Uploaded July 2026 | Updated September 2026, 2 weeks ago
This week I'm joined by David Rock, neuroscientist, author and founder of the NeuroLeadership Institute, and someone who has spent 28 years answering one of the most fascinating questions in science:Why do we do what we do? And how can understanding our brain change everything?
We explore human behaviour, the neuroscience of threat and reward, and what it really means to work with your brain rather than against it.
Dr. David Rock coined the term neuroleadership and is the Co-founder and CEO of the NeuroLeadership Institute (NLI). The Institute is a 23-year-old cognitive science consultancy that has advised over 50% of the Fortune 100. With operations in 24 countries, the institute brings neuroscientists and leadership experts together to make organisations better for humans through science.
Dr. Rock has authored four successful books including Your Brain at Work, a business best-seller, and has written for and been quoted in hundreds of articles about leadership, organizational effectiveness, and the brain which can be found in Harvard Business Review, The New York Times, The Wall Street Journal, Business Insider, CNBC, Forbes, Fortune, Inc., USA Today, BBC, The Boston Globe and more.
What we explore together:
•Why the brain is always making a threat or reward decision
•What the SCARF model is and why it explains almost every difficult human interaction
•Why being interrupted feels physically painful and what your brain is actually doing
•How insights really work in the brain and why your best ideas come when you stop trying
•Why one negative comment can override dozens of positive ones and how to rewire that
•What sleep, glucose and rest actually do to your ability to think clearly
•Why status is one of the most powerful forces driving human behaviour and how to work with it
Love, Sarah Ann 💛
My book 'Healthy Shouldn't Be This Hard': amazon.co.uk/Healthy-Shouldnt-Be-This-Hard-ebook/dp/B0G1DHNRV5
This episode is sponsored by:
NOWATCH: The compassionate health tracker Connecting body and mind with unique stress recovery insights so you can live fully today
👉 15% off with code LWBW15 at nowatch.com
The Great British Veg Out
How to support your gut, energy, and hormones by eating more — not less.
👉 https://sarahmacklin.substack.com/p/t…
Reset Your Health
If your body feels off after stress, travel, or burnout — this is where to start.
👉 https://sarahmacklin.substack.com/s/r...
👉 Practical beats perfect. Here's a free 5-recipe PDF I use to support energy and stress during busy weeks.
sarahannmacklin.com/5_free_recipes
👉 If this resonates, you can join the thousands who read The Compassionate Cure each week.
sarahmacklin.substack.com
Let's be friends!
📷 Instagram: instagram.com/sarahannmacklin
📹 Subscribe: youtube.com/@livewellbewellsarah
🐦 Twitter: https://x.com/SarahAnnMacklin
📱 TikTok: tiktok.com/@livewellbewellpodcast
💌 Newsletter: sarahmacklin.substack.com
Chapters
00:00 Introduction
02:55 How David discovered the brain's threat and reward system
06:08 Why we avoid bad things more than we seek good ones
09:00 What happens to your brain when you're overwhelmed
12:02 Brain fog — what it actually is and why it happens
14:58 The prefrontal cortex and why it matters so much
18:00 Why being interrupted is so disruptive to the brain
20:54 The difference between direct experience and narrative thinking
23:49 How to shift your brain into a better state
27:02 The science of insight — where great ideas really come from
29:47 Why your best thinking happens away from your desk
33:02 How much information the brain can actually handle
36:02 The negativity bias — why bad news hits harder than good
38:57 One negative comment vs dozens of positive ones
42:08 What happens in the brain when someone fails
44:58 How to spot where your attention really goes
47:57 Why rest is not optional for a high performing brain
51:08 Sleep, glucose and what they really do to your thinking
54:06 When you can't switch off — what the brain needs
57:07 Why doing nothing feels so hard — and why it matters
60:00 The SCARF model — status, certainty, autonomy, relatedness, fairness
62:52 Why inequality triggers such a strong brain response
66:04 The neuroscience of emotion and why it matters
69:08 Humour, connection and the brain
72:00 What a level five insight actually feels like
75:02 Why the SCARF model resonates with so many people
77:59 The five levels of insight explained
81:07 How to create the conditions for more insights
83:53 The law of decreasing returns on thinking
87:08 Running a business for 28 years — what David has learned
89:57 Final thoughts on working with your brain
This week I'm joined by David Rock, neuroscientist, author and founder of the NeuroLeadership Institute, and someone who has spent 28 years answering one of the most fascinating questions in science:Why do we do what we do? And how can understanding our brain change everything?
We explore human behaviour, the neuroscience of threat and reward, and what it really means to work with your brain rather than against it.
Dr. David Rock coined the term neuroleadership and is the Co-founder and CEO of the NeuroLeadership Institute (NLI). The Institute is a 23-year-old cognitive science consultancy that has advised over 50% of the Fortune 100. With operations in 24 countries, the institute brings neuroscientists and leadership experts together to make organisations better for humans through science.
