Google DeepMind
Unreasonably Effective AI with Demis Hassabis
updated
Read our case study blog: deepmind.com/blog/optimising-computer-systems-with-more-generalised-ai-tools
Enter Flamingo, our powerful visual language model generating metadata descriptions for hundreds of millions of videos.
Every day, DeepMind scholars like Vitor are making their mark in artificial intelligence. In the AI by you series, they express what artificial intelligence means to them, in their own words. Learn what drives them and how they'll use artificial intelligence technology to help build a better future for everyone.
Watch the full series here: youtube.com/playlist?list=PLqYmG7hTraZDoNy8TLPk-uB4FyaZ23xon
And visit deepmind.com/scholarships to learn more.
Every day, DeepMind scholars like Arnol are making their mark in artificial intelligence. In the AI by you series, they express what artificial intelligence means to them, in their own words. Learn what drives them and how they'll use artificial intelligence technology to help build a better future for everyone.
Watch the full series here: youtube.com/playlist?list=PLqYmG7hTraZDoNy8TLPk-uB4FyaZ23xon
And visit deepmind.com/scholarships to learn more.
Every day, DeepMind scholars like Weronika are making their mark in artificial intelligence. In the AI by you series, they express what artificial intelligence means to them, in their own words. Learn what drives them and how they'll use artificial intelligence technology to help build a better future for everyone.
Watch the full series here: youtube.com/playlist?list=PLqYmG7hTraZDoNy8TLPk-uB4FyaZ23xon
And visit deepmind.com/scholarships to learn more.
Every day, DeepMind scholars like Sneha are making their mark in artificial intelligence. In the AI by you series, they express what artificial intelligence means to them, in their own words. Learn what drives them and how they'll use artificial intelligence technology to help build a better future for everyone.
Watch the full series here: youtube.com/playlist?list=PLqYmG7hTraZDoNy8TLPk-uB4FyaZ23xon
Visit deepmind.com/scholarships to learn more.
Every day, DeepMind scholars like Julia are making their mark in artificial intelligence. In the AI by you series, they express what artificial intelligence means to them, in their own words. Learn what drives them and how they'll use artificial intelligence technology to help build a better future for everyone.
Watch the full series here: youtube.com/playlist?list=PLqYmG7hTraZDoNy8TLPk-uB4FyaZ23xon
And visit deepmind.com/scholarships to learn more.
We need a stronger, more inclusive AI community. A community that brings diverse values, concerns, and hopes to the table. Only then, can the whole of humanity truly benefit from this technology. AI for everyone needs AI by you.
We established the DeepMind scholarship programme in 2017 to help build a stronger and more inclusive AI community, who can bring a wider range of experiences to the fields of AI and computer science. The scholarships provide financial support to students from underrepresented groups seeking to graduate studies in AI-related and adjacent fields. Scholars are also offered support from a DeepMind mentor, and have opportunities to attend leading AI academic conferences and DeepMind events.
Over the last five years, the scholarship programme has expanded internationally, and now supports scholars in many more countries currently underrepresented in AI – including Bulgaria, Colombia, Greece, Poland, Romania, South Africa, and Turkey, as well as the UK, USA, Canada, and France.
Watch our scholars stories film series here: youtube.com/playlist?list=PLqYmG7hTraZDoNy8TLPk-uB4FyaZ23xon
And visit deepmind.com/scholarships to learn more.
But the evidence was not clear cut. The burned eggshells seemed far too thin to come from such a large bird. Were they not from something much smaller, more the size of a large turkey?
To determine whether Genyornis became extinct through human intervention, scientists needed to prove that the burnt eggshells were indeed from Genyornis. But that led to a new problem. The DNA in these eggshells was never going to survive 50,000 years in the hot sands of the Australian desert. So, the researchers turned to proteins and artificial intelligence to help fill in the gaps.
It took a genuinely multidisciplinary team including specialists in palaeoproteomics, bird genetics, archaeology and more to crack the eggshell code and answer the question of what led to the demise of the thunderbird.
Read the full paper by Beatrice, Josefin, Matthew and colleagues in Proceedings of the National Academy of Sciences.
To make this possible, we bring together scientists, designers, engineers, ethicists, and more, to research and build safe artificial intelligence systems that can help transform society for the better.
By combining creative thinking with our dedicated, scientific approach, we’re unlocking new ways of solving complex problems and working to develop a more general and capable problem-solving system, known as artificial general intelligence (AGI). Guided by safety and ethics, this invention could help society find answers to some of the most important challenges facing society today.
We regularly partner with academia and nonprofit organisations, and our technologies are used across Google devices by millions of people every day. From solving a 50-year-old grand challenge in biology with AlphaFold and synthesising voices with WaveNet, to mastering complex games with AlphaZero and preserving wildlife in the Serengeti, our novel advances make a positive and lasting impact.
