Nature Podcast00:46 Physicists spot new types of high-energy radiation in thunderstorms Physicists have identified new forms of γ-ray radiation created inside thunderclouds, and shown that levels of γ-ray production are much higher on Earth than previously thought.
Scientists already knew about two types of γ-ray phenomena in thunderclouds — glows that last as long as a minute and high-intensity flashes that come and go in only a few millionths of a second. Now, researchers have identified that these both occur more frequently than expected, and that previously undetected γ-ray types exist, including flickering flashes that share characteristics of the other two types of radiation.
The researchers hope that understanding more about these mysterious phenomena could help explain what initiates lightning, which often follows these γ-ray events.
10:00 Research Highlights Ancient arrowheads reveal that Europe's oldest battle likely featured warriors from far afield, and why the dwarf planet Ceres’s frozen ocean has deep impurities.
12:09 A complete wiring diagram of the fruit fly brain Researchers have published the most complete wiring diagram, or ‘connectome’ of the fruit fly’s brain, which includes nearly 140,000 neurons and 54.5 million connections between nerve cells.
The map, made from the brain of a single female fruit fly (Drosophila melanogaster), reveals over 8,400 neuron types in the brain, and has enabled scientists to learn more about the brain and how it controls aspects of fruit fly behaviour.
22:16 Briefing Chat How researchers created an elusive single-electron bond between carbon atoms, and why bigger chatbots get over-confident when answering questions.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signup
Strange gamma-ray flickers seen in thunderstorms for the first timeNature Podcast2024-10-02 | 00:46 Physicists spot new types of high-energy radiation in thunderstorms Physicists have identified new forms of γ-ray radiation created inside thunderclouds, and shown that levels of γ-ray production are much higher on Earth than previously thought.
Scientists already knew about two types of γ-ray phenomena in thunderclouds — glows that last as long as a minute and high-intensity flashes that come and go in only a few millionths of a second. Now, researchers have identified that these both occur more frequently than expected, and that previously undetected γ-ray types exist, including flickering flashes that share characteristics of the other two types of radiation.
The researchers hope that understanding more about these mysterious phenomena could help explain what initiates lightning, which often follows these γ-ray events.
10:00 Research Highlights Ancient arrowheads reveal that Europe's oldest battle likely featured warriors from far afield, and why the dwarf planet Ceres’s frozen ocean has deep impurities.
12:09 A complete wiring diagram of the fruit fly brain Researchers have published the most complete wiring diagram, or ‘connectome’ of the fruit fly’s brain, which includes nearly 140,000 neurons and 54.5 million connections between nerve cells.
The map, made from the brain of a single female fruit fly (Drosophila melanogaster), reveals over 8,400 neuron types in the brain, and has enabled scientists to learn more about the brain and how it controls aspects of fruit fly behaviour.
22:16 Briefing Chat How researchers created an elusive single-electron bond between carbon atoms, and why bigger chatbots get over-confident when answering questions.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupStar-eating black hole could power cosmic particle acceleratorNature Podcast2024-10-16 | 00:46 An unusual γ-ray producing microquasar A type of binary-system known as a microquasar has been found to be firing out γ-rays at high energy-levels, which may make it a candidate to be a long-theorized natural particle-accelerator known as a PeVatron. These objects are thought to be a source of galactic cosmic rays, the origins of which are currently a mystery.
Understanding how this microquasar works could also help researchers learn more about full-sized quasars — monstrous objects centred around supermassive black holes, which are too distant to study easily.
09:27 Research Highlights The comb jellies caught fusing their bodies, and an ancient burial site reveals that Classical accounts of Scythian culture appear to be true.
12:08 A ‘smart’ insulin-molecule that could lower hypoglycaemia risk Researchers have developed a modified insulin-molecule that varies its level of activity depending on blood-glucose levels. It’s hoped that this ‘smart’ insulin could one day help those with diabetes regulate their blood sugar more easily.
Many people with diabetes rely on regular insulin injections, but because blood-sugar levels can be difficult to predict it can be hard to select the correct dose. This can lead to hypoglycaemia — a life-threateningly low level of glucose. To overcome this, a team created a modified form of insulin with a switch that activates the molecule when glucose levels are high, and deactivates it when levels are low. This insulin-molecule was effective at maintaining correct blood glucose in animal models, and may eventually help lessen diabetes-related complications in humans.
20:33 Briefing Chat Ancient DNA confirms that infamous lions hunted humans and a variety of game, and a new technique can sequence a cell’s DNA and pinpoint its proteins, without cracking it open.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupThis AI powered tongue can tell Coke and Pepsi apartNature Podcast2024-10-09 | 00:55 Graphene Tongue Researchers have developed a graphene ‘tongue’ that uses AI to tell the subtle differences between drinks. Graphene has long been sought after as a chemical sensor, but tiny variations between devices have meant that it couldn’t be used very reliably. The team behind the ‘tongue’ got around this problem by training an AI to tell the difference between similar liquids regardless of variations between graphene devices. They hope that their work shows that it’s possible to use ‘imperfect’ chemical sensors to get accurate readings and that the ‘tongue’ will be able to help detect problems with food.
09:22 Research Highlights A 3D-printed optical microscope that can image biological samples with ultrahigh resolution, and how newly-hatched sea turtles dig their way up to the beach.
11:32 How migrating salmon move nutrients and contaminants at a continental scale Studies of migrating Pacific salmon have revealed that these animals transport thousands of tonnes of nutrients and kilograms of contaminants from the ocean to freshwater ecosystems. It’s been known that as the fish return to their freshwater spawning grounds from the sea they bring with them both nutrients and contaminants, but the impact of each has largely been studied separately. A new study combines datasets to estimate that over 40 years, the levels of nutrients these fish carry have increased at a proportionally higher rate than the contaminants, but the toxins could nevertheless be present at concerning levels to the animals that eat them.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupMysterious GAMMA-RAY flickers spotted in tropical thunderclouds ⚡️☢️⛈️Nature Podcast2024-10-05 | Did you know that tropical thunderclouds can emit invisible gamma rays?
Scientists already knew about two types of gamma-ray phenomena in clouds — long glows and momentary flashes. Now, by flying a plane over a storm, researchers have shown that these gamma-rays are much more common than we thought.
Find out more in the Nature Podcast youtube.com/watch?v=y9vrBdHhmSQAudio long read: A day in the life of the world’s fastest supercomputerNature Podcast2024-09-27 | The world's fastest supercomputer, known as Frontier, is located at the Leadership Computing Facility at Oak Ridge National Laboratory in Tennessee. This machine churns through data at record speed, outpacing 100,000 laptops working simultaneously.
With nearly 50,000 processors, Frontier was designed to push the bounds of human knowledge. It's being used to create open-source large language models to compete with commercial AI systems, simulate proteins for drug development, help improve aeroplane engine design, and more.