Dr. Rock has authored four successful books including Your Brain at Work, a business best-seller, and has written for and been quoted in hundreds of articles about leadership, organizational effectiveness, and the brain which can be found in Harvard Business Review, The New York Times, The Wall Street Journal, Business Insider, CNBC, Forbes, Fortune, Inc., USA Today, BBC, The Boston Globe and more.
What we explore together:
•Why the brain is always making a threat or reward decision
•What the SCARF model is and why it explains almost every difficult human interaction
•Why being interrupted feels physically painful and what your brain is actually doing
•How insights really work in the brain and why your best ideas come when you stop trying
•Why one negative comment can override dozens of positive ones and how to rewire that
•What sleep, glucose and rest actually do to your ability to think clearly
•Why status is one of the most powerful forces driving human behaviour and how to work with it
Love, Sarah Ann 💛
My book 'Healthy Shouldn't Be This Hard': amazon.co.uk/Healthy-Shouldnt-Be-This-Hard-ebook/dp/B0G1DHNRV5
This episode is sponsored by:
NOWATCH: The compassionate health tracker Connecting body and mind with unique stress recovery insights so you can live fully today
👉 15% off with code LWBW15 at nowatch.com
The Great British Veg Out
How to support your gut, energy, and hormones by eating more — not less.
👉 https://sarahmacklin.substack.com/p/t…
Reset Your Health
If your body feels off after stress, travel, or burnout — this is where to start.
👉 https://sarahmacklin.substack.com/s/r...
👉 Practical beats perfect. Here's a free 5-recipe PDF I use to support energy and stress during busy weeks.
sarahannmacklin.com/5_free_recipes
👉 If this resonates, you can join the thousands who read The Compassionate Cure each week.
sarahmacklin.substack.com
Let's be friends!
📷 Instagram: instagram.com/sarahannmacklin
📹 Subscribe: youtube.com/@livewellbewellsarah
🐦 Twitter: https://x.com/SarahAnnMacklin
📱 TikTok: tiktok.com/@livewellbewellpodcast
💌 Newsletter: sarahmacklin.substack.com
Chapters
00:00 Introduction
02:55 How David discovered the brain's threat and reward system
06:08 Why we avoid bad things more than we seek good ones
09:00 What happens to your brain when you're overwhelmed
12:02 Brain fog — what it actually is and why it happens
14:58 The prefrontal cortex and why it matters so much
18:00 Why being interrupted is so disruptive to the brain
20:54 The difference between direct experience and narrative thinking
23:49 How to shift your brain into a better state
27:02 The science of insight — where great ideas really come from
29:47 Why your best thinking happens away from your desk
33:02 How much information the brain can actually handle
36:02 The negativity bias — why bad news hits harder than good
38:57 One negative comment vs dozens of positive ones
42:08 What happens in the brain when someone fails
44:58 How to spot where your attention really goes
47:57 Why rest is not optional for a high performing brain
51:08 Sleep, glucose and what they really do to your thinking
54:06 When you can't switch off — what the brain needs
57:07 Why doing nothing feels so hard — and why it matters
60:00 The SCARF model — status, certainty, autonomy, relatedness, fairness
62:52 Why inequality triggers such a strong brain response
66:04 The neuroscience of emotion and why it matters
69:08 Humour, connection and the brain
72:00 What a level five insight actually feels like
75:02 Why the SCARF model resonates with so many people
77:59 The five levels of insight explained
81:07 How to create the conditions for more insights
83:53 The law of decreasing returns on thinking
87:08 Running a business for 28 years — what David has learned
89:57 Final thoughts on working with your brain









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What happens when one unelected individual holds extraordinary influence over global health decisions — does good intent make it acceptable? And if accountability structures are the real safeguard against human fallibility, why do we keep building systems without them?
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This episode is sponsored by:
NOWATCH: The compassionate health tracker
Connecting body and mind with unique stress recovery insights so you can live fully today
15% off with code LWBW15 at https://nowatch.com/
Mojo: the app for expert-led courses in better sex.
Learn from world-class sex therapists and relationship experts with courses tailored to your needs.
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***
The Great British Veg Out
How to support your gut, energy, and hormones by eating more — not less.
👉 https://sarahmacklin.substack.com/p/the-great-british-veg-out
Reset Your Health
If your body feels off after stress, travel, or burnout — this is where to start.
👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days
👉 Practical beats perfect.
Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.
https://sarahannmacklin.com/5_free_recipes
👉 If this resonates, you can join the thousands who read
The Compassionate Cure each week.
https://sarahmacklin.substack.com/
***
Let’s be friends!
📷 Instagram: https://www.instagram.com/sarahannmacklin/
📹 Subscribe: http://www.youtube.com/@livewellbewellsarah
🐦 Twitter: https://x.com/SarahAnnMacklin
📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast
💌 Newsletter: https://sarahmacklin.substack.com/ Bill Gates Saves Lives But At What Cost? [Explained] | Dr Gemma Newman](https://i.ytimg.com/vi/jubSo2eS39A/mqdefault.jpg)