Incredible ideas thrive when diverse people join together. With headquarters in London and research labs in Paris, New York, Montreal, Edmonton, and Mountain View, CA, we’re always looking for great people from all walks of life to join our mission.
Learn more at deepmind.com/about and apply for open roles at deepmind.com/careers.
#LifeAtDeepMind #artificialintelligence #AGI #socialimpact
The world produces around 400m tonnes of plastic waste each year. Much of it ends up in landfill; a significant portion is polluting the world’s oceans. Conventional plastic recycling only degrades the material – in fact, most plastic items never fully disappear.
John McGeehan, Rosie Graham, and their colleagues at the Centre for Enzyme Innovation at the University of Portsmouth, are developing a different solution: a fully circular plastic economy, using enzymes to break plastic polymers down so they can be 100% recycled back to their initial state – or even upcycling degraded material back to the quality of virgin plastic.
As part of Unfolded, a series documenting the scientists using AlphaFold, we met John and Rosie at their labs in Portsmouth to find out how a chance email has accelerated this work.
Find more Unfolded stories at unfolded.deepmind.com
Marcelo Sousa and Megan Mitchell at the University of Colorado Boulder are looking at a different approach: targeting the resistance mechanism itself, controlled in this case with enzymes.
As part of Unfolded, a series meeting the scientists using AlphaFold, Marcelo and Megan explain how they solved the structure of one such enzyme - a challenge that a decade of experimentation couldn’t complete - in minutes.
Find more Unfolded stories at unfolded.deepmind.com
EMBL-EBI champions open data in the life sciences, with data sets spanning genomics, proteins, small molecules, ontologies and more. They were a natural partner for DeepMind to host the AlphaFold Protein Structure Database, now making over 200m protein structure predictions freely available to scientists globally.
As part of Unfolded, a series meeting the scientists using AlphaFold, we travelled to EMBL-EBI’s home at the Wellcome Genome Campus in Hinxton, UK, to meet Janet and Mihaly.
Find more Unfolded stories at unfolded.deepmind.com
To make this possible, we bring together scientists, designers, engineers, ethicists, and more, to research and build safe artificial intelligence systems that can help transform society for the better.
By combining creative thinking with our dedicated, scientific approach, we’re unlocking new ways of solving complex problems and working to develop a more general and capable problem-solving system, known as artificial general intelligence (AGI). Guided by safety and ethics, this invention could help society find answers to some of the most important challenges facing society today.
We regularly partner with academia and nonprofit organisations, and our technologies are used across Google devices by millions of people every day. From solving a 50-year-old grand challenge in biology with AlphaFold and synthesising voices with WaveNet, to mastering complex games with AlphaZero and preserving wildlife in the Serengeti, our novel advances make a positive and lasting impact.
Incredible ideas thrive when diverse people join together. With headquarters in London and research labs in Paris, New York, Montreal, and Mountain View, CA, we’re always looking for great people from all walks of life to join our mission.
Learn more at deepmind.com/about and apply for open roles at deepmind.com/careers.
#LifeAtDeepMind #artificialintelligence #AGI #socialimpact
In October 2015, AlphaGo became the first computer program ever to beat a professional Go player by winning 5-0 against the reigning 3-times European Champion Fan Hui (2-dan pro). That work was featured in a front cover article in the science journal Nature in January 2016.
In October 2015, AlphaGo became the first computer program ever to beat a professional Go player by winning 5-0 against the reigning 3-times European Champion Fan Hui (2-dan pro). That work was featured in a front cover article in the science journal Nature in January 2016.
In October 2015, AlphaGo became the first computer program ever to beat a professional Go player by winning 5-0 against the reigning 3-times European Champion Fan Hui (2-dan pro). That work was featured in a front cover article in the science journal Nature in January 2016.
In October 2015, AlphaGo became the first computer program ever to beat a professional Go player by winning 5-0 against the reigning 3-times European Champion Fan Hui (2-dan pro). That work was featured in a front cover article in the science journal Nature in January 2016.
In October 2015, AlphaGo became the first computer program ever to beat a professional Go player by winning 5-0 against the reigning 3-times European Champion Fan Hui (2-dan pro). That work was featured in a front cover article in the science journal Nature in January 2016.
For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com.
Interviewee: Deepmind co-founder and CEO, Demis Hassabis
Credits
Presenter: Hannah Fry
Series Producer: Dan Hardoon
Production support: Jill Achineku
Sounds design: Emma Barnaby
Music composition: Eleni Shaw
Sound Engineer: Nigel Appleton
Editor: David Prest
Commissioned by DeepMind
Thank you to everyone who made this season possible!