This is an audio version of our Feature: A day in the life of the world’s fastest supercomputer nature.com/articles/d41586-024-02832-5Children with Downs syndrome are more likely to get leukaemia: stem-cells hint at whyNature Podcast2024-09-25 | In this episode:
00:46 Unravelling why children with Down’s syndrome are at a higher risk of leukaemia Children with Down’s syndrome have a 150-fold increased risk of developing leukaemia than those without the condition. Now, an in-depth investigation has revealed that changes to genome structures in fetal liver stem-cells appear to be playing a key role in this increase.
Down’s syndrome is characterised by cells having an extra copy of chromosome 21. The team behind this work saw that in liver stem-cells — one of the main places blood is produced in a growing fetus — this extra copy results in changes in how DNA is packaged in a nucleus, opening up areas that are prone to mutation, including those known to be important in leukaemia development.
The researchers hope their work will be an important step in understanding and reducing this risk in children with Down’s syndrome.
11:47 Research Highlights How taking pints of beer off the table lowers alcohol consumption, and a small lizard’s ‘scuba gear’ helps it stay submerged.
14:12 Briefing Chat How tiny crustaceans use ‘smell’ to find their home cave, and how atomic bomb X-rays could deflect an asteroid away from a deadly Earth impact.
Science: In the dark ocean, these tiny creatures can smell their way home science.org/content/article/dark-ocean-these-tiny-creatures-can-smell-their-way-home Nature: Scientists successfully ‘nuke asteroid’ — in a lab mock-up nature.com/articles/d41586-024-03128-4The macabre wasp that lays its eggs *inside* live fruit flies 🪰Nature Podcast2024-09-21 | Drosophila fruit flies are well studied insects. For over a century, these tiny animals have been at the centre of some of the biggest molecular and genetic breakthroughs in science. But despite being under the microscope all this time, it looks like researchers have missed something. And that something is a minuscule wasp that preys on them.
This wasp species, named Syntretus perlmani, was discovered by chance in an infected fruit fly collected in a Mississippi backyard. Only a couple of millimetres long, it lays its eggs inside adult fruit flies. These eggs develop into larvae which grow and feast inside the host before bursting out to continue their lifecycle.
Despite being new to science, genomic analysis suggests its widespread across much of the US.
00:45 The biggest black hole jets ever seen Astronomers have spotted a pair of enormous jets emanating from a supermassive black hole with a combined length of 23 million light years — the biggest ever discovered. Jets are formed when matter is ionized and flung out of a black hole, creating enormous and powerful structures in space. Thought to be unstable, physicists had theorized there was a limit to how large these jets could be, but the new discovery far exceeds this, suggesting there may be more of these monstrous jets yet to be discovered.
Research Article: Oei et al. https://www.nature.com/articles/s4158...
09:44 Research Highlights The knitted fabrics designed to protect wearers from mosquito bites, and the role that islands play in fostering language diversity.
Research Highlight: Plagued by mosquitoes? Try some bite-blocking fabrics https://www.nature.com/articles/d4158...
Research Highlight: Islands are rich with languages spoken nowhere else https://www.nature.com/articles/d4158...
12:26 A sustainable, one-step method for alloy production Making metal alloys is typically a multi-step process that creates huge amounts of emissions. Now, a team demonstrates a way to create these materials in a single step, which they hope could significantly reduce the environmental burdens associated with their production. In a lab demonstration, they use their technique to create an alloy of nickel and iron called invar — a widely-used material that has a high carbon-footprint. The team show evidence that their method can produce invar to a quality that rivals that of conventional manufacturing, and suggest their technique is scalable to create alloys at an industrial scale.
Research article: Wei et al. https://www.nature.com/articles/s4158...
25:29 Briefing Chat How AI-predicted protein structures have helped chart the evolution of a group of viruses, and the neurons that cause monkeys to ‘choke’ under pressure.
Nature News: Where did viruses come from? AlphaFold and other AIs are finding answers https://www.nature.com/articles/d4158...
Nature News: Why do we crumble under pressure? Science has the answer https://www.nature.com/articles/d4158...These black hole jets are HUNDREDS of Milky Way galaxies long 🕳️Nature Podcast2024-09-19 | Black holes are often thought of in terms of sucking things in, but in some cases they also fling stuff out as well. When this happens matter gets ionized and fired out from the top and bottom of the black holes. These violent and powerful phenomena are known as black hole jets. The biggest of these are made by supermassive black holes and can be up to several million light years in size. And now a team has seen the biggest yet. It’s around 7 megaparsecs, or 23 million light years, in size.
To put that another way, if you take the Milky Way as being 100,000 light years across then that's like 233 milky way galaxies stacked on top of each other end to end. That is a full six and a half million light years bigger than the maximum size astronomers theorised these jets to be.
00:45 What ancient DNA has revealed about Rapa Nui’s past Ancient DNA analysis has further demonstrated that the people of Rapa Nui did not cause their own population collapse, further refuting a controversial but popular claim. Rapa Nui, also known as Easter island, is famous for its giant Moai statues and the contested idea that the people mismanaged their natural resources leading to ‘ecological suicide’. Genomes sequenced from the remains of 15 ancient islanders showed no evidence of a sudden population crash, substantiating other research challenging the collapse idea.
19:29 A macabre parasite of adult fruit flies Despite being a hugely-studied model organism, it seems that there’s still more to find out about the fruit fly Drosophila melanogaster, as researchers have discovered a new species of parasitoid wasp that infects the species. Unlike other parasitic wasps, this one lays its eggs in adult flies, with the developing larva devouring its host from the inside. The miniscule wasp was discovered by chance in an infected fruit fly collected in a Mississippi backyard and analysis suggests that despite having never been previously identified, it is widespread across parts of North America.
32:04 Briefing Chat How a dye that helps to give Doritos their orange hue can turn mouse tissues transparent, and an effective way to engage with climate-science sceptics.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. nature.com/briefing/signupThe baseless stat that could be harming Indigenous conservation effortsNature Podcast2024-09-06 | The often repeated claim that "80% of the world's biodiversity is found in the territories of Indigenous Peoples" appears widely in policy documents and reports, yet appears to have sprung out of nowhere. According to a group of researchers, including those from Indigenous groups, this baseless statistic could be undermining the conservation efforts of the Indigenous People it's meant to support and prevent further work to really understand how best to conserve biodiversity.
Two of the authors joined us to discuss how this statistic may have come about, the harm it could cause, and how better to support the work of Indigenous Peoples.
Read more in a Comment article from the authors: No basis for claim that 80% of biodiversity is found in Indigenous territories nature.com/articles/d41586-024-02811-w
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupLong-sought nuclear clocks are one tick closerNature Podcast2024-09-04 | 00:45 Why a 'nuclear clock' is now within researchers’ reach Researchers have made a big step towards the creation of the long theorized nuclear clock, by getting the most accurate measurement of the frequency of light required to push thorium nuclei into a higher energy state. Such a timekeeper would differ from the best current clocks as their ‘tick’ corresponds to the energy transitions of protons and neutrons, rather than electrons. Nuclear clocks have the potential to be more robust and accurate than current systems, and could offer researchers new insights into fundamental forces present within atomic nuclei.
