Uploaded January 2025 | Updated September 2026, 19 hours ago

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In this video, we look at how the oestrogen receptor acts as a transcription factor. First we explore what is meant by transcription factors and how transcription factors activate transcription of genes. We then look at the oestrogen receptor and how the shape of the oestrogen receptor changes when oestrogen binds. Finally, we look at how the oestrogen receptor acts as a transcription factor.

Image credits:

Human chromosomes
commons.wikimedia.org/wiki/File:Human_karyotype_(263_17)_Karyotype_Human,_45,XY_t13-14.jpg
Doc. RNDr. Josef Reischig, CSc., CC BY-SA 3.0 creativecommons.org/licenses/by-sa/3.0, via Wikimedia Commons

Insulin
commons.wikimedia.org/wiki/File:Insulin_struct.png
User:AtikaAtikawa, CC BY-SA 4.0 creativecommons.org/licenses/by-sa/4.0, via Wikimedia Commons

Antibody
commons.wikimedia.org/wiki/File:Antibody_IgG1_surface.png
Tokenzero, CC BY-SA 4.0 creativecommons.org/licenses/by-sa/4.0, via Wikimedia Commons

Oestrogen
commons.wikimedia.org/wiki/File:Estradiol.svg
NEUROtiker, Public domain, via Wikimedia Commons

DNA (modified as part of image of cell)
commons.wikimedia.org/wiki/File:DNA_2_--_Smart-Servier.png
Laboratoires Servier, CC BY-SA 3.0 creativecommons.org/licenses/by-sa/3.0, via Wikimedia Commons