Further reading:
DeepMind, The Podcast: deepmind.com/blog/article/welcome-to-the-deepmind-podcast
DeepMind’s Demis Hassabis on its breakthrough scientific discoveries, WIRED: youtube.com/watch?v=2WRow9FqUbw
Riemann hypothesis, Wikipedia: en.wikipedia.org/wiki/Riemann_hypothesis
Using AI to accelerate scientific discovery by Demis Hassabis, Kendrew Lecture 2021: youtube.com/watch?v=sm-VkgVX-2o
Protein Folding & the Next Technological Revolution by Demis Hassabis, Bloomberg: youtube.com/watch?v=vhd4ENh5ON4
The Algorithm, MIT Technology Review: forms.technologyreview.com/newsletters/ai-the-algorithm
Machine learning resources, The Royal Society: royalsociety.org/topics-policy/education-skills/teacher-resources-and-opportunities/resources-for-teachers/resources-machine-learning
How to get empowered, not overpowered, by AI, TED: youtube.com/watch?v=2LRwvU6gEbA
YouTube addition:
Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL
Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app:
Apple Podcasts: http://dpmd.ai/2Rzlmcu
Google Podcasts: http://dpmd.ai/3geDjp5
Spotify: http://dpmd.ai/3w29cb4
Pocket Casts: https://pca.st/30m1
Demis Hassabis, co-founder and CEO, DeepMind
At The Francis Crick Institute in King's Cross, London
Abstract:
The past decade has seen incredible advances in the field of Artificial Intelligence (AI). DeepMind has been in the vanguard of many of these big breakthroughs, pioneering the development of self-learning systems like AlphaGo, the first program to beat the world champion at the complex game of Go. Games have proven to be a great training ground for developing and testing AI algorithms, but the aim at DeepMind has always been to build general learning systems ultimately capable of solving important problems in the real world. Excitingly, I believe we are on the cusp of a new era in science with AI poised to be a powerful tool for accelerating scientific discovery itself. We recently demonstrated this potential with our AlphaFold system, a solution to the 50-year grand challenge of protein structure prediction, culminating in the release of the most accurate and complete picture of the human proteome.
The speaker:
Demis Hassabis is the Founder and CEO of DeepMind, the world's leading AI research company that aims to solve intelligence to advance science and benefit humanity
In 2016, DeepMind developed AlphaGo, the first program to beat a world champion at the complex game of Go. In 2020, its Alphafold program was heralded as a solution to the 50-year grand challenge of protein structure prediction and in 2021, DeepMind launched the AlphaFold Protein Structure Database, which offers the most complete and accurate picture of the human proteome to date.
A chess prodigy, Demis reached master standard aged 13, and went on to program the multi-million selling simulation game Theme Park aged 17. After graduating from Cambridge University in computer science, he founded pioneering videogames company Elixir Studios, and completed a PhD in cognitive neuroscience at University College London. Science listed his neuroscience research on imagination as one of 2007’s top ten breakthroughs, and in 2021, AlphaFold2 was selected as the Breakthrough of the Year.
He is a Fellow of the Royal Society and the Royal Academy of Engineering. In 2017 he featured in the Time 100 list of most influential people, and in 2018 he was awarded a CBE for services to science and technology.
For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com.
Interviewees: DeepMind’s Sasha Brown, William Isaac, Shakir Mohamed, Kevin Mckee & Obum Ekeke
Credits
Presenter: Hannah Fry
Series Producer: Dan Hardoon
Production support: Jill Achineku
Sounds design: Emma Barnaby
Music composition: Eleni Shaw
Sound Engineer: Nigel Appleton
Editor: David Prest
Commissioned by DeepMind
Thank you to everyone who made this season possible!
Further reading:
What a machine learning tool that turns Obama white can (and can’t) tell us about AI bias, The Verge: theverge.com/21298762/face-depixelizer-ai-machine-learning-tool-pulse-stylegan-obama-bias
Tuskegee Syphilis Study, Wikipedia: en.wikipedia.org/wiki/Tuskegee_Syphilis_Study
Ethics & Society, DeepMind: deepmind.com/about/ethics-and-society
Row over AI that 'identifies gay faces', BBC: bbc.co.uk/news/technology-41188560
The Trevor Project: thetrevorproject.org
AI takes root, helping farmers identify diseased plants, Google: https://www.blog.google/technology/ai/ai-takes-root-helping-farmers-identity-diseased-plants/
How Can You Use Technology to Support a Culture of Inclusion and Diversity?, myHRfuture: myhrfuture.com/blog/2019/7/16/how-can-you-use-technology-to-support-a-culture-of-inclusion-and-diversity
Scholarships at DeepMind: deepmind.com/scholarships
AI, Ain’t I a Woman? Joy Buolamwini, YouTube: youtube.com/watch?v=QxuyfWoVV98
How to be Human in the Age of the Machine, Hannah Fry: royalsociety.org/grants-schemes-awards/book-prizes/science-book-prize/2018/hello-world
Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL
Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app:
Apple Podcasts: http://dpmd.ai/2Rzlmcu
Google Podcasts: http://dpmd.ai/3geDjp5
Spotify: http://dpmd.ai/3w29cb4
Pocket Casts: https://pca.st/30m1
For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com.