10:10 Research Highlights The star that got partially shredded by a supermassive black hole, not just once, but twice, and how heatwaves could mangle bumblebees’ sense of smell.
12:11 How engineered immune cells could help limit damage after spinal injury By harnessing T cells to fine-tune the inflammation response, researchers have limited the damage caused by spinal injury in mice, an approach they hope might one day translate into a human therapy. Following injury to the central nervous system, immune cells rush to the scene, resulting in a complex array of effects, both good and bad. In this work researchers have identified the specific kind of T cells that amass at the site, and used them to create an immunotherapy that helps the mice recover more quickly from injuries by slowing damage to neurons.
20:36 Briefing Chat How unprecedented floods in Brazil have helped and hindered paleontologists, and the ‘AI scientist’ that does everything from literature review through to manuscript writing, to an extent.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupAudio long read: So you got a null result. Will anyone publish it?Nature Podcast2024-08-30 | The 'file-drawer problem', where findings with null or negative results gather dust and are left unpublished, is well known in science. There has been an overriding perception that studies with positive or significant findings are more important, but this bias can have real-world implications, skewing perceptions of drug efficacies, for example.
Multiple efforts to get negative results published have been put forward or attempted, with some researchers saying that the incentive structures in academia, and the ‘publish or perish’ culture, need to be overturned in order to end this bias.
This is an audio version of our Feature: So you got a null result. Will anyone publish it? nature.com/articles/d41586-024-02383-9Covert racism in AI chatbots, precise Stone Age engineering, and the science of paper cutsNature Podcast2024-08-28 | 00:31 Chatbots makes racist judgements on the basis of dialect
Research has shown that large language models, including those that power chatbots such as ChatGPT, make racist judgements on the basis of users’ dialect. If asked to describe a person, many AI systems responded with racist stereotypes when presented with text written in African American English — a dialect spoken by millions of people in the United States that is associated with the descendants of enslaved African Americans — compared with text written in Standardized American English. The findings show that such models harbour covert racism, even when they do not display overt racism, and that conventional fixes to try and address biases in these models had no effect on this issue.
07:01 How ancient engineers built a megalithic structure
The 6,000-year-old Dolmen of Menga is a marvel of ancient engineering. New research reveals new insights into the structure and the technical abilities of the Neolithic builders who constructed it. The work shows that a setup of counterweights and ramps may have been used to correctly position the massive sandstone blocks that make up walls of the structure, which were each tilted at precise, millimetre-scale angles. The researchers suggest that this construction shows that the Neolithic people who built the dolmen had a working understanding of physics, geometry, geology and architectural principles.
Orb-weaving spiders (Araneus ventricosus) use ensnared male Absocondita terminalis fireflies to trick more insects into their web. A bite from the spider causes the flashing pattern of the trapped firefly to shift to one resembling a female looking to mate, leading others into an ambush. Exactly how this system works is unclear, but researchers say it is a rare example of a predator altering the behaviour of its prey to catch others.
By combining experiments and theoretical work, a team has unraveled the mystery of why only certain types of paper can cut into human skin. Their work shows that paper that is too thin will buckle without cutting, while paper that’s too thick will distribute force over a relatively large area without inflicting damage. The research suggests that the sweet spot for slicing is paper with around 65 micrometres in thickness, which includes the kind used to print certain high-profile journals…
Research Highlight: What Science and Nature are good for: causing paper cuts nature.com/articles/d41586-024-02297-6Can ageing be stopped? A biologist explainsNature Podcast2024-08-22 | For millennia, humanity has obsessed about halting ageing and, ultimately, preventing death. Yet while advances in medicine and public-health have seen human life-expectancy more than double, our maximum lifespan stubbornly remains around 120 years.
On the latest episode of 'Nature hits the books', Nobel laureate Venki Ramakrishnan joins us to discuss what scientists have learnt about the molecular processes underlying ageing, whether they can be prevented, and why the quest for longevity also need to consider the health-related issues associated with old age.
Why We Die: The New Science of Ageing and the Quest for Immortality Venki Ramakrishnan Hodder (2024)
Music supplied by Airae/Epidemic Sound/Getty images.AI cant learn new things forever — an algorithm can fix thatNature Podcast2024-08-21 | 00:46 Old AIs can’t learn new tricks
An algorithm that reactivates dormant ‘neurons’ in deep learning based AIs could help them overcome their inability to learn new things and make future systems more flexible, research has shown. AIs based on deep learning struggle to learn how to tackle new tasks indefinitely, making them less adaptable to new situations. The reasons for this are unclear, but now a team has identified that ‘resetting’ parts of the neural networks underlying these systems can allow deep learning methods to keep learning continually.
08:55 Research Highlights To stop crocodiles eating poisonous toads researchers have been making them sick, and a sacrificed child in ancient Mexico was the progeny of closely related parents.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupThe mystery of Stonehenges central stone unearthedNature Podcast2024-08-14 | 00:48 The mystery of Stonehenge’s Altar Stone Stonehenge’s central stone came from Northern Scotland, more than 600 miles away from the monument, according to a new analysis of its geochemistry. It is commonly accepted that many of the rocks that make up the iconic neolithic monument came from Wales, 150 miles from the site. Previously, it had been thought that a central stone, called the Altar Stone, had also come from this area, known as the Preseli Hills. The new work suggests that the ancient Britons went much further, perhaps ferrying the Altar Stone hundreds of miles, to place the rock at the centre of Stonehenge.
14:13 A new way to break bonds Chemists have demonstrated a way to break Selenium-Selenium bonds unevenly, something they have been trying for decades. Chemical bonds have to be broken and reformed to create new compounds, but they often don’t break in a way that allows chemists to form new bonds in the ways they would like. Breaks are often ‘even’, with electrons shared equally between atoms. To prevent such an even split, a team used a specific solvent and a combination of light and heat to force the selenium bonds to break unevenly. This could potentially open up ways to create compounds that have never been made before.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupChatGPT has a language problem — but science can fix itNature Podcast2024-08-09 | AIs built on Large Language Models have wowed by producing particularly fluent text. However, their ability to do this is limited in many languages. As the data and resources used to train a model in a specific language drops, so does the performance of the model, meaning that for some languages the AIs are effectively useless.
Researchers are aware of this problem and are trying to find solutions, but the challenge extends far beyond just the technical, with moral and social questions to be answered. This podcast explores how Large Language Models could be improved in more languages and the issues that could be caused if they are not.
Watch our related video of people trying out ChatGPT in different languages: youtube.com/watch?v=bgjVJHp0W28Where weird plants thrive: aridity spurs diversity of traitsNature Podcast2024-08-07 | 00:48 Plant trait diversity in drylands A study reveals that, unexpectedly, plants display a greater diversity of traits in drier environments. Trait diversity is a measure of an organism's performance in an environment and can include things like the size of a plant or its photosynthetic rate. Whilst there are good data on this kind of diversity in temperate regions, an assessment of drylands has been lacking. The new study fills this knowledge gap and finds that, counter to a prevailing expectation that fewer traits would be displayed, at a certain level of aridity trait diversity doubles. The team behind the new work hope that it can help us better protect biodiversity as the planet warms and areas become drier.
