The Proof with Simon Hill | Can We Slow Down Aging? Venki Ramakrishnan on DNA Damage & Protein Synthesis for Extended Healthspan @TheProofWithSimonHill | Uploaded October 2024 | Updated October 2024, 3 hours ago.
Can we turn back the clock on our biology? In Episode #334, I sit down with Nobel Prize-winning structural biologist Dr Venki Ramakrishnan to discuss why we age, how the aging process works, and the cutting-edge scientific advancements that could help us live longer and healthier lives. Dr Ramakrishnan’s work has led to groundbreaking insights into molecular biology, and today, we explore what science tells us about aging, the factors that influence it, and how we might slow it down.
👇 Visit The Proof website for the full show notes and supporting studies. 👇 theproof.com/podcast
Dr Venki Ramakrishnan is a Nobel Prize-winning scientist who shared the 2009 Nobel Prize in Chemistry for his research into the structure of the ribosome. He currently runs his research group at the MRC Laboratory of Molecular Biology in Cambridge, England, and is a member of the National Academy of Sciences. Dr Ramakrishnan served as president of the Royal Society from 2015 to 2020 and is the author of “Gene Machine” and “Why We Die”.
Connect with Dr Venki Ramakrishnan:
- Profile: www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/venki-ramakrishnan
- Gene Machine book: https://www.booktopia.com.au/gene-machine-venki-ramakrishnan/book/9781786076717.html
- Why We Die book: https://www.booktopia.com.au/why-we-die-venki-ramakrishnan/book/9781529369250.html?source=pla&gad_source=1&gclid=Cj0KCQjwpP63BhDYARIsAOQkATYzbEt8NV2xN6PAdnuT7E0VqNxMI0KMTp01QpSyt-y81-oMDwr1sDYaAtsBEALw_wcB
If you have any additional questions you would like answered in the future, let me know in the comments.
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends.
Enjoy, friends.
Simon
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Head to 38tera.com and use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com eimele.com/ and use code SIMON at checkout for 20% off your first order and subscriptions.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon](join.whoop.com/simon
LMNT
Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill theproof.com/podcast
Author of The Proof is in the Plants theproof.com/book
Watch the episodes on YouTube youtube.com/c/TheProofWithSimonHill?sub_confirmation=1 or listen on Apple podcasts.apple.com/au/podcast/the-proof-with-simon-hill/id1367773989 / Spotify open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi?si=84831dc34dc9408b
Connect with me on Instagram instagram.com/theproof/, Twitter mobile.twitter.com/theproof, and Facebook facebook.com/theproofwithsimonhill
Nourish your gut with my Plant-Based Ferments Guide theproof.com/ferments
Download my complimentary Two-Week Meal Plan plantproof.com/mealplan and high protein Plant Performance recipe book theproof.com/performance
Timestamps:
00:00 Introduction to Aging and Longevity Science
00:57 Ribosomes and Their Role in Longevity Research
05:09 Controversies in Anti-Aging Research
11:25 Understanding the Biology of Aging
22:10 Genetics and Evolution: How They Shape Human Lifespan
30:44 Youthful Cells: The Future of Longevity Studies
47:14 Biological Interventions in Aging: Potential and Risks
53:18 Ancestral Living and Traditional Medicine for Longevity
57:56 Cellular Aging Mechanisms: A Deeper Look
01:05:04 Protein Synthesis and Its Impact on Aging Processes
01:17:36 DNA Damage and Repair: Implications for Aging
01:24:54 Lifestyle Choices That Influence Aging and Lifespan
01:33:59 Philosophical Perspectives on Extended Human Longevity
01:44:26 Concluding Thoughts on Aging and Longevity Research
Can we turn back the clock on our biology? In Episode #334, I sit down with Nobel Prize-winning structural biologist Dr Venki Ramakrishnan to discuss why we age, how the aging process works, and the cutting-edge scientific advancements that could help us live longer and healthier lives. Dr Ramakrishnan’s work has led to groundbreaking insights into molecular biology, and today, we explore what science tells us about aging, the factors that influence it, and how we might slow it down.
👇 Visit The Proof website for the full show notes and supporting studies. 👇 theproof.com/podcast
Dr Venki Ramakrishnan is a Nobel Prize-winning scientist who shared the 2009 Nobel Prize in Chemistry for his research into the structure of the ribosome. He currently runs his research group at the MRC Laboratory of Molecular Biology in Cambridge, England, and is a member of the National Academy of Sciences. Dr Ramakrishnan served as president of the Royal Society from 2015 to 2020 and is the author of “Gene Machine” and “Why We Die”.
Connect with Dr Venki Ramakrishnan:
- Profile: www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/venki-ramakrishnan
- Gene Machine book: https://www.booktopia.com.au/gene-machine-venki-ramakrishnan/book/9781786076717.html
- Why We Die book: https://www.booktopia.com.au/why-we-die-venki-ramakrishnan/book/9781529369250.html?source=pla&gad_source=1&gclid=Cj0KCQjwpP63BhDYARIsAOQkATYzbEt8NV2xN6PAdnuT7E0VqNxMI0KMTp01QpSyt-y81-oMDwr1sDYaAtsBEALw_wcB
If you have any additional questions you would like answered in the future, let me know in the comments.
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends.
Enjoy, friends.
Simon
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Head to 38tera.com and use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com eimele.com/ and use code SIMON at checkout for 20% off your first order and subscriptions.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon](join.whoop.com/simon
LMNT
Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill theproof.com/podcast
Author of The Proof is in the Plants theproof.com/book
Watch the episodes on YouTube youtube.com/c/TheProofWithSimonHill?sub_confirmation=1 or listen on Apple podcasts.apple.com/au/podcast/the-proof-with-simon-hill/id1367773989 / Spotify open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi?si=84831dc34dc9408b
Connect with me on Instagram instagram.com/theproof/, Twitter mobile.twitter.com/theproof, and Facebook facebook.com/theproofwithsimonhill
Nourish your gut with my Plant-Based Ferments Guide theproof.com/ferments
Download my complimentary Two-Week Meal Plan plantproof.com/mealplan and high protein Plant Performance recipe book theproof.com/performance
Timestamps:
00:00 Introduction to Aging and Longevity Science
00:57 Ribosomes and Their Role in Longevity Research
05:09 Controversies in Anti-Aging Research
11:25 Understanding the Biology of Aging
22:10 Genetics and Evolution: How They Shape Human Lifespan
30:44 Youthful Cells: The Future of Longevity Studies
47:14 Biological Interventions in Aging: Potential and Risks
53:18 Ancestral Living and Traditional Medicine for Longevity
57:56 Cellular Aging Mechanisms: A Deeper Look
01:05:04 Protein Synthesis and Its Impact on Aging Processes
01:17:36 DNA Damage and Repair: Implications for Aging
01:24:54 Lifestyle Choices That Influence Aging and Lifespan
01:33:59 Philosophical Perspectives on Extended Human Longevity
01:44:26 Concluding Thoughts on Aging and Longevity Research
