Uploaded July 2023 | Updated September 2026, 2 weeks ago
Tyler Marghetis, University of California, Merced
Our minds can become fixated but they can also undergo sudden, radical change. Think of religious conversions, mathematical insights, artistic breakthroughs. On the surface, such transformations can seem quite different. But might they share deep, underlying properties? Common mechanisms that span timescales? Can we predict when sudden mental transformation is on the horizon? This talk will explore these ruts and ruptures of the human mind. I ll first show that radical transformation isn t limited to the exceptional few but is ubiquitous, occurring reliably in religious belief, scientific understanding, mental health, aesthetic preferences, and more. I ll then describe empirical analyses and formal modeling of two case studies of sudden rupture: professional jazz improvisation and expert mathematical reasoning. I ll end by discussing prospects for a domain-general, multiscale theory of the ruts and ruptures of human thought, from moment-to-moment creativity to decade-long paradigm shifts.
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Tyler Marghetis, University of California, Merced
Our minds can become fixated but they can also undergo sudden, radical change. Think of religious conversions, mathematical insights, artistic breakthroughs. On the surface, such transformations can seem quite different. But might they share deep, underlying properties? Common mechanisms that span timescales? Can we predict when sudden mental transformation is on the horizon? This talk will explore these ruts and ruptures of the human mind. I ll first show that radical transformation isn t limited to the exceptional few but is ubiquitous, occurring reliably in religious belief, scientific understanding, mental health, aesthetic preferences, and more. I ll then describe empirical analyses and formal modeling of two case studies of sudden rupture: professional jazz improvisation and expert mathematical reasoning. I ll end by discussing prospects for a domain-general, multiscale theory of the ruts and ruptures of human thought, from moment-to-moment creativity to decade-long paradigm shifts.
Learn more at https://santafe.edu
Follow us on social media:
twitter.com/sfiscience
instagram.com/sfiscience
facebook.com/santafeinstitute
facebook.com/groups/santafeinstitute
linkedin.com/company/santafeinstitute
Subscribe to SFI's official podcasts:
complexity.simplecast.com
aliencrashsite.org

![Exploring Chemical Space with Chemputation and Assembly Theory
Lee Cronin, University of Glasgow, SFI
Recent advancements in automation and digitization of chemistry have opened new avenues for exploring chemical complexity. In this talk I will explain how Assembly Theory[1-2] and Chemputation[3-4] can be used to develop a new paradigm to understand and harness the principles of Assembly Theory in chemical synthesis. Assembly Theory provides a framework for quantifying molecular complexity and understanding the emergence of complex chemical systems. Chemputation, on the other hand, offers a standardized method for digitizing and automating chemical synthesis through modular robotic platforms and a chemical programming language (χDL). By combining these approaches, researchers can systematically explore vast chemical spaces, optimize reaction conditions, and potentially discover novel molecules and materials. The integration of these two methodologies enables a new approach to explore chemical space with autonomous experimentation and discovery. As these technologies continue to evolve, they promise to accelerate chemical research, improve reproducibility, provide new insights into the fundamental nature of chemical complexity.
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https://linktr.ee/sfiscience Exploring Chemical Space with Chemputation and Assembly Theory](https://i.ytimg.com/vi/hjacdY50gbY/mqdefault.jpg)