10:59 The Great Barrier Reef is the hottest it’s been for centuries An assessment of coral skeletons has shown that the past decade has been the warmest for the Great Barrier Reef for 400 years. By looking at the chemical composition of particularly old specimens of coral in the reef, researchers were able to create a record of temperatures going back to 1618. In addition to showing recent record breaking temperatures they also developed a model that suggests that such temperatures are very unlikely to occur without human-induced climate change. Altogether, the study suggests that the reef is in dire straits and much of the worlds’ coral could be lost.
18:56 ‘Publish or Perish’ becomes a card game Most researchers are familiar with the refrain ‘Publish or Perish’ — the idea that publications are the core currency of a scientist’s career — but now that can be played out for laughs in a new board game. Created as a way to help researchers “bond over shared trauma”, the game features many mishaps familiar to academics, scrambles for funding and scathing comments, all while players must compete to get the most citations on their publications. Reporter Max Kozlov set out to avoid perishing and published his way to a story about the game for the Nature Podcast.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupHow light-based computers could cut AI’s energy needsNature Podcast2024-07-31 | 00:45 Increasing the energy efficiency of light-based computers Computer components based on specialised LEDs could reduce the energy consumption of power hungry AI systems, according to new research. AI chips with components that compute using light can run more efficiently than those using digital electronics, but these light-based systems typically use lasers that can be bulky and difficult to control. To overcome these obstacles, a team has developed a way to replace these lasers with LEDs, which are cheaper and more efficient to run. Although only a proof of concept, they demonstrate that their system can perform some tasks as well as laser-based computers.
13:02 What researchers know about H5N1 influenza in cows The highly-pathogenic avian influenza H5N1 was first identified in US cattle in March 2024 and has been detected in multiple herds across the country. We round up what researchers currently know about this spread, what can be done to prevent it, and the risks this outbreak may pose to humans.
22:38 Briefing Chat NASA’s Perseverance rover finds a Martian rock containing features associated with fossilized microbial life, and how metallic nodules on the ocean floor could be the source of mysterious ‘dark oxygen’
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupAudio long read: Hope, despair and CRISPR — the race to save one woman’s lifeNature Podcast2024-07-26 | In India, a group of researchers raced to develop a CRISPR-based genome editing therapy to save the life of a young woman with a rare neurodegenerative disease. Despite a valiant effort, the pace of research was ultimately too slow to save her life. While many are convinced that these therapies could offer hope to those with overlooked genetic conditions, it will likely take years to develop the techniques needed to quickly create bespoke treatments, something people in need don't have.
This is an audio version of our Feature: Hope, despair and CRISPR — the race to save one woman’s life nature.com/articles/d41586-024-01716-yRapid sepsis test identifies bacteria that spark life-threatening infectionNature Podcast2024-07-24 | 00:48 A rapid way to identify serious bacterial infections A newly-developed method that can rapidly identify the type of bacteria causing a blood-infection, and the correct antibiotics to treat it, could save clinicians time, and patient lives. Blood infections are serious, and can lead to the life-threatening condition sepsis, but conventional diagnostic methods can take days to identify the causes. This new method does away with some of the time-consuming steps, and the researchers behind it say that if it can be fully automated, it could provide results in less than a day.
11:49 Research Highlights The discovery of a connection between three star-forming interstellar clouds could help explain how these giant structures form, and evidence of the largest accidental methane leak ever recorded.
14:22 AIs fed AI-generated text start to spew nonsense When artificial intelligences are fed data that has itself been AI-generated, these systems quickly begin to spout nonsense responses, according to new research. Typically, large language model (LLM) AI’s are trained on human-produced text found online. However, as an increasing amount of online content is AI-generated, a team wanted to know how these systems would cope. They trained an AI to produce Wikipedia-like entries, then trained new iterations on the model on the text produced by its predecessor. Quickly the outputs descended into gibberish, which highlights the dangers of the Internet becoming increasingly full of AI-generated text.
25:49 Briefing Chat How psilocybin — the hallucinogenic compound found in magic mushrooms — resets communication between brain regions, and the surprise cancellation of a NASA Moon mission. Nature News: Your brain on shrooms — how psilocybin resets neural networks nature.com/articles/d41586-024-02275-y
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupThe plastic that biodegrades in your home compostNature Podcast2024-07-17 | 01:04 A gel to safely transport proteins A gel that encases proteins could be a new way to safely transport medicines without requiring them to be kept cold, according to new research. To test it, the team behind the work posted themselves a protein suspended in this gel, showing that it was perfectly preserved and retained its activity, despite being dropped in transit and exposed to varying temperatures. The researchers hope this gel will help overcome the need to freeze protein-based medicines, which can be expensive to do and difficult to maintain during transportation.
08:51 Research Highlights How an abundance of cicadas led to a host of raccoon activity, and how wine-grape harvest records can be used to estimate historical summertime temperatures
11:24 Making a plastic biodegradable By embedding a plastic with an engineered enzyme, researchers have developed a fully biodegradable material that can be broken down in a home compost heap. Plastic production often requires high temperatures, so the team adapted an enzyme to make it more able to withstand heat, while still able to break down a common plastic called PLA. They hope this enzyme-embedded plastic could replace current single-use items, helping to reduce the huge amount of waste produced each year.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupBreastfeeding should break down mothers bones — heres why it doesntNature Podcast2024-07-10 | 00:45 In situ editing of the gut microbiome Researchers have developed a method to directly edit the genes of specific bacteria in the guts of live mice, something that has previously been difficult to accomplish due to the complexity of this environment. The tool was able to edit over 90% of an E. coli strain colonising mice guts, with other work showing the tool could be used to edit genes in pathogenic bacterial species and strains. It is hoped that with further research this technique could be adapted to work in humans, potentially altering bacteria associated with disease.
06:56 Research Highlights The ants that perform life-saving surgery on their nest-mates, and why amber’s scarcity led ancient artisans to make imitation jewellery.
08:46 How is bone health maintained during breastfeeding? During breastfeeding bones are stripped of calcium, while levels of oestrogen — which normally helps keep them healthy — drop off precipitously. This puts bones under tremendous stress, but why they don’t break down at this time has proved a mystery. Now, a team has identified a hormone produced in lactating mice that promotes the build up of bones, keeping them strong during milk production. Injecting this hormone into injured mice helped their bones heal faster, and the team hopes that their finding could ultimately help treat bone-weakening conditions like osteoporosis in humans.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupThese frog saunas’ could help endangered species fight off a deadly fungusNature Podcast2024-07-03 | 00:47 Searching for dark matter in black holes Researchers have been scanning the skies looking for black holes that formed at the very beginning of the Universe — one place where elusive and mysterious dark matter is thought to be located. If these black holes did contain dark matter, they would be especially massive and so researchers would be able to see the bending of light as they pass in front of stars. Such events would be rare, so to find them researchers trawled through a decades-long dataset. However, despite the large number of observations, the researchers didn't find many examples of these events and none that were long enough to show signs of much dark matter. So, the hunt for enigmatic material goes on.
