3 Ways to Build a $1M Startup with AI ft Greg Isenberg @MATGpod

Updated September 2026, 2 weeks ago

3 Ways to Build a $1M Startup with AI ft Greg Isenberg

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$From Zero To Your First AI Employee in 37 Minutes (With Hermes AI) *Build Your First AI Employee (Free Workflow + Prompt):* https://clickhubspot.com/ao2m Nick Vasilescu., co-founder of Orgo, builds a fully autonomous AI employee LIVE in one podcast — an agent that re-engages your dormant customers, drafts email sequences, runs on cron jobs, and pays for itself by tomorrow. Kieran walks through the exact 5-tool stack any marketer or operator can copy today: Orgo (the agents cloud computer), Hermes (the agent harness), GLM 5.2 (the model that costs a fraction of Claude Opus), Composio (one connector for every tool), AgentMail (the agents own inbox), and an Obsidian vault as the agents second brain. ⏱️ CHAPTERS: 00:00 — Build your first AI employee in this episode 00:40 — Meet Nick V. & Orgo: cloud computers for AI agents 02:00 — Start with a workflow, not full autonomy 03:30 — The use case: re-engage dormant customers and leads 04:40 — The stack: AgentMail, Hermes, GLM 5.2 05:20 — GLM 5.2: the DeepSeek moment for agent models 06:50 — Composio: one connector, every tool 08:20 — Why every AI agent needs its own computer 11:00 — Templates: a Hermes agent pre-installed in 20 seconds 12:00 — Why Hermes beats OpenClaw for reliability 14:40 — Do marketers still need to think in workflows? 16:30 — Loops: describe a goal, not the steps 18:00 — Model pricing: 98¢ GLM vs $5 Opus 19:20 — Wiring Composio into your Hermes agent 20:20 — Obsidian vaults: giving your agent a second brain 26:10 — AgentMail: give your agent its own inbox 27:00 — The agent builds a full re-engagement sequence live 29:10 — Safety: agent needs its own inbox, not yours 33:00 — Nicks 5-step recap of the stack 34:50 — Cloning agents: build a fleet of AI employees 36:20 — Wrap: what to build tonight Ep 433 Mentions Nick Vasilescu ⁠https://www.nickvasilescu.com Orgo ⁠https://www.orgo.ai Hermes Agent ⁠https://hermes-agent.nousresearch.com Composio ⁠https://composio.dev OpenClaw ⁠https://openclaw.ai GLM 5.2 ⁠https://z.ai/chat Obsidian ⁠https://obsidian.md 📌 WHAT WE COVER: → Why start with one workflow beats build a fully autonomous employee → The dormant-customer re-engagement play (highest-lever workflow in most businesses) → Why GLM 5.2 is the DeepSeek moment for agent models — $0.98 vs $5 for Opus → Composio: one connector that plugs your agent into every tool you already use → Why every AI agent needs its own cloud computer (and its own email inbox) → Templates in Orgo: spin up a pre-installed Hermes agent in 20 seconds → Why Hermes beats OpenClaw (Peter Steinbergers tool, acquired by OpenAI) for reliability → Loops: describe a goal, not a sequence of steps — and the agent figures it out → Kierans personal Obsidian second brain setup — the thing that changed his workflow the most → Cron jobs: how to schedule your agent to run on autopilot → The safety pattern: why your agent needs its own inbox (not yours) → Cloning agents: from one AI employee to a whole team you manage from your phone 🎙️ Host: Kieran Flanagan Guest: Nick Vasilescu., Co-founder & Head of Growth, Orgo Youtube: https://www.youtube.com/@nickvasiles Personal Website: https://www.nickvasilescu.com/ 📺 Subscribe to Marketing Against the Grain for weekly episodes on AI, growth, and marketing without the fluff. #AIemployee #AIagents #MarketingAgainstTheGrain #Orgo #HermesAgent #Composio #GLM #AIforMarketers #AItools2026 #AutonomousAgents #AgentMail #ObsidianVault #DormantCustomers #AIforBusiness #ClaudeOpus Host Links: 📲Kipp Bodnar, https://twitter.com/kippbodnar 📲Kieran Flanagan, https://twitter.com/searchbrat ‘Marketing Against The Grain’ is a HubSpot Original Podcast // Brought to you by The HubSpot Podcast Network // Produced by Darren Clarke. About the Show Kipp Bodnar, HubSpot’s CMO and Kieran Flanagan Hubspots SVP of Marketing, lead you down the rabbit hole of marketing trends, growth tactics and innovation. On the way you’ll pick up undiscovered strategies to give you that slight edge for success. These are not your typical twitter thread regurgitated marketing tactics that everyone is doing. These are new methods, with unfiltered examination of successful fresh ideas.$

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