2-Minute Neuroscience: Subarachnoid Hemorrhage @neurochallenged

Uploaded September 2025 | Updated September 2026, 2 weeks ago

Subarachnoid hemorrhage is bleeding into the subarachnoid space, the thin space between two layers of the meninges: the arachnoid mater and pia mater. Subarachnoid hemorrhage is a type of stroke and a medical emergency with a high risk of mortality. This video discusses the causes, symptoms, and treatment of subarachnoid hemorrhage.

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TRANSCRIPT
Subarachnoid hemorrhage is bleeding into the subarachnoid space, the thin space between two layers of the meninges: the arachnoid mater and pia mater. The subarachnoid space is normally filled with cerebrospinal fluid. Subarachnoid hemorrhage is a type of stroke and a medical emergency with a high risk of mortality. This video focuses on non-traumatic, or spontaneous, subarachnoid hemorrhage rather than subarachnoid hemorrhage caused by trauma, which often involves a different clinical course and treatment.

Spontaneous subarachnoid hemorrhage can be caused by a variety of conditions, but the most common and severe cases typically result from the rupture of a brain aneurysm. Subarachnoid hemorrhage usually begins suddenly, with a severe headache that develops within seconds, sometimes referred to as a thunderclap headache. Patients often describe the headache as the most severe headache they’ve ever experienced. A variety of other symptoms may also occur, including vomiting, neck pain or stiffness, loss of consciousness, or seizures.

Diagnosis typically involves a CT scan to look for blood in the subarachnoid space. If the CT scan is negative but suspicion of subarachnoid hemorrhage remains high, a lumbar puncture can be done to examine the cerebrospinal fluid for red blood cells or xanthochromia, a yellowish discoloration of cerebrospinal fluid caused by the break down of blood cells. Once subarachnoid hemorrhage has been confirmed, vascular imaging can be used to locate the source of the bleeding.

Treatment aims first to address the cause of bleeding; if an aneurysm is identified, it is typically treated to prevent blood from entering into the aneurysm. Then, patients are monitored and treated to prevent complications such as rebleeding, brain ischemia, and hydrocephalus.

REFERENCES

Claassen J, Park S. Spontaneous subarachnoid haemorrhage. Lancet. 2022 Sep 10;400(10355):846-862. doi: 10.1016/S0140-6736(22)00938-2. Epub 2022 Aug 16. PMID: 35985353; PMCID: PMC9987649.

Macdonald RL, Schweizer TA. Spontaneous subarachnoid haemorrhage. Lancet. 2017 Feb 11;389(10069):655-666. doi: 10.1016/S0140-6736(16)30668-7. Epub 2016 Sep 13. PMID: 27637674.

van Gijn J, Kerr RS, Rinkel GJ. Subarachnoid haemorrhage. Lancet. 2007 Jan 27;369(9558):306-18. doi: 10.1016/S0140-6736(07)60153-6. PMID: 17258671.

Image of CT scan from: Amato A, Britz GW, James ML, Graffagnino C, Zomorodi AR, Zomorodi ME, Olson DM. An observational pilot study of CSF diversion in subarachnoid haemorrhage. Nurs Crit Care. 2011 Sep-Oct;16(5):252-60. doi: 10.1111/j.1478-5153.2010.00444.x. Erratum in: Nurs Crit Care. 2012 Jan-Feb;17(1):56. PMID: 21824230.

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2-Minute Neuroscience: Subarachnoid Hemorrhage

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