Interviewees: DeepMind’s Demis Hassabis, Raia Hadsell, Karl Tuyls, Zach Gleicher & Jackson Broshear; Niall Robinson of the UK Met Office
Credits
Presenter: Hannah Fry
Series Producer: Dan Hardoon
Production support: Jill Achineku
Sounds design: Emma Barnaby
Music composition: Eleni Shaw
Sound Engineer: Nigel Appleton
Editor: David Prest
Commissioned by DeepMind
Thank you to everyone who made this season possible!
Further reading:
A generative model for raw audio, DeepMind: deepmind.com/blog/article/wavenet-generative-model-raw-audio
WaveNet case study, DeepMind: deepmind.com/research/case-studies/wavenet
Using WaveNet technology to reunite speech-impaired users with their original voices, DeepMind:| deepmind.com/blog/article/Using-WaveNet-technology-to-reunite-speech-impaired-users-with-their-original-voices
Project Euphonia, Google Research: https://sites.research.google/euphonia/about/
Nowcasting the next hour of rain, DeepMind: deepmind.com/blog/article/nowcasting
Now DeepMind is using AI to transform football, WIRED: wired.co.uk/article/deepmind-football-liverpool-ai
Advancing sports analytics through AI, DeepMind: deepmind.com/blog/article/advancing-sports-analytics-through-ai
MetOffice, BBC: metoffice.gov.uk
The village ‘washed on to the map’, BBC: bbc.co.uk/news/uk-england-cornwall-28523053
Michael Fish got the storm of 1987 wrong, Sky News: news.sky.com/story/michael-fish-got-the-storm-of-1987-wrong-but-modern-supercomputers-may-have-missed-it-too-11076659#:~:text=In%20a%20lunchtime%20broadcast%20on,%2C%22%20he%20confidently%20told%20viewers.
Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL
Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app:
Apple Podcasts: http://dpmd.ai/2Rzlmcu
Google Podcasts: http://dpmd.ai/3geDjp5
Spotify: http://dpmd.ai/3w29cb4
Pocket Casts: https://pca.st/30m1
For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com.
Interviewees: DeepMind’s Demis Hassabis, Pushmeet Kohli & Sarah Jane Dunn; Meredith Palmer of the Princeton University
Credits
Presenter: Hannah Fry
Series Producer: Dan Hardoon
Production support: Jill Achineku
Sounds design: Emma Barnaby
Music composition: Eleni Shaw
Sound Engineer: Nigel Appleton
Editor: David Prest
Commissioned by DeepMind
Thank you to everyone who made this season possible!
Further reading:
Using AI for scientific discovery, DeepMind: deepmind.com/blog/article/AlphaFold-Using-AI-for-scientific-discovery
DeepMind’s Demis Hassabis on its breakthrough scientific discoveries, WIRED: youtube.com/watch?v=2WRow9FqUbw
The AI revolution in scientific research, The Royal Society: royalsociety.org/-/media/policy/projects/ai-and-society/AI-revolution-in-science.pdf
DOE Explains...Tokamaks, Office of Science: energy.gov/science/doe-explainstokamaks
How AI Accidentally Learned Ecology by Playing StarCraft, Discover: discovermagazine.com/technology/how-ai-accidentally-learned-ecology-by-playing-starcraft
Google AI can identify wildlife from trap-camera footage, VentureBeat:
venturebeat.com/2019/12/17/googles-ai-can-identify-wildlife-from-trap-camera-footage-with-up-to-98-6-accuracy
Snapshot Serengeti, Zooniverse:
zooniverse.org/projects/zooniverse/snapshot-serengeti
The Human Genome Project, National Human Genome Research Institute: genome.gov/human-genome-project
Exploring the beauty of pure mathematics in novel ways, DeepMind: deepmind.com/blog/article/exploring-the-beauty-of-pure-mathematics-in-novel-ways
Predicting gene expression with AI, DeepMind: deepmind.com/blog/article/enformer
Using machine learning to accelerate ecological research, DeepMind: deepmind.com/blog/article/using-machine-learning-to-accelerate-ecological-research
Accelerating fusion science through learned plasma control, DeepMind: deepmind.com/blog/article/Accelerating-fusion-science-through-learned-plasma-control
Simulating matter on the quantum scale with AI, DeepMind: deepmind.com/blog/article/Simulating-matter-on-the-quantum-scale-with-AI
How AI is helping the natural sciences, Nature: nature.com/articles/d41586-021-02762-6
Inside DeepMind's epic mission to solve science's trickiest problem, WIRED: wired.co.uk/article/deepmind-protein-folding
How Artificial Intelligence Is Changing Science, Quanta: quantamagazine.org/how-artificial-intelligence-is-changing-science-20190311
Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL
Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app:
Apple Podcasts: http://dpmd.ai/2Rzlmcu
Google Podcasts: http://dpmd.ai/3geDjp5
Spotify: http://dpmd.ai/3w29cb4
Pocket Casts: https://pca.st/30m1
For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com.
