The Company of Biologists | Z-stack through mouse kidney expressing activated NOTCH @CompanyofBiologists | Uploaded June 2022 | Updated October 2024, 1 day ago.
In Issue 10, Kathryn Duvall, Raphael Kopan and colleagues examine the role of Notch in nephron segmentation using the developing mouse kidney and human kidney organoids. Our featured movie is a Z-stack through a mouse kidney expressing activated NOTCH; labelled with antibodies against Wt1 (NPC and podocyte marker), Tfap2b (distal tubule marker) and Hnf4a and LTL (proximal tubule markers).

journals.biologists.com/dev/article/149/10/dev200446/275412/Revisiting-the-role-of-Notch-in-nephron

journals.biologists.com/dev/issue/149/10