Uploaded August 2020 | Updated September 2026, 2 weeks ago
The first 100 people to go to blinkist.com/scienceasylum are going to get unlimited access for 1 week to try it out. You'll also get 25% off if you want the full membership.
The action potential allows neurons to talk to each other and to other cells in the body. It's a process we can make easier to understand by modeling it as an electric circuit. That's exactly what the Hodgkin-Huxley model does! Let's learn how it works.
Creator/Host/Co-Writer: Nick Lucid
Co-Writer: Keith van Antwerp
Editor/Animator: Nick Lucid
________________________________
VIDEO ANNOTATIONS/CARDS
Why Does Stuff Happen? Gradients!
youtu.be/Kbf6H5dwTFc
You Do NOT "Charge" A Battery!
youtu.be/cPQbkTkGsnI
________________________________
RELATED YOUTUBE VIDEOS
Neuro Transmissions on Neurons:
youtu.be/8TG8QCkKpHI
youtu.be/HzrJWTtw8VM
Amoeba Sisters on Sodium Potassium Pump:
youtu.be/7NY6XdPBhxo
________________________________
SUPPORT THE SCIENCE ASYLUM
Patreon:
patreon.com/ScienceAsylum
Advanced Theoretical Physics (Paperback):
lulu.com/shop/nick-lucid/advanced-theoretical-physics-a-historical-perspective/paperback/product-24250687.html
Advanced Theoretical Physics (eBook):
gumroad.com/l/ubSc
Merchandise:
scienceasylum.com
________________________________
HUGE THANK YOU TO THESE PATRONS
Asylum Counselors:
Matthew O'Connor, Nikolaos Vasiloglou II
Asylum Orderlies:
William Morton, Fabio Manzini
Einsteinium Crazies:
Wacky, Eoin O'Sullivan, Ken Davis, LT Marshall, Ilya Yashin
Plutonium Crazies:
Al Davis, Compuart, Ellis Hall, Kevin MacLean
Platinum Crazies:
André Weyermann, CrouchingTigerHiddenAdam, Eugene Boone, Jon Adams, Jonathan Reel, Kyle Bowles, Marino Hernandez, Mikayla Eckel Cifrese, Mr. Orn Jonasar, Olga Cooperman, Rick Dinning, Stephen Blinn, Vittorio Monaco
________________________________
OTHER SOURCES
https://neuronaldynamics.epfl.ch/online/Ch2.S2.html
britannica.com/biography/Luigi-Galvani
scientificamerican.com/article/why-does-the-brain-need-s
nobelprize.org/prizes/medicine/1906/summary
nobelprize.org/prizes/medicine/1963/summary
________________________________
LINKS TO COMMENTS
youtube.com/watch?v=TxW6_E3uLuo&lc=UgzOGpsQQvxzMJoKu8d4AaABAg
________________________________
IMAGE CREDITS
Storm Video (CC0 License):
pexels.com/video/storm-approaching-857241
Hodgkin and Huxley Portraits:
nobelprize.org/prizes/medicine/1963/summary
Public Domain Illustrations:
commons.wikimedia.org/wiki/File:Akropolis_by_Leo_von_Klenze.jpg
commons.wikimedia.org/wiki/File:Frontispiece_to_Frankenstein_1831.jpg
commons.wikimedia.org/wiki/File:Galvani_frog_legs_experiment_setup.png
commons.wikimedia.org/wiki/File:Galvani-frogs-legs-electricity.jpg
http://jv.gilead.org.il/rpaul/Vingt%20mille%20lieues%20sous%20les%20mers/
Public Domain Portraits:
commons.wikimedia.org/wiki/File:Frans_Hals_-_Portret_van_Ren%C3%A9_Descartes.jpg
commons.wikimedia.org/wiki/File:Luigi_Galvani,_oil-painting.jpg
commons.wikimedia.org/wiki/File:Alessandro_Volta.jpeg
commons.wikimedia.org/wiki/File:Jacques-Louis_David_-_Napoleon_Crossing_the_Alps_-_Kunsthistorisches_Museum.jpg
commons.wikimedia.org/wiki/File:Hans_Christian_%C3%98rsted_daguerreotype.jpg
commons.wikimedia.org/wiki/File:Ampere_Andre_1825.jpg
commons.wikimedia.org/wiki/File:Faraday-Millikan-Gale-1913.jpg
commons.wikimedia.org/wiki/File:Mary_Wollstonecraft_Shelley_Rothwell.tif
commons.wikimedia.org/wiki/File:Cajal-Restored.jpg
Clipart:
openclipart.org
commons.wikimedia.org/wiki/File:Complete_neuron_cell_diagram_en.svg
Laboratory Background:
commons.wikimedia.org/wiki/File:Interior_of_a_laboratory(GN04185).jpg
________________________________
TIME CODES
00:00 Cold Open
00:52 History of Electrophysiology
04:18 What is a Nerve?
06:23 Hodgkin-Huxley Model
10:16 Action Potentials
11:26 Bringing it all together
14:13 Outro
14:30 Sponsor Message
15:55 Featured Comment
________________________________
Corrections:
10:11 Technically, each of the circuit components of the Hodgkin-Huxley circuit do not represent a single component in the cell. It's more accurate to say the circuit components represent a population of the cell components.
