Uploaded May 2022 | Updated September 2026, 6 hours ago

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In this episode, I discuss the observational evidence showing that vegans and vegetarians are more likely to have depression (PMID 34375207), more likely to have an inadequate iron intake (PMID 27101764), and more likely to have low body iron stores (PMID 30783404). I show that iron deficiency without anemia is a real clinical phenomenon with symptoms resembling depression (PMID 33762368, 31933400, 29881569, 28634965), and that treating with iron supplementation it results in the remission of depression (PMID 26715522). I argue that vegans should be especially careful about becoming deficient in iron and that they should be screened for iron deficiency, especially if they are premenopausal females and experiencing psychological challenges.

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