Dr Alexander Wunsch: Ultraviolet Light in Human Evolution @maxgulhanemd

Uploaded March 2026 | Updated September 2026, 1 hour ago

We explore how light shaped life from an evolutionary perspective — from the great oxygenation event and mitochondrial endosymbiosis to modern understandings of role of ultraviolet light in health.

Dr. Alexander Wunsch, MD, PhD is a German physician, researcher and one of the world’s leading experts in photobiology and light medicine.

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DISCLAIMER: The content in this podcast is purely for informational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard professional medical advice or delay in seeking it because of something you have heard on this podcast or YouTube channel. Do not make medication changes without first consulting your treating clinician.

#ultravioletlight #solarcallus #sunglasses #mitochondria #greatoxygenationevent

Dr Alexander Wunsch: Ultraviolet Light in Human Evolution

$Dr Jack Kruse: Light, Melanin, POMC in Human Evolution & Disease Dr Jack Kruse joins me in an epic three-hour interview to weave the story of human evolution fundamentally tied to light. He describes our transition from furry ground dwelling mammals to upright walking primates, the critical role of the POMC gene, melanin, the function of mitochondria as producers of endogenous light, as well as creation of the electricity grid and the distortion of the light environment as the key underlying driver of modern chronic disease. Dr Jack Kruse is a neurosurgeon, biophysicist, health optimisation researcher and founding father of the circadian health / mitochondrial medicine movement. This is the first in a series of interviews with Dr Kruse that will also cover water and magnetism, two further installments in a trilogy that strongly challenges the centrality of diet as the chief determinant of optimal health. Stay tuned for further episodes. CONSULT DR MAX 🩺 Comprehensive Health Consulting - www.drmaxgulhane.com/consulting SUPPORT MY WORK 🎤 PRIVATE MEMBERS GROUP on Skool platform - weekly Q&A, my 52-page eBook, PDF resource downloads & more. USD20/month, cancel anytime. https://www.skool.com/dr-maxs-circadian-reset 🚨 DAYLIGHT COMPUTER. Blue-light free computer that doesnt wreck your circadian rhythm. Now shipping around the world. Code DRMAX for $25 off. https://buy.daylightcomputer.com/DRMAX 🚨 VIVA RAYS. Premium blue light blocking glasses with the most useful 3 in 1 clip on frame sets. Code DRMAX for 15% off. https://vivarays.com/dr-maxgulhane 🚨 GEMBA RED. Highest quality photobiomodulation / redlight therapy devices, shipping within the USA. Code DRMAX for 10% off. https://gembared.com TIMESTAMPS 00:00:00 Dr Maxs intro 00:05:11 Dr Kruse’s backstory 00:10:22 Differences between centralized and decentralized medicine 00:12:32 Incongruence in Darwin’s theories of evolution 00:13:27 Evolution of mammals from ground dwelling creatures 00:17:57 The POMC gene and its cleavage products allowed mammals to survive the dinosaur extinction event 00:28:12 POMC, the leptin melanocortin pathway and human metabolism 00:34:37 POMC and autoimmunity 00:38:42 To understand the effect of light on biology, we need to understand physics 00:41:15 UV light from the sun is critical to stimulating POMC 00:46:42 Robert O. Becker’s research on bioelectrics and cellular DC electric current 00:50:22 POMC, melanin and biological semi-conductors 00:59:52 Dr Max’s summary of the first hour 01:05:05 What is leptin and its function? 01:12:28 All mammalian cells generate UV light in the mitochondria and use it to signal 01:19:27 The biological function of melanin 01:26:19 Dr Max’s summary of the function of leptin 01:30:05 Reversing vitiligo, grey hair & melanin loss with sun & UV light 01:36:43 Melanoma develops in absence of full spectrum (red/infrared) sunlight 01:39:38 Dr Max’s summary of the first 1.5 hours 01:41:22 What are mitochondria? 01:47:29 Competing theories on the factors that influenced development of human brain 01:49:27 History of biological semi-conductors and importance of DHA in the SN2 position 01:56:36 Photoreceptors, neuropsin and mental health conditions 02:08:00 Incongruent light signals between eye and skin creates disease 02:12:47 The harms of taking exogenous melatonin 02:17:52 Why blocking UV light causes melanoma 02:24:32 Rebuttals to ‘light causes all diseases’ point of view 02:38:42 Understanding light is critical to understanding the root causes of patients diseases 02:54:03 Dr Kruse’s take on premature male pattern balding and refractory error aka ‘soyjak meme’ 02:59:49 Why we see low serum Vitamin D in overweight or obese people 03:08:02 Three actionable steps for the listener FURTHER READING The Monk Who Sold His Ferrari – Robin Sharma https://www.amazon.com.au/Monk-Who-Sold-His-Ferrari/dp/0062515675 Leptin Rx – https://jackkruse.com/how-does-the-leptin-rx-work/ Cold Thermogenesis Protocol – https://jackkruse.com/the-evolution-of-the-leptin-rx/ POMC - https://en.wikipedia.org/wiki/Proopiomelanocortin CLIP - https://en.wikipedia.org/wiki/Corticotropin-like_intermediate_peptide The Body Electric – Robert O. Becker https://www.amazon.com.au/Body-Electric-Robert-Becker/dp/0688069711 Dr Jack Kruse Patreon Blog Read Quantum Engineering #27-36 Quantum Engineering #27 Why is sunscreen and sunglasses harmful? https://www.patreon.com/posts/quantum-27-why-79154586 Follow DR MAX Website: https://drmaxgulhane.com/ Twitter: https://twitter.com/MaxGulhaneMD Instagram: https://www.instagram.com/dr_max_gulhane/ Apple Podcasts: https://podcasts.apple.com/podcast/id1661751206 Spotify: https://open.spotify.com/show/6edRmG3IFafTYnwQiJjhwR #light #mitochondria #mitochondriac #circadianhealth #sun #sunlight #circadianrhythm$

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