Uploaded November 2018 | Updated September 2026, 1 week ago
The optic nerve, also known as the second cranial nerve, is responsible for transmitting visual information from the retina to the brain. In this video, I discuss the anatomy and function of the optic nerve, as well as describe what can happen when the nerve is damaged.
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TRANSCRIPT:
Welcome to 2-minute neuroscience, where I explain neuroscience topics in 2 minutes or less. In this installment I will discuss the optic nerve.
The optic nerve is a sensory nerve responsible for transmitting information about vision to the brain. The nerve begins in the retina as the axons of cells called retinal ganglion cells. These axons come together to leave the eye at a region called the optic disc and form the optic nerve.
The optic nerve leaves the eye and extends to a structure called the optic chiasm where it meets the optic nerve from the other eye. At the optic chiasm, the optic nerve fibers carrying information from the sides of the retina closest to the nose cross over to the other side of the brain, while those carrying information from the sides of the retina closest to the temples remain on the side of the brain where they are. After leaving the optic chiasm, the nerve fibers are referred to as the optic tract. Most of the nerve fibers in the optic tract end in the lateral geniculate nucleus of the thalamus, and from there the information will be passed on to the visual cortex.
Damage to the optic nerve can occur due to a variety of causes like trauma, tumors, stroke, or glaucoma. The deficit that occurs after damage depends on where the nerve is damaged, and involves some degree of visual defect or anopsia. If the damage occurs before the optic chiasm, then the patient will experience blindness in the eye supplied by that optic nerve. Damage to the middle of the optic chiasm will cause loss of the lateral visual field of both eyes, due to the way fibers from the nasal side of the retina cross over at this point. If the optic tract is damaged, one half of the visual field will be lost in both eyes.
Reference:
Vanderah TW, Gould DJ. Nolte's The Human Brain. 7th ed. Philadelphia, PA: Elsevier; 2016.
The optic nerve, also known as the second cranial nerve, is responsible for transmitting visual information from the retina to the brain. In this video, I discuss the anatomy and function of the optic nerve, as well as describe what can happen when the nerve is damaged.
🧠 Take your learning further with my free, self-paced Introduction to Neuroscience course featuring my videos, articles, and hundreds of quiz questions: neuroscientificallychallenged.com/course
If you're looking for accessible and entertaining ways to learn more about the brain, check out my books:
📚Your Brain, Explained: What Neuroscience Reveals About Your Brain and its Quirks: amazon.com/Your-Brain-Explained-Neuroscience-Reveals/dp/1473696569
📚Bizarre: The Most Peculiar Cases of Human Behavior and What They Tell Us About How the Brain Works: amazon.com/Bizarre-Peculiar-Cases-Human-Behavior/dp/139980121X
TRANSCRIPT:
Welcome to 2-minute neuroscience, where I explain neuroscience topics in 2 minutes or less. In this installment I will discuss the optic nerve.
The optic nerve is a sensory nerve responsible for transmitting information about vision to the brain. The nerve begins in the retina as the axons of cells called retinal ganglion cells. These axons come together to leave the eye at a region called the optic disc and form the optic nerve.
The optic nerve leaves the eye and extends to a structure called the optic chiasm where it meets the optic nerve from the other eye. At the optic chiasm, the optic nerve fibers carrying information from the sides of the retina closest to the nose cross over to the other side of the brain, while those carrying information from the sides of the retina closest to the temples remain on the side of the brain where they are. After leaving the optic chiasm, the nerve fibers are referred to as the optic tract. Most of the nerve fibers in the optic tract end in the lateral geniculate nucleus of the thalamus, and from there the information will be passed on to the visual cortex.
Damage to the optic nerve can occur due to a variety of causes like trauma, tumors, stroke, or glaucoma. The deficit that occurs after damage depends on where the nerve is damaged, and involves some degree of visual defect or anopsia. If the damage occurs before the optic chiasm, then the patient will experience blindness in the eye supplied by that optic nerve. Damage to the middle of the optic chiasm will cause loss of the lateral visual field of both eyes, due to the way fibers from the nasal side of the retina cross over at this point. If the optic tract is damaged, one half of the visual field will be lost in both eyes.
Reference:
Vanderah TW, Gould DJ. Nolte's The Human Brain. 7th ed. Philadelphia, PA: Elsevier; 2016.






![2-Minute Neuroscience: Color Blindness
Color blindness is a condition in which a person has difficulty seeing or distinguishing certain colors. In this video, I explain the biological mechanisms underlying color blindness and how it is inherited.
🧠 Take your learning further with my free, self-paced Introduction to Neuroscience course featuring my videos, articles, and hundreds of quiz questions: https://neuroscientificallychallenged.com/course
If youre looking for accessible and entertaining ways to learn more about the brain, check out my books:
📚Your Brain, Explained: What Neuroscience Reveals About Your Brain and its Quirks: https://www.amazon.com/Your-Brain-Explained-Neuroscience-Reveals/dp/1473696569/
📚Bizarre: The Most Peculiar Cases of Human Behavior and What They Tell Us About How the Brain Works: https://www.amazon.com/Bizarre-Peculiar-Cases-Human-Behavior/dp/139980121X/
TRANSCRIPT
Color blindness is a condition in which a person has difficulty seeing or distinguishing certain colors. It typically does not involve a complete loss of color vision. Color blindness can be due to various causes, but the most common forms are inherited and caused by genetic differences that affect the function of cone photoreceptors in the retina. The most common type of color blindness is red-green color blindness, where individuals have difficulty distinguishing red and green hues.
Normal color vision relies on three types of cones—each sensitive to different ranges of wavelengths corresponding roughly to blue, green, and red. Some individuals have all three cones but have abnormalities in cone sensitivity that cause irregularities in color perception; this is referred to as anomalous trichromacy and is the mildest form of color blindness. When only two of the three cone cells are functional, it results in a type of color blindness known as dichromacy. The rarest and most severe form of color blindness is called monochromacy and involves a complete loss of color vision.
Red-green color blindness is much more common in males because the mutations that typically cause it are found on the x chromosome. If females possess such a mutation on one x chromosome, it is likely to be balanced out by a functional gene on the other x chromosome. Because males only have one x chromosome, a mutation is more likely to result in color blindness.
Color blindness can be diagnosed using color vision tests, and although it cannot be cured, various technologies like color-enhancing lenses can help in some situations.
REFERENCES
Breedlove SM, Watson NV. Behavioral Neuroscience. 10th ed. New York (NY): Oxford University Press; 2023.
Carroll J, Conway BR. Color vision. Handb Clin Neurol. 2021;178:131-153. doi: 10.1016/B978-0-12-821377-3.00005-2. PMID: 33832674.
Meister M, Tessier‑Lavigne M. Low‑Level Visual Processing: The Retina. In: Kandel ER, Koester JD, Mack SH, Siegelbaum SA, editors. Principles of Neural Science. 6th ed. New York (NY): McGraw‑Hill; 2021.
Naifeh N, Kaufman EJ. Color Vision. 2022 Oct 31. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 29261952.
Simunovic MP. Colour vision deficiency. Eye (Lond). 2010 May;24(5):747-55. doi: 10.1038/eye.2009.251. Epub 2009 Nov 20. PMID: 19927164.
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