The first 100 people to go to blinkist.com/scienceasylum are going to get unlimited access for 1 week to try it out. You'll also get 25% off if you want the full membership.
The action potential allows neurons to talk to each other and to other cells in the body. It's a process we can make easier to understand by modeling it as an electric circuit. That's exactly what the Hodgkin-Huxley model does! Let's learn how it works.
Creator/Host/Co-Writer: Nick Lucid
Co-Writer: Keith van Antwerp
Editor/Animator: Nick Lucid
________________________________
VIDEO ANNOTATIONS/CARDS
Why Does Stuff Happen? Gradients!
youtu.be/Kbf6H5dwTFc
You Do NOT "Charge" A Battery!
youtu.be/cPQbkTkGsnI
________________________________
RELATED YOUTUBE VIDEOS
Neuro Transmissions on Neurons:
youtu.be/8TG8QCkKpHI
youtu.be/HzrJWTtw8VM
Amoeba Sisters on Sodium Potassium Pump:
youtu.be/7NY6XdPBhxo
________________________________
SUPPORT THE SCIENCE ASYLUM
Patreon:
patreon.com/ScienceAsylum
Advanced Theoretical Physics (Paperback):
lulu.com/shop/nick-lucid/advanced-theoretical-physics-a-historical-perspective/paperback/product-24250687.html
Advanced Theoretical Physics (eBook):
gumroad.com/l/ubSc
Merchandise:
scienceasylum.com
________________________________
HUGE THANK YOU TO THESE PATRONS
Asylum Counselors:
Matthew O'Connor, Nikolaos Vasiloglou II
Asylum Orderlies:
William Morton, Fabio Manzini
Einsteinium Crazies:
Wacky, Eoin O'Sullivan, Ken Davis, LT Marshall, Ilya Yashin
Plutonium Crazies:
Al Davis, Compuart, Ellis Hall, Kevin MacLean
Platinum Crazies:
André Weyermann, CrouchingTigerHiddenAdam, Eugene Boone, Jon Adams, Jonathan Reel, Kyle Bowles, Marino Hernandez, Mikayla Eckel Cifrese, Mr. Orn Jonasar, Olga Cooperman, Rick Dinning, Stephen Blinn, Vittorio Monaco
________________________________
OTHER SOURCES
https://neuronaldynamics.epfl.ch/online/Ch2.S2.html
britannica.com/biography/Luigi-Galvani
scientificamerican.com/article/why-does-the-brain-need-s
nobelprize.org/prizes/medicine/1906/summary
nobelprize.org/prizes/medicine/1963/summary
________________________________
LINKS TO COMMENTS
youtube.com/watch?v=TxW6_E3uLuo&lc=UgzOGpsQQvxzMJoKu8d4AaABAg
________________________________
IMAGE CREDITS
Storm Video (CC0 License):
pexels.com/video/storm-approaching-857241
Hodgkin and Huxley Portraits:
nobelprize.org/prizes/medicine/1963/summary
Public Domain Illustrations:
commons.wikimedia.org/wiki/File:Akropolis_by_Leo_von_Klenze.jpg
commons.wikimedia.org/wiki/File:Frontispiece_to_Frankenstein_1831.jpg
commons.wikimedia.org/wiki/File:Galvani_frog_legs_experiment_setup.png
commons.wikimedia.org/wiki/File:Galvani-frogs-legs-electricity.jpg
http://jv.gilead.org.il/rpaul/Vingt%20mille%20lieues%20sous%20les%20mers/
Public Domain Portraits:
commons.wikimedia.org/wiki/File:Frans_Hals_-_Portret_van_Ren%C3%A9_Descartes.jpg
commons.wikimedia.org/wiki/File:Luigi_Galvani,_oil-painting.jpg
commons.wikimedia.org/wiki/File:Alessandro_Volta.jpeg
commons.wikimedia.org/wiki/File:Jacques-Louis_David_-_Napoleon_Crossing_the_Alps_-_Kunsthistorisches_Museum.jpg
commons.wikimedia.org/wiki/File:Hans_Christian_%C3%98rsted_daguerreotype.jpg
commons.wikimedia.org/wiki/File:Ampere_Andre_1825.jpg
commons.wikimedia.org/wiki/File:Faraday-Millikan-Gale-1913.jpg
commons.wikimedia.org/wiki/File:Mary_Wollstonecraft_Shelley_Rothwell.tif
commons.wikimedia.org/wiki/File:Cajal-Restored.jpg
Clipart:
openclipart.org
commons.wikimedia.org/wiki/File:Complete_neuron_cell_diagram_en.svg
Laboratory Background:
commons.wikimedia.org/wiki/File:Interior_of_a_laboratory(GN04185).jpg
________________________________
TIME CODES
00:00 Cold Open
00:52 History of Electrophysiology
04:18 What is a Nerve?
06:23 Hodgkin-Huxley Model
10:16 Action Potentials
11:26 Bringing it all together
14:13 Outro
14:30 Sponsor Message
15:55 Featured Comment
________________________________
Corrections:
10:11 Technically, each of the circuit components of the Hodgkin-Huxley circuit do not represent a single component in the cell. It's more accurate to say the circuit components represent a population of the cell components.










