Mark Hyman, MD | Can We Learn From Centenarians' DNA? #longevity @drmarkhyman | Uploaded February 2024 | Updated October 2024, 1 day ago.
We are on the leading edge of a revolution that will dramatically change the way we age. Most chronic diseases are united by one primary cause—the biology of aging itself. 

While there are genetic and environmental bases for many age-related diseases (diabetes, heart disease, cancer, dementia, etc.), aging increases our chances of contracting them more than any other factor alone—making aging the primary driver of the global epidemic of chronic disease.

On today’s episode of The Doctor’s Farmacy, I’m excited to talk to Dr. Nir Barzilai about the key factors that contribute to the aging process and the diseases of aging along with the specific genetic markers or pathways that influence lifespan. 

In this episode, we discuss:
- The hallmarks of aging
- What causes the hallmarks of aging?
- Dr. Barzilai’s research on centenarians
- Why living to 100+ years is good for the economy
- What enables someone to live to 100 years old?
- Taking growth hormone and Metformin have different effects based on your age
- The connection between HDL cholesterol and longevity
- Dr. Barzilai’s research on Metformin
- How Metformin works in the body and on muscle growth
- Dr. Barzilai’s personal longevity

You can find it on your favorite podcast platform.