/15DcLgTFfH72xPaFwkJI2PRsij1Dawl82/edit?usp=sharing&ouid=102458169604367614841&rtpof=true&sd=true
UW Medicine Newsroom videos may be embedded on a website or aired in their entirety. If you wish to republish only portions of a video, please contact us because the snippet might include still-image and multimedia files from Getty Images — which cannot be reused for broadcast outside of their existing format. Contact mediarelations@uw.edu to confirm that the video segments you want to republish are approved for that use.


![This Blood Test May Detect Alzheimer’s Decades Before Symptoms | Research Improves Lives
Alzheimers is usually diagnosed after memory problems start. By then, the damage in the brain has been building for a decade or more.
Dr. Valerie Daggett is a professor of bioengineering at the University of Washington. Her lab studies proteins — how they fold, and what happens when they dont. Along the way they found a protein structure nobody had discovered before. They called it “alpha sheet.”
Her labs research suggests the formation of alpha sheet may be among the earliest molecular events in Alzheimers disease — a trigger for the disease. Based on that work, her team developed a blood test designed to detect these proteins early. Theyre also working on compounds intended to neutralize them.
[CHAPTERS]
0:00 Intro
0:14 What most people think Alzheimers is
0:31 Whats actually happening first
0:49 Alpha sheet, explained
1:26 Looking for the trigger in blood
2:23 Whats driving the pace
2:51 Beyond Alzheimers
3:09 Why this work happens here
Watch the rest of the series:
https://youtube.com/playlist?list=PLpA1iYYE-lh2tY4ddDzIMGEAe3rKFipI3&si=4b_iZWCPZsibhR9N
Learn more about Dr. Daggetts work: https://bioe.uw.edu/portfolio-items/daggett/
Learn more about the people and discoveries behind the science: https://uwmedicine.org/about/research-improves-lives
#Alzheimers #Neuroscience #ResearchImprovesLives This Blood Test May Detect Alzheimer’s Decades Before Symptoms | Research Improves Lives](https://i.ytimg.com/vi/us8SreDtClI/mqdefault.jpg)







