Uploaded September 2021 | Updated September 2026, 2 weeks ago
Launched by People with ALS. Clinical Trials with Biomarkers have 7x success rate, and we can find ways to include digital biomarkers in the clinical trials. This project is funded by EverythingALS with the goal to bring technology innovations to ALS. Join the fight to find a solution @Everything ALS everythingals.org/research
Launched by People with ALS. Clinical Trials with Biomarkers have 7x success rate, and we can find ways to include digital biomarkers in the clinical trials. This project is funded by EverythingALS with the goal to bring technology innovations to ALS. Join the fight to find a solution @Everything ALS everythingals.org/research



![Three Molecular Subtypes of ALS: #ExpertTalk with Dr. Molly Gale Hammell
In this episode of the EverythingALS Expert Talk Series, Dr. Molly Gale Hammell, Associate Professor at the Institute for Systems Genetics, NYU Langone Medical Center, explores the three molecular subtypes of ALS — stress, inflammation, and TDP-43 pathology. She shares insights into how these distinct pathways contribute to ALS progression and potential avenues for targeted treatments.
⏱ Timestamps:
00:00 - Introduction
02:15 - Understanding ALS at a molecular level
05:40 - The role of cellular stress in ALS
12:20 - Inflammation and its impact on disease progression
18:45 - TDP-43 pathology: Key mechanisms and implications
25:10 - Potential therapeutic strategies
30:00 - Q&A and audience discussion
About EverythingALS:
EverythingALS is a patient-focused nonprofit organization dedicated to accelerating the discovery of treatments and a cure for ALS through collaboration, innovation, and empowering patients and researchers.
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#ALS #MolecularSubtypes #TDP43 #Neurodegeneration #EverythingALS #ExpertTalk Three Molecular Subtypes of ALS: #ExpertTalk with Dr. Molly Gale Hammell](https://i.ytimg.com/vi/b8gFKRtmvqc/mqdefault.jpg)