Interviewees: DeepMind’s Shane Legg, Doina Precup, Dave Silver & Jackson Broshear
Credits
Presenter: Hannah Fry
Series Producer: Dan Hardoon
Production support: Jill Achineku
Sounds design: Emma Barnaby
Music composition: Eleni Shaw
Sound Engineer: Nigel Appleton
Editor: David Prest
Commissioned by DeepMind
Thank you to everyone who made this season possible!
Further reading:
Real-world challenges for AGI, DeepMind: deepmind.com/blog/article/real-world-challenges-for-agi
An executive primer on artificial general intelligence, McKinsey: mckinsey.com/business-functions/operations/our-insights/an-executive-primer-on-artificial-general-intelligence
Mastering Go, chess, shogi and Atari without rules, DeepMind: deepmind.com/blog/article/muzero-mastering-go-chess-shogi-and-atari-without-rules
What is AGI?, Medium: medium.com/intuitionmachine/what-is-agi-99cdb671c88e
A Definition of Machine Intelligence by Shane Legg, arXiv: arxiv.org/abs/0712.3329
Reward is enough by David Silver, ScienceDirect: sciencedirect.com/science/article/pii/S0004370221000862
Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL
Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app:
Apple Podcasts: http://dpmd.ai/2Rzlmcu
Google Podcasts: http://dpmd.ai/3geDjp5
Spotify: http://dpmd.ai/3w29cb4
Pocket Casts: https://pca.st/30m1
For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com.
Interviewees: DeepMind’s Raia Hadsell, Viorica Patraucean, Jan Humplik, Akhil Raju & Doina Precup
Credits
Presenter: Hannah Fry
Series Producer: Dan Hardoon
Production support: Jill Achineku
Sounds design: Emma Barnaby
Music composition: Eleni Shaw
Sound Engineer: Nigel Appleton
Editor: David Prest
Commissioned by DeepMind
Thank you to everyone who made this season possible!
Further reading:
Stacking our way to more general robots, DeepMind: deepmind.com/blog/article/stacking-our-way-to-more-general-robots
Researchers Propose Physical AI As Key To Lifelike Robots, Forbes: forbes.com/sites/simonchandler/2020/11/11/researchers-propose-physical-ai-as-key-to-lifelike-robots
The robots going where no human can, BBC: bbc.co.uk/news/av/technology-41584738
The Robot Assault On Fukushima, WIRED: wired.com/story/fukushima-robot-cleanup
Leaps, Bounds, and Backflips, Boston Dynamics: http://blog.bostondynamics.com/atlas-leaps-bounds-and-backflips
Now DeepMind is using AI to transform football, WIRED: wired.co.uk/article/deepmind-football-liverpool-ai
Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL
Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app:
Apple Podcasts: http://dpmd.ai/2Rzlmcu
Google Podcasts: http://dpmd.ai/3geDjp5
Spotify: http://dpmd.ai/3w29cb4
Pocket Casts: https://pca.st/30m1
For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com.
Interviewees: DeepMind’s Thore Graepel, Kevin Mckee, Doina Precup & Laura Weidinger
Credits
Presenter: Hannah Fry
Series Producer: Dan Hardoon
Production support: Jill Achineku
Sounds design: Emma Barnaby
Music composition: Eleni Shaw
Sound Engineer: Nigel Appleton
Editor: David Prest
Commissioned by DeepMind
Thank you to everyone who made this season possible!
Further reading:
Machines must learn to find common ground, Nature: nature.com/articles/d41586-021-01170-0
Introduction to Reinforcement Learning, DeepMind: youtube.com/watch?v=2pWv7GOvuf0
B.F. Skinner, Wikipedia: en.wikipedia.org/wiki/B._F._Skinner
The Tragedy of the Commons, Wikipedia: en.wikipedia.org/wiki/Tragedy_of_the_commons
Staving Off The Ultimate Tragedy Of The Commons, Forbes: forbes.com/sites/georgebradt/2021/11/02/staving-off-the-ultimate-tragedy-of-the-commons-by-making-better-complex-decisions-cooperatively-in-glasgow
Understanding Agent Cooperation, DeepMind: deepmind.com/blog/article/understanding-agent-cooperation
The emergence of complex cooperative agents, DeepMind: deepmind.com/blog/article/capture-the-flag-science
Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL
Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app:
Apple Podcasts: http://dpmd.ai/2Rzlmcu
Google Podcasts: http://dpmd.ai/3geDjp5
Spotify: http://dpmd.ai/3w29cb4
Pocket Casts: https://pca.st/30m1
For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com.
