Uploaded March 2026 | Updated September 2026, 3 minutes ago
Our understanding of memory—and how it falters—is being reshaped by breakthroughs at MIT’s Picower Institute for Learning and Memory and Aging Brain Initiative. Researchers there are uncovering how brain-wide networks, molecular pathways, and rhythmic electrical activity come together to sustain cognition—and how their disruption drives diseases like Alzheimer’s. In this session, Picower Professor Li-Huei Tsai will explore how systems-level studies of neuronal circuits are revealing new insights into disease progression, and how restoring healthy communication between brain regions may help protect memory. By connecting fundamental neuroscience to potential new therapies, this work offers fresh hope for understanding—and ultimately slowing—the effects of neurodegeneration.
-Discover how the Picower Institute’s research on fats is reshaping our understanding of brain health and Alzheimer’s risk: https://picower.mit.edu/news/focus-fats
-Explore how 40Hz sensory stimulation could offer measurable benefits for some Alzheimer’s patients: https://news.mit.edu/2025/study-suggests-40hz-sensory-stimulation-may-benefit-some-alzheimers-patients-1114
-See how a groundbreaking human brain model is accelerating disease research and drug discovery: https://news.mit.edu/2025/researchers-invent-human-brain-model-to-enable-disease-research-drug-discovery-1105
-Learn how the APOE4 risk gene disrupts cholesterol management and compromises neural insulation: https://news.mit.edu/2022/alzheimers-risk-gene-undermines-insulation-of-brain-wiring-1122
-Find out how 40Hz vibration therapy reduced Alzheimer’s pathology and symptoms in preclinical studies: https://news.mit.edu/2023/40-hz-vibrations-reduce-alzheimers-pathology-symptoms-mouse-models-0605
Support from the MIT alumni and friends makes it possible for scientists to explore solutions or restoring aging brain health. Please consider making an optional gift to the Aging Brain Initiative Fund, as your generosity directly advances this vital research: https://giving.mit.edu/form?fundId=3895642&source=WBFPE
Register now to watch the next MIT Alumni Forum on April 9, when A. John Hart SM ’02, PhD ’06, Class of 1922 Professor and head of the Department of Mechanical Engineering at MIT, will discuss digital tools and humans shaping manufacturing’s future: https://alumic.mit.edu/s/1314/17form/interior.aspx?sid=1314&gid=13&pgid=66932&content_id=74275
Our understanding of memory—and how it falters—is being reshaped by breakthroughs at MIT’s Picower Institute for Learning and Memory and Aging Brain Initiative. Researchers there are uncovering how brain-wide networks, molecular pathways, and rhythmic electrical activity come together to sustain cognition—and how their disruption drives diseases like Alzheimer’s. In this session, Picower Professor Li-Huei Tsai will explore how systems-level studies of neuronal circuits are revealing new insights into disease progression, and how restoring healthy communication between brain regions may help protect memory. By connecting fundamental neuroscience to potential new therapies, this work offers fresh hope for understanding—and ultimately slowing—the effects of neurodegeneration.
-Discover how the Picower Institute’s research on fats is reshaping our understanding of brain health and Alzheimer’s risk: https://picower.mit.edu/news/focus-fats
-Explore how 40Hz sensory stimulation could offer measurable benefits for some Alzheimer’s patients: https://news.mit.edu/2025/study-suggests-40hz-sensory-stimulation-may-benefit-some-alzheimers-patients-1114
-See how a groundbreaking human brain model is accelerating disease research and drug discovery: https://news.mit.edu/2025/researchers-invent-human-brain-model-to-enable-disease-research-drug-discovery-1105
-Learn how the APOE4 risk gene disrupts cholesterol management and compromises neural insulation: https://news.mit.edu/2022/alzheimers-risk-gene-undermines-insulation-of-brain-wiring-1122
-Find out how 40Hz vibration therapy reduced Alzheimer’s pathology and symptoms in preclinical studies: https://news.mit.edu/2023/40-hz-vibrations-reduce-alzheimers-pathology-symptoms-mouse-models-0605
Support from the MIT alumni and friends makes it possible for scientists to explore solutions or restoring aging brain health. Please consider making an optional gift to the Aging Brain Initiative Fund, as your generosity directly advances this vital research: https://giving.mit.edu/form?fundId=3895642&source=WBFPE
Register now to watch the next MIT Alumni Forum on April 9, when A. John Hart SM ’02, PhD ’06, Class of 1922 Professor and head of the Department of Mechanical Engineering at MIT, will discuss digital tools and humans shaping manufacturing’s future: https://alumic.mit.edu/s/1314/17form/interior.aspx?sid=1314&gid=13&pgid=66932&content_id=74275
![MIT Holiday Greeting 2023 - with Audio Description [AD]](https://i.ytimg.com/vi/GlIF6y2DNNI/mqdefault.jpg "MIT Holiday Greeting 2023 - with Audio Description [AD]
Happy Holidays from MIT President Sally Kornbluth and Professor Danny Lew!
View the video without audio description: https://youtu.be/hXrTLWMhbHQ
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2023 MIT Holiday Greeting team
Creative director: Emily Muldoon Kathan
Core team: Brielle Domings, Brian Geer
Animation: kerpy
Email and digital production: Russell Boulais, Greg Bourne, Gina DAllesandro, Emily Dufresne, Julie Fox, Karla Casey, Kimberly Mancino, Kathryn ONeill, Kate Repantis, Steve Thomas, Margaret Wong, and Mikko Zager
And MIT Alumni Association Chief Executive Officer Whitney T. Espich
#audiodescription")
![[AD] YouTuber Finds Niche as College Admissions Mentor](https://i.ytimg.com/vi/IkB0uZ2eEUo/mqdefault.jpg "[AD] YouTuber Finds Niche as College Admissions Mentor
View without audio description: https://youtu.be/p867fsY8ebk
Read more about Gohar Khan 21 on Slice of MIT: https://bit.ly/3QjnnaR
As a first-generation student from a small town, Gohar Khan ’21 had to navigate the college admissions process largely on his own, scouring the internet to figure out what admissions officers might expect from essays and interviews. He founded his YouTube channel, @goharsguide , to make the process easier for other young people.
Code: KICDSDV8D0O1IPJ5")