09:42 Research Highlights How some comb jellies survive the crushing ocean depths, and how giving cash to mothers in low-income households can boost time and money spent on children.
12:39 A simple, solution to tackle a deadly frog disease A simple ‘sauna’ built of bricks and a supermarket-bought greenhouse, can help frogs rid themselves of a devastating fungal disease, new research has shown. While options to prevent or treat infection are limited, the fungus that causes the disease chytridiomycosis has an achilles heel: it can’t survive at warm temperatures. A team in Australia used this knowledge to their advantage to develop saunas where frogs can warm themselves to clear an infection. Frogs who spent time in these hot environments were able to shake the fungus, and gained some immunity to subsequent infections. While this research only involved one type of frog, it offers some hope in tackling a deadly disease that has driven multiple species to extinction.
20:06 Briefing Chat This time, we discuss what the upcoming UK election could mean for science, and the return of rock samples from the Moon’s far side.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupAudio long read: How NASA astronauts are training to walk on the Moon in 2026Nature Podcast2024-06-28 | In 2026, NASA aims to send humans back to the Moon's surface, as part of the Artemis III mission. In preparation, astronauts have been performing moonwalking simulations to ensure that they are able to make the most of their precious time on the lunar surface. In one dress rehearsal, a pair of astronauts took part in a training exercise in an Arizona volcanic field, working with a science team to practice doing geology work in difficult conditions designed to mimic some that will be experienced at the lunar south pole.
Image credit: NASA/Josh ValcarcelWhy ‘open source’ AIs could be anything but, the derailment risks of long freight trains, and bre...Nature Podcast2024-06-26 | 00:31 How open are ‘open source’ AI systems?Many of the large language models powering AI systems are described as ‘open source’ but critics say this is a misnomer, with restricted access to code and training data preventing researchers from probing how these systems work. While the definition of open source in AI models is yet to be agreed, advocates say that ‘full’ openness is crucial in efforts to make AI accountable. New research has ranked the openness of different systems, showing that despite claims of ‘openness’ many companies still don’t disclose a lot of key information.
Nature News: Not all ‘open source’ AI models are actually open: here’s a ranking06:12 Why longer freight trains are more prone to derailmentIn the US, there are no federal limits on the length of a freight train, but as companies look to run longer locomotives, questions arise about whether they are at greater risk of derailment. To find out, a team analysed data on accidents to predict the chances of longer trains coming off the tracks. They showed that replacing two 50-car freight trains with one 100-car train raises the odds of derailment by 11%, with the chances increasing the longer a train gets. While derailments are uncommon, this could change as economic pressures lead the freight industry to experiment with ever-longer trains.
Scientific American: Longer and Longer Freight Trains Drive Up the Odds of Derailment11:44 How historic wheat could give new traits to current cropsGenes from century-old wheat varieties could be used to breed useful traits into modern crops, helping them become more disease tolerant and reducing their need for fertiliser. Researchers sequenced the genomes of hundreds of historic varieties of wheat held in a seed collection from the 1920s and 30s, revealing a huge amount of genetic diversity unseen in modern crops. Plant breeding enabled the team to identify some of the areas of the plants’ genomes responsible for traits such as nutritional content and stress tolerance. It’s hoped that in the long term this knowledge could be used to improve modern varieties of wheat.
Science: ‘Gold mine’ of century-old wheat varieties could help breeders restore long lost traits
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.How do fish know where a sound comes from? Scientists have an answerNature Podcast2024-06-21 | 00:46 How light touches are sensed during sex 150 years after they were discovered, researchers have identified how specific nerve-cell structures on the penis and clitoris are activated. While these structures, called Krause corpuscles, are similar to touch-activated corpuscles found on people’s fingers and hands, there was little known about how they work, or their role in sex. Working in mice, a team found that Krause corpuscles in both male and females were activated when exposed to low-frequency vibrations and caused sexual behaviours like erections. The researchers hope that this work could help uncover the neurological basis underlying certain sexual dysfunctions.
07:03 Research Highlights Astronomers struggle to figure out the identity of a mysterious object called a MUBLO, and how CRISPR gene editing could make rice plants more water-efficient.
09:21 How fish detect the source of sound It’s long been understood that fish can identify the direction a sound came from, but working out how they do it is a question that’s had scientists stumped for years. Now using a specialist setup, a team of researchers have demonstrated that some fish can independently detect two components of a soundwave — pressure and particle motion — and combine this information to identify where a sound comes from.
20:30: Briefing Chat Ancient DNA sequencing reveals secrets of ritual sacrifice at Chichén Itzá, and how AI helped identify the names that elephants use for each other.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupHybrid working works: huge study reveals no drop in productivityNature Podcast2024-06-12 | 00:48 Short-haul spaceflight's effect on the human body. A comprehensive suite of biomedical data, collected during the first all-civilian spaceflight, is helping researchers unpick the effects that being in orbit has on the human body. Analysis of data collected from the crew of SpaceX’s Inspiration4 mission reveals that short duration spaceflight can result in physiological changes similar to those seen on longer spaceflights. These changes included things like alterations in immune-cell function and a lengthening of DNA telomeres, although the majority of these changes reverted soon after the crew landed.
12:13 Research Highlights Researchers have discovered why 2019 was so awash with Painted Lady butterflies, and the meaning behind gigantic rock engravings along the Orinoco river.
14:55 The benefits of working from home, some of the time A huge trial of hybrid working has shown that this approach can help companies retain employees without hurting productivity. While a mix of home and in-person working became the norm for many post-pandemic, the impacts of this approach on workers’ outputs remains hotly debated and difficult to test scientifically. To investigate the effects of hybrid working, researchers randomly selected 1,612 people at a company in China to work in the office either five days a week or three. In addition to the unchanged productivity, employees said that they value the days at home as much as a 10% pay rise. This led to an increase in staff retention and potential savings of millions of dollars for the company involved in the trial.
25:50: Briefing Chat Germany balks at the $17 billion bill for CERN’s new supercollider, and working out when large language models might run out of data to train on.
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Subscribe to Nature Briefing: AI and Robotics: nature.com/briefing/ai-roboticsTwitter suspended 70,000 accounts after the Capitol riots and it curbed misinformationNature Podcast2024-06-05 | 00:46 Making a molecular Bose-Einstein condensate For the first time, researchers have coaxed molecules into a bizarre form of matter called a Bose-Einstein condensate, in which they all act in a single gigantic quantum state. While condensates have been made using atoms for decades, the complex interactions of molecules have prevented them from being cooled into this state. Now, a team has successfully made a Bose-Einstein condensate using molecules made of caesium and sodium atoms, which they hope will allow them to answer more questions about the quantum world, and could potentially form the basis of a new kind of quantum computer.
