Neuroblastoma: A master of disguise and a challenge to cure @INSIGHTSPublicLecturesNCL
Neuroblastoma: A master of disguise and a challenge to cure  @INSIGHTSPublicLecturesNCL
Uploaded February 2022 | Updated September 2026, 1 week ago
Professor Deborah Tweddle, Newcastle University

Hosted by Professor Sally Shortall, Co-Chair of the Public Lectures Committee

Neuroblastoma is a cancer of the sympathetic nervous system. It is the commonest childhood cancer after brain tumours and one of the most difficult to cure. This lecture will discuss how neuroblastoma presents, and how advances in understanding genetics of this enigmatic cancer over the last 20 years have led to improvements in treatment and cure rates. It will also examine some remaining hurdles and how these might be overcome in the future.

Biography
Professor Deborah Tweddle is an Honorary Consultant in Paediatric and Adolescent Oncology at the Great North Children’s Hospital (GNCH) and Professor of Paediatric Oncology at the Newcastle University Centre for Cancer. Professor Tweddle has a specific interest in childhood neuroblastoma research – biological, translational and clinical – which she has specialised in for over 20 years. As a clinical academic in paediatric oncology, Professor Tweddle spends half of her time at Newcastle University supervising her research team or undertaking duties related to the Children’s Cancer and Leukaemia group tissue bank, of which she is the Scientific Director. The remainder of her time is spent looking after patients with neuroblastoma at the GNCH and co-directing the National Neuroblastoma Genetics Reference centre service with her NHS cytogenetics colleagues.

Live Q&A:
The lecture will be followed by a live Q&A with the speakers. You can submit a question during the event using YouTube Live Chat, via Twitter @InsightsNCL or by sending an email to public.lectures@ncl.ac.uk.

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Neuroblastoma: A master of disguise and a challenge to cure

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