Interviewees: DeepMind’s Demis Hassabis, John Jumper, Kathryn Tunyasunakool and Sasha Brown; Charles Mowbray and Monique Wasuna of the Drugs for Neglected Diseases initiative (DNDi]) & John McGeehan of the Centre for Enzyme Innovation at the University of Portsmouth
Credits
Presenter: Hannah Fry
Series Producer: Dan Hardoon
Production support: Jill Achineku
Sounds design: Emma Barnaby
Music composition: Eleni Shaw
Sound Engineer: Nigel Appleton
Editor: David Prest
Commissioned by DeepMind
Thank you to everyone who made this season possible!
Further reading:
AlphaFold blog, DeepMind: deepmind.com/blog/article/alphafold-a-solution-to-a-50-year-old-grand-challenge-in-biology
AlphaFold case study, DeepMind: deepmind.com/research/case-studies/alphafold
It will change everything, Nature: nature.com/articles/d41586-020-03348-4
AlphaFold Is The Most Important Achievement In AI—Ever, Forbes: forbes.com/sites/robtoews/2021/10/03/alphafold-is-the-most-important-achievement-in-ai-ever/?sh=359278426e0a
Bacteria found to eat PET plastics, NewScientist: newscientist.com/article/2080279-bacteria-found-to-eat-pet-plastics-could-help-do-the-recycling
Protein Structure Prediction Center: predictioncenter.org
An interview with Professor John McGeehan, BBSRC: bbsrc.ukri.org/news/features/enzyme-science/an-interview-with-professor-john-mcgeehan
John McGeehan profile, University of Portsmouth: researchportal.port.ac.uk/en/persons/john-mcgeehan
Drugs for Neglected Diseases initiative (DNDi): dndi.org
A doctor’s dream, DNDi: youtube.com/watch?v=Tk31iucWYdE
The Curious Cases of Rutherford and Fry, BBC: bbc.co.uk/programmes/b07dx75g/episodes/downloads
Hannah Fry: hannahfry.co.uk
Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL
Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app:
Apple Podcasts: http://dpmd.ai/2Rzlmcu
Google Podcasts: http://dpmd.ai/3geDjp5
Spotify: http://dpmd.ai/3w29cb4
Pocket Casts: https://pca.st/30m1
For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com.
Interviewees: DeepMind’s Geoffrey Irving, Chris Dyer, Angeliki Lazaridou, Lisa-Anne Hendriks & Laura Weidinger
Credits
Presenter: Hannah Fry
Series Producer: Dan Hardoon
Production support: Jill Achineku
Sounds design: Emma Barnaby
Music composition: Eleni Shaw
Sound Engineer: Nigel Appleton
Editor: David Prest
Commissioned by DeepMind
Thank you to everyone who made this season possible!
Further reading:
GPT-3 Powers the Next Generation of Apps, OpenAI: openai.com/blog/gpt-3-apps
https://web.stanford.edu/class/linguist238/p36-weizenabaum.pdf
Never Mind the Computer 1983 about the ELIZA program, BBC: bbc.co.uk/programmes/p023kpf8
How Large Language Models Will Transform Science, Society, and AI, Stanford University: https://hai.stanford.edu/news/how-large-language-models-will-transform-science-society-and-ai
Challenges in Detoxifying Language Models, DeepMind: deepmind.com/research/publications/2021/Challenges-in-Detoxifying-Language-Models
Extending Machine Language Models toward Human-Level Language Understanding, DeepMind: deepmind.com/research/publications/2020/Extending-Machine-Language-Models-toward-Human-Level-Language-Understanding
Language modelling at scale, DeepMind: deepmind.com/blog/article/language-modelling-at-scale
Artificial general intelligence, Technology Review: technologyreview.com/2020/10/15/1010461/artificial-general-intelligence-robots-ai-agi-deepmind-google-openai
A Definition of Machine Intelligence by Shane Legg, arXiv: arxiv.org/abs/0712.3329
Stuart Russell - Living With Artificial Intelligence, BBC: bbc.co.uk/programmes/m001216k/episodes/player
Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL
Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app:
Apple Podcasts: http://dpmd.ai/2Rzlmcu
Google Podcasts: http://dpmd.ai/3geDjp5
Spotify: http://dpmd.ai/3w29cb4
Pocket Casts: https://pca.st/30m1
Recorded over six months and featuring over 30 original interviews, including DeepMind co-founders Demis Hassabis and Shane Legg, the podcast gives listeners exclusive access to the brilliant people building the technology of the future. Throughout nine original episodes, Hannah discovers how DeepMind is using AI to advance science in critical areas, like solving a 50-year-old grand challenge in biology and developing nuclear fusion.
Listeners hear stories of teaching robots to walk at home during lockdown, as well as using AI to forecast weather, help people regain their voices, and enhance game strategies with Liverpool Football Club. Hannah also takes an in-depth look at the challenges and potential of building artificial general intelligence (AGI) and explores what it takes to ensure AI is built to benefit society.
