BioTorsdag: A small peptide that could save the horseshoe crab @realfagsbiblioteket

UiO Realfagsbiblioteket | BioTorsdag: A small peptide that could save the horseshoe crab @realfagsbiblioteket | Uploaded January 2024 | Updated October 2024, 1 hour ago.
Welcome to 2024's first BioTorsdag! This time, Professor Dirk Linke at the Department of Biosciences will unravel the intricate relationship between molecular biology, medicine, and the conservation of biodiversity.

Our research group tries to understand bacterial adhesion.

As part of our work on the molecules that mediate adhesion to host cells and to medical implants, we serendipitously identified a peptide that can bind lipopolysaccharides with extremely high affinity.

Lipopolysaccharides (LPS) act as endotoxins, and are key molecules in causing septic shock - "blood poisoning". Our peptide might be useful in developing sensitive assays for endotoxin detection, and for removing endotoxins from biopharmaceutical production pipelines or even from patient blood.

In this lecture, I will describe how this connects to the horseshoe crab, a living fossil and endangered species.

https://www.ub.uio.no/english/courses-events/events/mednat/ureal/2024/bio-thursday-2024-01-24.html

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