Uploaded April 2024 | Updated September 2026, 2 weeks ago
Darren Zhu, Synthetic Biologist, Technologist, and Filmmaker
The recent proliferation of computational tools and generative models have profound consequences for scientific discovery and creativity, particularly as they can operate at levels of scale and opacity beyond human comprehension. How do we grapple with this potential epistemic and aesthetic upheaval?
This talk explores this question by drawing parallels between metascience and foundation models, origins of life and open-ended evolutions, economic calculation problems and adaptive markets, and synthetic personae and interactive media. Through a mix of synthetic biology, game engines, generative AI models, and 3D printed hardware, my work plays at this boundary of natural versus artificial, scientific versus speculative.
Learn more, follow us on social media and check out our podcasts:
https://linktr.ee/sfiscience
Darren Zhu, Synthetic Biologist, Technologist, and Filmmaker
The recent proliferation of computational tools and generative models have profound consequences for scientific discovery and creativity, particularly as they can operate at levels of scale and opacity beyond human comprehension. How do we grapple with this potential epistemic and aesthetic upheaval?
This talk explores this question by drawing parallels between metascience and foundation models, origins of life and open-ended evolutions, economic calculation problems and adaptive markets, and synthetic personae and interactive media. Through a mix of synthetic biology, game engines, generative AI models, and 3D printed hardware, my work plays at this boundary of natural versus artificial, scientific versus speculative.
Learn more, follow us on social media and check out our podcasts:
https://linktr.ee/sfiscience




![Exploring Chemical Space with Chemputation and Assembly Theory
Lee Cronin, University of Glasgow, SFI
Recent advancements in automation and digitization of chemistry have opened new avenues for exploring chemical complexity. In this talk I will explain how Assembly Theory[1-2] and Chemputation[3-4] can be used to develop a new paradigm to understand and harness the principles of Assembly Theory in chemical synthesis. Assembly Theory provides a framework for quantifying molecular complexity and understanding the emergence of complex chemical systems. Chemputation, on the other hand, offers a standardized method for digitizing and automating chemical synthesis through modular robotic platforms and a chemical programming language (χDL). By combining these approaches, researchers can systematically explore vast chemical spaces, optimize reaction conditions, and potentially discover novel molecules and materials. The integration of these two methodologies enables a new approach to explore chemical space with autonomous experimentation and discovery. As these technologies continue to evolve, they promise to accelerate chemical research, improve reproducibility, provide new insights into the fundamental nature of chemical complexity.
Learn more, follow us on social media and check out our podcasts:
https://linktr.ee/sfiscience Exploring Chemical Space with Chemputation and Assembly Theory](https://i.ytimg.com/vi/hjacdY50gbY/mqdefault.jpg)