“I hope this series gives people a better understanding of AI and a feeling for just how exhilarating an endeavour it is.” – Demis Hassabis, CEO and Co-Founder of DeepMind
For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com.
Credits
Presenter: Hannah Fry
Series Producer: Dan Hardoon
Production support: Jill Achineku
Sounds design: Emma Barnaby
Music composition: Eleni Shaw
Sound Engineer: Nigel Appleton
Editor: David Prest
Commissioned by DeepMind
Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL
Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app:
Apple Podcasts: http://dpmd.ai/2Rzlmcu
Google Podcasts: http://dpmd.ai/3geDjp5
Spotify: http://dpmd.ai/3w29cb4
Pocket Casts: https://pca.st/30m1
Slides: dpmd.ai/introslides
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/explorationcontrol
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/MDPs
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/dynamicprogramming
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/modelfreeprediction
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/modelfreecontrol
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/functionapproximation
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/planningmodels
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/policygradient
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/approximatedynamic
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/offpolicy
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/deeprl1
Full video lecture series: dpmd.ai/DeepMindxUCL21
Slides: dpmd.ai/deeprl2
Full video lecture series: dpmd.ai/DeepMindxUCL21
Further reading blog: deepmind.com/blog/article/generally-capable-agents-emerge-from-open-ended-play
Paper: deepmind.com/research/publications/open-ended-learning-leads-to-generally-capable-agents
Timestamps of Results:
00:00 Intro
00:24 Tag Fiesta
01:23 King of the Hill
02:18 Hide and Seek
04:22 Capture the Flag
06:57 Catch 'em All
07:53 Choose Wisely
08:47 Nowhere to Hide
09:33 Stop Roll
10:43 Near not Near
11:53 See not See
12:42 Build Ramp
14:26 Outro
Date: 09/12/20
Slides: bit.ly/3pQB0vl
Find out more:
deepmind.com/alphafold
Protein references:
TBP = To be published
1BYI: Sandalova, T., et al. (1999) Structure of dethiobiotin synthetase at 0.97 A resolution. Acta Crystallographica Section D 55: 610-624.
3NPD: Das, D. et al. (2014) Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family. Proteins 82: 1086-1092.
5AOZ: Bule, P., et al. Structural Characterization of the Third Cohesin from Ruminococcus Flavefaciens Scaffoldin Protein, Scab. (TBP)
5ERE: Joachimiak, A. A novel extracellular ligand receptor. (TBP)
5L8E: Dharadhar, S., et al. (2016) A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme. Journal of Structural Biology 196: 437-447.
5M20: Liauw, P., et al. Structure of Thermosynechococcus elongatus Psb32 fused to sfGFP. (TBP)
5W9F: Buchko, G.W., et al. (2018) Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides. Protein Science 27: 1611-1623.
6BTC: Mir-Sanchis, I., et al. (2018) Crystal Structure of an Unusual Single-Stranded DNA-Binding Protein Encoded by Staphylococcal Cassette Chromosome Elements. Structure 26: 1144.
6CL6: Buth, S.A., et al. (2018) Structure and Analysis of R1 and R2 Pyocin Receptor-Binding Fibers. Viruses 10.
6CP9: Gucinski, G.C., et al. (2019) Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins. Structure 27: 1660.
6CVZ: Loppnau, P., et al. Crystal structure of the WD40-repeat of RFWD3. (TBP)
6D2V: Clinger, J.A., et al. Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC. (TBP)
6E4B: Tan, K., et al. The crystal structure of a putative alpha-ribazole-5'-P phosphatase from Escherichia coli str. K-12 substr. MG1655 (CASP target). (TBP)
6EK4: Brauning, B., et al. (2018) Structure and mechanism of the two-component alpha-helical pore-forming toxin YaxAB. Nature Communications 9: 1806-1806.
6F45: Dunne, M., et al. (2018) Salmonella Phage S16 Tail Fiber Adhesin Features a Rare Polyglycine Rich Domain for Host Recognition. Structure 26: 1573-1582.e4.
6M9T: Audet, M., et al. (2019) Crystal structure of misoprostol bound to the labor inducer prostaglandin E2receptor. Nature Chemical Biology 15: 11-17.
6MSP: Koepnick, B., et al. (2019) De novo protein design by citizen scientists. Nature 570: 390-394.
6N64: Birkinshaw, R.W., et al. Structure of SMCHD1 hinge domain. (TBP)
6N9Y: Kerviel, A., et al. (2019) Atomic structure of the translation regulatory protein NS1 of bluetongue virus. Nature Microbiology 4: 837-845.
6ORI: Spiegelman, L., et al. Enterococcal surface protein, partial N-terminal region (CASP target). (TBP)
6PX4: Krieger, I.V., et al. (2020) The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition. Journal of Molecular Biology 432: 4623-4636.