9:57 How deplatforming affects the spread of social media misinformation The storming of the US Capitol on 6 January 2021 resulted in the social media platform Twitter (now X) rapidly deplatforming 70,000 users deemed to be sharers of misinformation. To evaluate the effect of this intervention, researchers analysed the activity of over 500,000 Twitter users, showing that it reduced the sharing of misinformation, both from the deplatformed users and from those who followed them. Results also suggest that other misinformation traffickers who were not deplatformed left Twitter following the intervention. Together these results show that social media platforms can curb misinformation sharing, although a greater understanding of the efficacy of these actions in different contexts is required.
20:14: Briefing Chat A new antibiotic that can kill harmful bacteria without damaging the gut microbiome, and the tiny plant with the world’s biggest genome.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupHow AI could improve robotics, the cockroach’s origins, and promethium spills its secretsNature Podcast2024-05-29 | In this episode: 00:25 What the rise of AI language models means for robots Companies are melding artificial intelligence with robotics, in an effort to catapult both to new heights. They hope that by incorporating the algorithms that power chatbots it will give robots more common-sense knowledge and let them tackle a wide range of tasks. However, while impressive demonstrations of AI-powered robots exist, many researchers say there is a long road to actual deployment, and that safety and reliability need to be considered.
16:09 How the cockroach became a ubiquitous pest Genetic research suggests that although the German cockroach (Blattella germanica) spread around the world from a population in Europe, its origins were actually in South Asia. By comparing genomes from cockroaches collected around the globe, a team could identify when and where different populations might have been established. They show that the insect pest likely began to spread east from South Asia around 390 years ago with the rise of European colonialism and the emergence of international trading companies, before hitching a ride into Europe and then spreading across the globe.
20:26: Rare element inserted into chemical 'complex' for the first time Promethium is one of the rarest and most mysterious elements in the periodic table. Now, some eight decades after its discovery, researchers have managed to bind this radioactive element to other molecules to make a chemical ‘complex’. This feat will allow chemists to learn more about the properties of promethium filling a long-standing gap in the textbooks.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. nature.com/briefingHow mathematician Freeman Hrabowski opened doors for Black scientistsNature Podcast2024-05-28 | Growing up in Alabama in the 1960s, mathematician Freeman Hrabowski was moved to join the civil rights moment after hearing Martin Luther King Jr speak. Even as a child, he saw the desperate need to make change. He would go on to do just that — at the University of Maryland Baltimore County, where he co-founded the Meyerhoff Scholars Program, one of the leading pathways to success for Black students in STEM subjects in the United States.
Freeman is the subject of the first in a new series of Q&As in Nature celebrating ‘Changemakers’ in science — individuals who fight racism and champion inclusion. He spoke to us about his about his life, work and legacy.
Career Q&A: I had my white colleagues walk in a Black student’s shoes for a dayAudio long read: How does ChatGPT ‘think’? Psychology and neuroscience crack open AI LLMsNature Podcast2024-05-24 | AIs are often described as 'black boxes' with researchers unable to to figure out how they 'think'. To better understand these often inscrutable systems, some scientists are borrowing from psychology and neuroscience to design tools to reverse-engineer them, which they hope will lead to the design of safer, more efficient AIs.
This is an audio version of our Feature: How does ChatGPT ‘think’? Psychology and neuroscience crack open AI large language models nature.com/articles/d41586-024-01314-y
Image credit: Gabby Jones/Bloomberg/GettyFentanyl addiction: the brain pathways behind the opioid crisisNature Podcast2024-05-22 | 00:45 The neuroscience of fentanyl addiction Research in mice has shown that fentanyl addiction is the result of two brain circuits working in tandem, rather than a single neural pathway as had been previously thought. One circuit underlies the positive feelings this powerful drug elicits, which the other was responsible for the intense withdrawal when it is taken away. Opioid addiction leads to tens of thousands of deaths each year, and the team hopes that this work will help in the development of drugs that are less addictive.
09:16 Research Highlights How an ‘assembloid’ could transform how scientists study drug delivery to the brain, and an edible gel that prevents and treats alcohol intoxication in mice.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupLizard-inspired building design could save livesNature Podcast2024-05-15 | In this episode: 00:45 A recyclable 3D printing resin from an unusual source Many 3D printers create objects using liquid resins that turn into robust solids when exposed to light. But many of these are derived from petrochemicals that are difficult to recycle. To overcome this a team has developed a new type of resin, which they’ve made using a bodybuilding supplement called lipoic acid. Their resin can be printed, recycled and reused multiple times, which they hope could in future contribute to reducing waste associated with 3D printing.
12:27 To learn how to make safe structures researchers... destroyed a building
Many buildings are designed to prevent collapse by redistributing weight following an initial failure. However this relies on extensive structural connectedness that can result in an entire building being pulled down. To prevent this, researchers took a new approach inspired by the ability of some lizards to shed their tails. They used this to develop a modular system, which they tested by building — and destroying — a two storey structure. Their method stopped an initial failure from spreading, preventing a total collapse. The team hope this finding will help prevent catastrophic collapses, reducing loss of life in aid rescue efforts.
An AI algorithm discovers 27,500 new asteroids, and an exquisitely-accurate map of a human brain section reveals cells with previously undiscovered features.
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00:45 A nuclear timekeeper that could transform fundamental-physics research. Nuclear clocks — based on tiny shifts in energy in an atomic nucleus — could be even more accurate and stable than other advanced timekeeping systems, but have been difficult to make. Now, a team of researchers have made a breakthrough in the development of these clocks, identifying the correct frequency of laser light required to make this energy transition happen. Ultimately it’s hoped that physicists could use nuclear clocks to probe the fundamental forces that hold atoms together.
13:48 AlphaFold gets an upgrade Deepmind’s AlphaFold has revolutionised research by making it simple to predict the 3D structures of proteins, but it has lacked the ability to predict situations where a protein is bound to another molecule. Now, the AI has been upgraded to AlphaFold 3 and can accurately predict protein-molecule complexes containing DNA, RNA and more. Whilst the new version is restricted to non-commercial use, researchers are excited by its greater range of predictive abilities and the prospect of speedier drug discovery.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: nature.com/briefing/signupDads microbiome can affect offsprings health — in miceNature Podcast2024-05-01 | In this episode: 00:46 Using genomics to explain geographic differences in cancer risk The risk of developing cancer can vary hugely depending on geographic region, but it’s not exactly clear why. To get a better idea, a team has compared the genomes of kidney cancers taken from people around the globe. They reveal a link between geographical locations and specific genetic mutations, suggesting that there are as-yet unknown environmental or chemical exposures in different locations. They hope this work will inform public health efforts to identify and reduce potential causes of cancer.
07:46 Research Highlights Research reveals that the extinct ‘sabre-toothed salmon’ actually had tusks, and a common fungus that can clean up both heavy-metal and organic pollutants.
09:55 How disrupting a male mouse’s microbiome affects its offspring Disruption of the gut microbiota has been linked to issues with multiple organs. Now a team show disruption can even affect offspring. Male mice given antibiotics targeting gut microbes showed changes to their testes and sperm, which lead to their offspring having a higher probability of severe growth issues and premature death. Although it’s unknown whether a similar effect would be seen in humans, it suggests that factors other than genetics play a role in intergenerational disease susceptibility.
