Uploaded May 2026 | Updated September 2026, 2 weeks ago
Your body makes creatine. So why isn't that enough?
Watch the full video: youtu.be/C7vSAN-TGEE
Dr. Dan Pardi explains how creatine is synthesized (starting in the kidneys, completed in the liver), why dietary sources are almost entirely animal-based, and what that means for the growing number of women eating less red meat — or none at all.
We also get into the hunter-gatherer angle: estimates suggest our ancestors were consuming 5–10 grams of creatine per day through diet alone. Most people today are getting a fraction of that. Which means what we call a "normal" baseline might already be a deficit.
And yes — women synthesize about 20–30% less creatine than men. Not because of diet alone. Because of hormones. Estrogen upregulates the entire creatine system. Perimenopause and menopause change the equation in ways most women have never been told about.
What you'll learn:
→ How your body makes creatine (and where it goes from there)
→ Why vegans and vegetarians are likely running a persistent deficit
→ The hunter-gatherer creatine intake estimate and what it implies
→ Who probably doesn't need to supplement daily — and when they might still benefit
→ Why women synthesize less, age-related declines, and the case for supplementation in midlife
→ The estrogen-creatine connection: why everything in the luteal phase feels harder
Dr. Dan Pardi is a sleep researcher, neuroscientist, and Chief Health Officer at Qualia Life.
#creatine #womenshealth #perimenopause #hormones #supplementation #betterwithstephanie
Your body makes creatine. So why isn't that enough?
Watch the full video: youtu.be/C7vSAN-TGEE
Dr. Dan Pardi explains how creatine is synthesized (starting in the kidneys, completed in the liver), why dietary sources are almost entirely animal-based, and what that means for the growing number of women eating less red meat — or none at all.
We also get into the hunter-gatherer angle: estimates suggest our ancestors were consuming 5–10 grams of creatine per day through diet alone. Most people today are getting a fraction of that. Which means what we call a "normal" baseline might already be a deficit.
And yes — women synthesize about 20–30% less creatine than men. Not because of diet alone. Because of hormones. Estrogen upregulates the entire creatine system. Perimenopause and menopause change the equation in ways most women have never been told about.
What you'll learn:
→ How your body makes creatine (and where it goes from there)
→ Why vegans and vegetarians are likely running a persistent deficit
→ The hunter-gatherer creatine intake estimate and what it implies
→ Who probably doesn't need to supplement daily — and when they might still benefit
→ Why women synthesize less, age-related declines, and the case for supplementation in midlife
→ The estrogen-creatine connection: why everything in the luteal phase feels harder
Dr. Dan Pardi is a sleep researcher, neuroscientist, and Chief Health Officer at Qualia Life.
#creatine #womenshealth #perimenopause #hormones #supplementation #betterwithstephanie
