Uploaded November 2025 | Updated September 2026, 2 weeks ago
Subscribe to our channel: youtube.com/@matt.kaeberlein
Get Our Newsletter (It's Free): https://www.optispan.life/
Joel Jamieson is back for another deep dive, and this episode is packed with actionable insights, personal health revelations, and answers to your burning questions. We cover everything from the legitimacy of new health tech to Joel's ongoing journey with a shocking calcium score and what he's doing about it.
If you have a family history of heart disease, use wearable tech, or are just focused on optimizing your health and longevity, this conversation is for you.
This video was produced by One Billion Media, an agency that specializes in YouTube virality for health brands and experts. Learn more about their work here:
onebillionmedia.com
TIMESTAMPS:
00:00:00 - Introduction & The Random Test
00:01:38 - The Quest Bar Founder Funding Cancer Research
00:02:47 - New AirPods & Measuring Heart Rate/HRV Through Your Ear
00:05:04 - HRV: Training to Win vs. Training for Longevity
00:06:09 - Waking Up at 4:30 AM vs. 6:30 AM: Impact on Sleep & HRV
00:09:45 - ADHD Medications, Supplements, and Their Effects on HRV
00:10:56 - The Search for Large-Scale HRV Data
00:11:56 - Is HRV Still "Cutting Edge"?
00:13:38 - What's Better Than HRV? (The "Dream" Biomarker)
00:14:59 - Can You Measure HRV Without a Smart Device?
00:15:53 - Cannabis Use and Its Drastic Impact on HRV
00:17:59 - Best Practices for Accurate HRV Measurement (Morpheus)
00:18:52 - DEEP DIVE: Joel's Shocking Heart Health Journey
00:29:07 - Listener Case: High LP(a) and Stubbornly Low HRV
00:30:36 - Listener Case: Low Oura Ring HRV but Excellent Other Markers
00:32:56 - The Problem with "Cardiovascular Age" Metrics
00:34:11 - How Accurate Are Garmin & Oura Ring VO2 Max Estimates?
00:37:51 - The Credibility Problem with "Biological Age" & Oral Peptides
00:40:07 - Update: Joel's Latest CCTA & Calcium Score Results
00:41:32 - Analyzing the Scans: Radiologist vs. Cleerly AI
If you have a family history of heart disease, this conversation is a must-watch. Listen to the full podcast now.
If you enjoyed this don’t forget to subscribe and hit the bell so you don’t miss our next deep-dive conversation.
Learn More: 8weeksout.com
Follow Joel on Instagram: instagram.com/coachjoeljamieson
DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.
More places to find us:
Twitter: https://x.com/Optispan_Inc
Twitter: twitter.com/mkaeberlein
Linkedin: linkedin.com/company/optispan
Instagram: instagram.com/optispan_
TikTok: tiktok.com/@optispan
https://www.optispan.life/
Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.
On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!
Subscribe to our channel: youtube.com/@matt.kaeberlein
Get Our Newsletter (It's Free): https://www.optispan.life/
Joel Jamieson is back for another deep dive, and this episode is packed with actionable insights, personal health revelations, and answers to your burning questions. We cover everything from the legitimacy of new health tech to Joel's ongoing journey with a shocking calcium score and what he's doing about it.
If you have a family history of heart disease, use wearable tech, or are just focused on optimizing your health and longevity, this conversation is for you.
This video was produced by One Billion Media, an agency that specializes in YouTube virality for health brands and experts. Learn more about their work here:
onebillionmedia.com
TIMESTAMPS:
00:00:00 - Introduction & The Random Test
00:01:38 - The Quest Bar Founder Funding Cancer Research
00:02:47 - New AirPods & Measuring Heart Rate/HRV Through Your Ear
00:05:04 - HRV: Training to Win vs. Training for Longevity
00:06:09 - Waking Up at 4:30 AM vs. 6:30 AM: Impact on Sleep & HRV
00:09:45 - ADHD Medications, Supplements, and Their Effects on HRV
00:10:56 - The Search for Large-Scale HRV Data
00:11:56 - Is HRV Still "Cutting Edge"?
00:13:38 - What's Better Than HRV? (The "Dream" Biomarker)
00:14:59 - Can You Measure HRV Without a Smart Device?
00:15:53 - Cannabis Use and Its Drastic Impact on HRV
00:17:59 - Best Practices for Accurate HRV Measurement (Morpheus)
00:18:52 - DEEP DIVE: Joel's Shocking Heart Health Journey
00:29:07 - Listener Case: High LP(a) and Stubbornly Low HRV
00:30:36 - Listener Case: Low Oura Ring HRV but Excellent Other Markers
00:32:56 - The Problem with "Cardiovascular Age" Metrics
00:34:11 - How Accurate Are Garmin & Oura Ring VO2 Max Estimates?
00:37:51 - The Credibility Problem with "Biological Age" & Oral Peptides
00:40:07 - Update: Joel's Latest CCTA & Calcium Score Results
00:41:32 - Analyzing the Scans: Radiologist vs. Cleerly AI
If you have a family history of heart disease, this conversation is a must-watch. Listen to the full podcast now.
If you enjoyed this don’t forget to subscribe and hit the bell so you don’t miss our next deep-dive conversation.
Learn More: 8weeksout.com
Follow Joel on Instagram: instagram.com/coachjoeljamieson
DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.
More places to find us:
Twitter: https://x.com/Optispan_Inc
Twitter: twitter.com/mkaeberlein
Linkedin: linkedin.com/company/optispan
Instagram: instagram.com/optispan_
TikTok: tiktok.com/@optispan
https://www.optispan.life/
Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.
On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!
