Uploaded November 2023 | Updated September 2026, 1 week ago
The novel biology of CAR-T cells have transformed the treatment of extremely aggressive cancers. In this talk, Julia Carnevale and Justin Eyquem describe how rewiring the biology of immune cells can help improve outcomes for patients with aggressive cancers. They will explore how exciting tools like genomic editing harness the power of CRISPR-based discovery platforms to identify novel gene targets.
Speakers
Julia Carnevale, MD, is an assistant professor in the Division of Hematology and Oncology at UCSF Health and an affiliate investigator at the Gladstone Institutes. She treats patients with gastrointestinal cancers and also performs research into finding novel therapies for these diseases.
Justin Eyquem, PhD, is an assistant professor in the Departments of Medicine and Microbiology and Immunology at UCSF and an affiliate investigator at the Gladstone Institutes. He joined UCSF as a Parker fellow in 2019 and became assistant professor at the Gladstone Institute of Genomic Immunology in 2021.
Note: Closed captions will be available within 48-72 hours after posting.
Program
Lekshmi Santhosh: Introduction
00:02:37-00:24:49 – Justin Eyquem, PhD, assistant professor in the Departments of Medicine and Microbiology and Immunology at UCSF and affiliate investigator at the Gladstone Institutes
00:24:57-00:45:53 – Julia Carnevale, MD, assistant professor in the Division of Hematology and Oncology at UCSF Health and affiliate investigator at the Gladstone Institutes
00:46:26-00:57:26 – Q&A
See previous Medical Grand Rounds:
October 19: Mapping the Clinical and Multi-Omics Terrain to New Horizons in Inflammatory Bowel Disease
youtu.be/zxM_1vL2d4g
October 12: Improving Value in Medicine: Health Technology Assessment and Determining the Value of Treatments
youtube.com/watch?v=ujA--4BtFSU&t=1763s
October 5: A Learning Journey: Understanding and Improving Equity in Palliative Medicine
youtu.be/pmMvWeD-6O4
See all UCSF Covid-19 grand rounds, which have been viewed over 3M times, at youtube.com/playlist?list=PLp2l8GCZXFqSgUfwaResQ7rGwKbGIUi_m.
The novel biology of CAR-T cells have transformed the treatment of extremely aggressive cancers. In this talk, Julia Carnevale and Justin Eyquem describe how rewiring the biology of immune cells can help improve outcomes for patients with aggressive cancers. They will explore how exciting tools like genomic editing harness the power of CRISPR-based discovery platforms to identify novel gene targets.
Speakers
Julia Carnevale, MD, is an assistant professor in the Division of Hematology and Oncology at UCSF Health and an affiliate investigator at the Gladstone Institutes. She treats patients with gastrointestinal cancers and also performs research into finding novel therapies for these diseases.
Justin Eyquem, PhD, is an assistant professor in the Departments of Medicine and Microbiology and Immunology at UCSF and an affiliate investigator at the Gladstone Institutes. He joined UCSF as a Parker fellow in 2019 and became assistant professor at the Gladstone Institute of Genomic Immunology in 2021.
Note: Closed captions will be available within 48-72 hours after posting.
Program
Lekshmi Santhosh: Introduction
00:02:37-00:24:49 – Justin Eyquem, PhD, assistant professor in the Departments of Medicine and Microbiology and Immunology at UCSF and affiliate investigator at the Gladstone Institutes
00:24:57-00:45:53 – Julia Carnevale, MD, assistant professor in the Division of Hematology and Oncology at UCSF Health and affiliate investigator at the Gladstone Institutes
00:46:26-00:57:26 – Q&A
See previous Medical Grand Rounds:
October 19: Mapping the Clinical and Multi-Omics Terrain to New Horizons in Inflammatory Bowel Disease
youtu.be/zxM_1vL2d4g
October 12: Improving Value in Medicine: Health Technology Assessment and Determining the Value of Treatments
youtube.com/watch?v=ujA--4BtFSU&t=1763s
October 5: A Learning Journey: Understanding and Improving Equity in Palliative Medicine
youtu.be/pmMvWeD-6O4
See all UCSF Covid-19 grand rounds, which have been viewed over 3M times, at youtube.com/playlist?list=PLp2l8GCZXFqSgUfwaResQ7rGwKbGIUi_m.