6QVM: Osipov, E.M., et al. Crystal structure of native O-glycosylated multiheme cytochrome cf with S-layer binding domain. (TBP)
6T1Z: Debruycker, V., et al. (2020) An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity. Nature Structural & Molecular Biology 27: 829-835.
6TRI: Rasmussen, K.K., et al. (2020) Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage. PNAS 117: 20576-20585.
6U7L: Minasov, G., et al. 2.75 Angstrom Crystal Structure of Galactarate Dehydratase from Escherichia coli. (TBP)
6UBL: Kosgei, A.J., et al. Structure of DynF from the Dynemicin Biosynthesis Pathway of Micromonospora chersina. (TBP)
6UK5: Alvarado, S.K., et al. Structure of SAM bound CalS10, an amino pentose methyltransferase from Micromonospora echinaspora involved in calicheamicin biosynthesis. (TBP)
6VR4: Leiman, P.G., et al. Virion-packaged DNA-dependent RNA polymerase of crAss-like phage phi14:2 (CASP target). (TBP)
6X6O: Shi, K., et al. (2020) Crystal structure of bacteriophage T4 Spackle as determined by native SAD phasing. Acta Crystallographica Section D 76: 899-904.
6XBD: Coudray, N., et al. Structure of MlaFEDB lipid transporter reveals an ABC exporter fold and two bound phospholipids. (TBP)
6YA2: Bahat, Y., et al. First structure of a glycoprotein from enveloped plant virus. (TBP)
6YFN: Rumnieks, J., et al. Expansion of the structural diversity of single-stranded RNA bacteriophages. (TBP)
6YJ1: Sobieraj, A., et al. (CASP target) Crystal structure of the M23 peptidase domain of Staphylococcal phage 2638A endolysin. (TBP)
7JTL: Flower, T.G., et al. (2020) Structure of SARS-CoV-2 ORF8, a rapidly evolving coronavirus protein implicated in immune evasion. Biorxiv.
These tiny molecular machines underpin every biological process in every living thing and each one has a unique 3D shape that determines how it works and what it does.
But figuring out the exact structure of a protein is an expensive and often time-consuming process, meaning we only know the exact 3D structure of a tiny fraction of the 200m proteins known to science.
Being able to accurately predict the shape of proteins could accelerate research in every field of biology. That could lead to important breakthroughs like finding new medicines or finding proteins and enzymes that break down industrial and plastic waste or efficiently capture carbon from the atmosphere.
Join Kathryn as she explains what protein folding is, why it's important and how our Artificial Intelligence system AlphaFold offers a solution to this grand scientific challenge.
Find out more:
deepmind.com/alphafold
deepmind.com/scholarships
Download the slides here:
storage.googleapis.com/deepmind-media/UCLxDeepMind_2020/L12%20-%20UCLxDeepMind%20DL2020.pdf
Find out more about how DeepMind increases access to science here:
deepmind.com/about#access_to_science
Speaker Bios:
Chongli Qin is a research scientist at DeepMind, her primary interest is in building safer, more reliable and more trustworthy machine learning algorithms. Over the past several years, she has contributed in developing algorithms to make neural networks more robust to noise. Key parts of her research focuses on functional analysis: properties of neural network that can naturally enhance robustness. She has also contributed in building mathematical frameworks to verify/guarantee that certain properties hold for neural networks. Prior to DeepMind, Chongli studied in Cambridge, where she studied the mathematics tripos and scientific computing before doing a PhD in bioinformatics.
Iason Gabriel is a Senior Research Scientist at DeepMind where he works in the ethics research team. His work focuses on the applied ethics of artificial intelligence, human rights, and the question of how to align technology with human values. Before joining DeepMind, Iason was a Fellow in Politics at St John’s College, Oxford, and a member of the Centre for the Study of Social Justice (CSSJ). He holds a doctorate in Political Theory from the University of Oxford and spent a number of years working for the United Nations in post-conflict environments.
About the lecture series:
The Deep Learning Lecture Series is a collaboration between DeepMind and the UCL Centre for Artificial Intelligence. Over the past decade, Deep Learning has evolved as the leading artificial intelligence paradigm providing us with the ability to learn complex functions from raw data at unprecedented accuracy and scale. Deep Learning has been applied to problems in object recognition, speech recognition, speech synthesis, forecasting, scientific computing, control and many more. The resulting applications are touching all of our lives in areas such as healthcare and medical research, human-computer interaction, communication, transport, conservation, manufacturing and many other fields of human endeavour. In recognition of this huge impact, the 2019 Turing Award, the highest honour in computing, was awarded to pioneers of Deep Learning.
In this lecture series, research scientists from leading AI research lab, DeepMind, deliver 12 lectures on an exciting selection of topics in Deep Learning, ranging from the fundamentals of training neural networks via advanced ideas around memory, attention, and generative modelling to the important topic of responsible innovation.