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: go.nature.com/get-the-nature-briefingSex and gender discussions dont need to be toxicNature Podcast2024-05-01 | Ever since scientific enquiry began, people have focused mainly on men, or if studies involve animals, on male mice, male rats or whatever it may be. And this has led to gaps in scientists’ understanding of how diseases, and responses to treatment, and many other things might vary between people of different sexes and genders.
These days, mainly thanks to big funders like the NIH introducing new guidelines and mandates, a lot more scientists are thinking about sex and, where appropriate, gender. And this has led to a whole host of discoveries.
But all this research is going on within a sociopolitical climate that’s becoming increasingly hostile and polarized, particularly in relation to gender identity. And in some cases, science is being weaponized to push agendas, creating confusion and fear.
It is clear that sex and gender exist beyond a simple binary. This is widely accepted by scientists and it is not something we will be debating in this podcast. But this whole area is full of complexity, and there are many discussions which need to be had around funding, inclusivity or research practices.
To try to lessen fear, and encourage clearer, less divisive thinking, today, we have asked three contributors to a special series of opinion pieces on sex and gender - Florence Ashley, Margaret McCarthy and Stacey Ritz - to come together and thrash out how exactly scientists can fill in years of neglected research – and move forward with exploring the differences between individuals in a way that is responsible, inclusive and beneficial to as many people as possible.
Read more in the collection: nature.com/immersive/sex-and-gender-in-science/index.htmlAudio long read: Why loneliness is bad for your healthNature Podcast2024-04-26 | Many people around the world feel lonely. Chronic loneliness is known to have far-reaching health effects and has been linked to multiple conditions and even early death. But the mechanisms through which feeling alone can lead to poor health is a puzzle. Now, researchers are looking at neurons in the hopes that they may help explain why health issues arise when social needs go unmet.
Image credit: Richard Baker/In Pictures/GettyHow gliding marsupials got their wingsNature Podcast2024-04-24 | In this episode: 00:46 Optical clocks at sea Optical atomic clocks are the most precise timekeeping devices on the planet, but these devices are huge and difficult to work with, limiting their use outside of the lab. Now, researchers have developed a portable optical clock and demonstrated its robustness by sending it on a perilous sea journey. The team hope that this work will pave the way to more practical uses of optical clocks, such as on satellites where they could help improve the accuracy of GPS technologies.
09:34 Research Highlights Evidence of ritual burning of the remains of a Maya royal family, and the first solid detection of an astrophysical tau-neutrino.
11:52 How marsupial gliding membranes evolved Several marsupial species have evolved a membrane called a patagium that allows them to glide gracefully from tree to tree. Experiments show that mutations in areas of DNA around the gene Emx2 were key to the evolution of this ability, which has appeared independently in multiple marsupial species.
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Image credit: : Auscape International/AlamyLiving on Mars would probably suck — heres whyNature Podcast2024-04-19 | Humans setting up home in outer space has long been the preserve of science fiction. Now, thanks to advances in technology and the backing of billionaires, this dream could actually be realised. But is it more likely to be a nightmare?
Kelly and Zach Weinersmith join us to discuss their new book A City on Mars and some of the medical, environmental and legal roadblocks that may prevent humanity from ultimately settling in space.
A City on Mars: Can We Settle Space, Should We Settle Space, and Have We Really Thought This Through? Kelly and Zach Weinersmith Particular Books (2023)
Image credit: Zach WeinersmithKeys, wallet, phone: the neuroscience behind working memoryNature Podcast2024-04-17 | In this episode:
00:46 Mysterious methane emission from a cool brown dwarf The James Webb Space Telescope (JWST) is revealing the makeup of brown dwarfs — strange space objects that blur the line between a planet and a star. And it appears that methane in the atmosphere of one of these objects, named W1935, is emitting infrared radiation. Where the energy comes from is a mystery however, researchers hypothesise that the glow could be caused by an aurora in the object’s atmosphere, perhaps driven by an as-yet unseen moon.
10:44 Research Highlights The discovery that bitter taste receptors may date back 450 million years, and the first planet outside the Solar System to boast a rainbow-like phenomenon called a ‘glory’.
13:07 How working memory works Working memory is a fundamental process that allows us to temporarily store important information, such as the name of a person we’ve just met. However distractions can easily interrupt this process, leading to these memories vanishing. By looking at the brain activity of people doing working-memory tasks, a team have now confirmed that working memory requires two brain regions: one to hold a memory as long as you focus on it; and another to control its maintenance by helping you to not get distracted.
Image credit: GettyThe ghost roads driving tropical deforestationNature Podcast2024-04-10 | In this episode: 00:46 Mapping ‘ghost roads’ in tropical forests Across the world, huge numbers of illegal roads have been cut into forests. However, due to their illicit nature, the exact numbers of these roads and their impacts on ecosystems is poorly understood. To address this, researchers have undertaken a huge mapping exercise across the tropical Asia-Pacific region. Their findings reveal over a million kilometres of roads that don’t appear on official maps, and that their construction is a key driver for deforestation.
10:44 Research Highlights How climate change fuelled a record-breaking hailstorm in Spain, and an unusual technique helps researchers detect a tiny starquake.
Research Highlight: Baseball-sized hail in Spain began with a heatwave at sea nature.com/articles/d41586-024-00966-0 Research Highlight: Smallest known starquakes are detected with a subtle shift of colour
13:02 Briefing Chat A clinical trial to test whether ‘mini livers’ can grow in a person’s lymph node, and the proteins that may determine left-handedness.
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Image credit: Paul Hilton/GreenpeaceAudio long read: Why are so many young people getting cancer? What the data sayNature Podcast2024-04-05 | Around the world, rates of cancers that typically affect older adults are increasing in those under 50 years old. Models based on global data predict that the number of early-onset cancer cases like these will increase by around 30% between 2019 and 2030.
The most likely contributors — such as rising rates of obesity and early-cancer screening — do not fully account for the increase. To try and understand the reasons behind this trend, many researchers are searching for answers buried in studies that tracked the lives and health of children born half a century ago.
Jahi Chikwendiu/The Washington Post/GettyPregnancys effect on biological age, polite-birds, and the carbon cost of home-grown vegNature Podcast2024-04-03 | In this episode:
00:35 Pregnancy advances your ‘biological’ age — but giving birth turns it back Growing a baby leads to changes in the distribution of certain chemical markers on a pregnant person’s DNA, but new research suggests that after giving birth, these changes can revert to an earlier state.
08:07 Bird gestures to say 'after you 'A Japanese tit (Parus minor) will flutter its wings to invite their mate to enter the nest first. Use of these sorts of gestures, more complex than simply pointing at an object of interest, were thought to be limited to great apes, suggesting that there are more non-vocal forms of communication to be found in the animal kingdom.
13:34 The carbon cost of home-grown veg Research have estimated that the carbon footprint of home-grown food and community gardens is six-times greater than conventional, commercial farms. This finding surprised the authors — keen home-growers themselves — who emphasize that their findings can be used to help make urban efforts (which have worthwhile social benefits) more carbon-efficient.
