Celebrating 100 years of Discoveries | DNA from Watson, Crick and Franklin to Ramakrishnan @medicalresearchcouncil
Celebrating 100 years of Discoveries | DNA from Watson, Crick and Franklin to Ramakrishnan  @medicalresearchcouncil
Uploaded December 2013 | Updated September 2026, 1 week ago
Exploring the work of James Watson, Francis Crick and Rosalind Franklin (Genetics) through to Venki Ramakrishnan (Molecular Biology), part of the MRC series to celebrate 100 years of life-changing discoveries.

The structure of #DNA was discovered by Crick and Watson based on Franklin and others at King's College London. A great deal of ingenuity went into creating that model of the double helix. However, though the structure suggested how DNA might work. it didn't explain how DNA would contain the information to make proteins, how #genes could be switched on and off, or how they could be regulated.

Doctor Venki Ramakrishnan's current work looks at the structure and function of the ribosome. There are thousands of genes in the human body which contain information on how to make proteins. The process of how to use that information, how to read it and stitch together the proteins is done by the ribosome.

Understanding of the ribosome has already led to significant medical advances, with researchers designing #antibiotics which use molecules that block the ribosomes of bacteria. It has also paved the way for improved antibiotics, such as those with the potential to overcome resistance.

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Celebrating 100 years of Discoveries | DNA from Watson, Crick and Franklin to Ramakrishnan

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