20:29 A look at next week's total eclipseOn 8th April, a total eclipse of the Sun is due to trace a path across North America. We look at the experiments taking place and what scientists are hoping to learn.How climate change is affecting global timekeepingNature Podcast2024-03-27 | 01:28 Inflammation’s role in memory How memories are stored is an ongoing question in neuroscience. Now researchers have found an inflammatory pathway that responds to DNA damage in neurons has a key role in the persistence of memories. How this pathway helps memories persist is unclear, but the researchers suggest that how the DNA damage is repaired may play a role. As inflammation in the brain is often associated with disease, the team were surprised by this finding, which they hope will help uncover ways to better preserve our memories, especially in the face of neurodegenerative disorders.
11:14 How melting ice is affecting global timekeeping Due to variations in the speed of Earth’s rotation, the length of a day is rarely exactly 24 hours. By calculating the strength of the different factors affecting this, a researcher has shown that while Earth’s rotation is overall speeding up, this effect is being tempered by the melting of the polar ice caps. As global time kept by atomic clocks occasionally has to be altered to match Earth’s rotation, human-induced climate change may delay plans to add a negative leap-second to ensure the two align.
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Image credit: GettyAI hears hidden X factor in zebra finch love songsNature Podcast2024-03-22 | This podcast has been corrected: in a previous version at 5:55 we stated that that the team's 200mm devices currently contain only a couple of magnetic tunnelling junctions, in fact they studied 500-1000 devices in this work.
In this episode: 00:48 How mysterious skyrmions could power next-generation computers Skyrmions are tiny whirlpools of magnetic spin that some researchers believe have useful properties that could unlock new kinds of computing. However getting skyrmions to perform useful computational tasks has been tricky. Now researchers have developed a method to create and manipulate skyrmions in a way that is compatible with existing computing technology, allowing them to read and write data at a fraction of the energy cost of conventional systems. The team think this shows that skyrmions could be a viable part of the next generation of computers.
07:51 Research Highlights How robotically-enhanced, live jellyfish could make ocean monitoring cheap and easy, and how collective saliva tests could be a cost-effective way of testing for a serious infant infection.
10:01 AI identifies X factor hidden within Zebra finch songs
Male songbirds often develop elaborate songs to demonstrate their fitness, but many birds only learn a single song and stick with it their entire lives. How female birds judge the fitness between these males has been a long-standing puzzle. Now, using an AI-based system a team has analysed the songs of male zebra finches and shown that some songs have a hidden factor that is imperceptible to humans. Although it’s not clear exactly what this factor is, songs containing it were shown to be harder to learn and more attractive to females. The researchers hope that this AI-based method will allow them to better understand what makes some birdsong more attractive than others.
20:04 Briefing Chat How H5N1 avian influenza is threatening penguins on Antarctica, and why farmed snake-meat could be a more environmentally-friendly way to produce protein for food.
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Image credit: Chris Ison/AlamyKiller whales have menopause. Now scientists think they know whyNature Podcast2024-03-14 | In this episode: 00:45 Making a map of the human heart The human heart consists of multiple, specialised structures that all work together to enable the organ to beat for a lifetime. But exactly which cells are present in each part of the heart has been difficult to ascertain. Now, a team has combined molecular techniques to create an atlas of the developing human heart at an individual cell level. Their atlas provides insights into how cell communities communicate and form different structures. They hope that this knowledge will ultimately help in the treatment of congenital heart conditions, often caused by irregular development of the heart.
08:37 Research Highlights Residue in ceramic vases suggests that ancient Mesoamerican peoples consumed tobacco as a liquid, and a wireless way to charge quantum batteries.
11:11 The evolution of menopause in toothed whales Menopause is a rare phenomenon, only known to occur in a few mammalian species. Several of these species are toothed whales, such as killer whales, beluga whales and narwhals. But why menopause evolved multiple times in toothed whales has been a long-standing research question. To answer it, a team examined the life history of whales with and without menopause and how this affected the number of offspring and ‘grandoffpsring’. Their results suggest that menopause allows older females to help younger generations in their families and improve their chances of survival.
18:03 Briefing Chat How the new generation of anti-obesity drugs could help people with HIV, and the study linking microplastics lodged in a key blood vessel with serious health issues.
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Image credit: Espen Bergersen/Nature Picture LibraryThese tiny fish combine electric pulses to probe the environmentNature Podcast2024-03-06 | In this episode: 00:48 Bumblebees can learn new tricks from each other One behaviour thought unique to humans is the ability to learn something from your predecessors that you couldn’t figure out on your own. However, researchers believe they have shown bumblebees are also capable of this ‘standing on the shoulders of giants’ approach to learning. Bees that were taught how to complete a puzzle too difficult to solve on their own, were able to share this knowledge with other bees, raising the possibility that this thought-to-be human trait could be widespread amongst animals.
19:28 The fish that collectively, electrically sense Many ocean-dwelling animals sense their environment using electric pulses, which can help them hunt and avoid predators. Now research shows that the tiny elephantnose fish can increase the range of this sense by combining its pulses with those of other elephantnose fish. This allows them to discriminate and determine the location of different objects at a much greater distance than a single fish is able to. This is the first time a collective electric sense has been seen in animals, which could provide an ‘early-warning system', allowing a group to avoid predators from a greater distance.
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Image credit: ShutterstockCould this one-time ‘epigenetic’ treatment control cholesterol?Nature Podcast2024-02-28 | In this episode: 00:49 What caused the Universe to become fully transparent? Around 13 billion years ago, the Universe was filled with a dense ‘fog’ of neutral hydrogen that blocked certain wavelengths of light. This fog was lifted when the hydrogen was hit by radiation in a process known as reionisation, but the source of this radiation has been debated. Now, researchers have used the JWST to peer deep into the Universe’s past and found that charged particles pouring out from dwarf galaxies appear to be the the main driver for reionization. This finding could help researchers understand how some of the structures we now see in the Universe were formed.
08:46 Research Highlights Ancient inscriptions could be the earliest example of the language that became Basque, and how researchers etched a groove… onto soap film.
To combat high cholesterol, many people take statins, but because these drugs have to be taken every day researchers have been searching for alternatives. Controlling cholesterol by editing the epigenome has shown promise in lab-grown cells, but its efficacy in animals was unclear. Now, researchers have shown the approach can work in mice, and have used it to silence a gene linked to high cholesterol for a year. The mice show markedly lowered cholesterol, a result the team hope could pave the way for epigenetic therapeutics for humans.
18:52 The gene mutation explaining why humans don’t have tails Why don’t humans and other apes have a tail? It was assumed that a change must have happened in our genomes around 25 million years ago that resulted in the loss of this flexible appendage. Now researchers believe they have pinned down a good candidate for what caused this: an insertion into a particular gene known as TBXT. The team showed the key role this gene plays by engineering mice genomes to contain a similar change, leading to animals that were tail-less. This finding could help paint a picture of the important genetic mutations that led to the evolution of humans and other apes.
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