Uploaded April 2026 | Updated September 2026, 2 weeks ago
This Week In Startups is made possible by:
Quo - quo.com/TWiST
Vanta - vanta.com/twist
Pilot - pilot.com/twist
Plaud - Plaud.ai/twist
Today’s show:
Eragon CEO Josh Sirota believes that you should “own your intelligence.” He demos a live enterprise AI operating system connecting email, Slack, calendar, and financial data into a single agentic layer that’s pre-trained to understand any business inside and out.
PLUS we’ve got IONA Drones founder Etienne Louvet, a first look at Moonshot’s Kimi K2.6, and a brand new Off Duty with JCal and Lon.
FULL SHOW NOTES ON NOTION: https://thisweekinstartups-docket.notion.site/TWiST-2278-SHOW-NOTES-34872ca918e380bd9c71e684ce2db7c9?source=copy_link
Guests :
Eragon: eragon.ai
Josh Sirota on X: https://x.com/joshua_sirota
IONA: ionadrones.com
Etienne Louvet on X: https://x.com/etienneldva
Relevant Links:
Eragon Seed Round coverage: techcrunch.com/2026/03/18/this-startup-wants-to-make-enterprise-software-look-more-like-a-prompt
Neurometric: neurometric.ai
Ollama model: ollama.com
Orange Slice: orangeslice.ai
Corgi Insurance: https://www.corgi.insure/
Slash Financial: slash.com
The Syndicate: thesyndicate.com
FAA Part 108 Explained: pilotinstitute.com/part-108-explained
Zipline: zipline.com
Google Wing: wing.com
Joby Aviation: jobyaviation.com
Enterprise Ireland: enterprise-ireland.com
Éire Composites: eirecomposites.com
Kimi K2.6 blog post: kimi.com/blog/kimi-k2-6
Kimi K2 series on GitHub: github.com/moonshotai/Kimi-K2
NVIDIA GB300 NVL72 work station: nvidia.com/en-us/data-center/gb300-nvl72
Breakthrough Prize: breakthroughprize.org
ACME AI & FX: acmeai.com
“Bitcoin: Killing Satoshi” press coverage: gizmodo.com/hollywoods-first-big-budget-ai-generated-movie-is-about-bitcoin-of-course-2000747573
Off Duty Recommendations:
Kurosawa’s “Ikiru”: youtube.com/watch?v=2VeLN3IDjzQ
2022 “Ikiru” remake “Living”: youtube.com/watch?v=OVo5kLt_-BU
FX’s “Love Story: John F. Kennedy Jr. & Carolyn Bessette”: youtube.com/watch?v=Gw2RakWShdE
“Dust Bunny” trailer: youtube.com/watch?v=lQqmOjPDlWg
Wild Planet tinned fish: wildplanetfoods.com
Timestamps:
0:00 Josh from Eragon AI joins the show
1:18 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at Plaud.ai/twist and use code TWIST for 10% off!
4:24 Why founders should own and control their data sets
7:50 What is a "company world model?"
9:05 Quo (formerly OpenPhone) - Quo gives you a clean, modern way to handle every customer call, text, and thread all in one place. Try it free at quo.com/TWiST
10:49 Eragon demo
15:12 Giving agents their own bank accounts
18:24 Inside Eragon's first partnerships
19:31 Vanta - Get $1000 off your SOC 2 at vanta.com/twist
25:07 How does Eragon make money?
28:28 Pilot - Visit pilot.com/twist and get $1,200 off your first year.
38:50 Etienne Louvet of Iona Drones joins the show
41:54 What is FAA's Part 108?
46:30 How innovation in drones impacts the aviation industry
49:43 Working with Enterprise Ireland
57:45 Jason attended the Breakthrough Awards
1:03:27 Doug Liman's AI-powered "Bitcoin" movie
1:08:26 "Love Story" on FX and "Dust Bunny" on HBO Max
1:12:27 Jason's love of tinned fish
Subscribe to the TWiST500 newsletter: ticker.thisweekinstartups.com
Check out the TWIST500: twist500.com
Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp
Follow Lon:
X: https://x.com/lons
Follow Alex:
X: https://x.com/alex
LinkedIn: linkedin.com/in/alexwilhelm
Follow Jason:
X: twitter.com/Jason
LinkedIn: linkedin.com/in/jasoncalacanis
Check out all our partner offers: partners.launch.co
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
Check out Jason’s suite of newsletters: substack.com/@calacanis
Follow TWiST:
Twitter: twitter.com/TWiStartups
YouTube: youtube.com/thisweekin
Instagram: instagram.com/thisweekinstartups
TikTok: tiktok.com/@thisweekinstartups
Substack: twistartups.substack.com
This Week In Startups is made possible by:
Quo - quo.com/TWiST
Vanta - vanta.com/twist
Pilot - pilot.com/twist
Plaud - Plaud.ai/twist
Today’s show:
Eragon CEO Josh Sirota believes that you should “own your intelligence.” He demos a live enterprise AI operating system connecting email, Slack, calendar, and financial data into a single agentic layer that’s pre-trained to understand any business inside and out.
PLUS we’ve got IONA Drones founder Etienne Louvet, a first look at Moonshot’s Kimi K2.6, and a brand new Off Duty with JCal and Lon.
FULL SHOW NOTES ON NOTION: https://thisweekinstartups-docket.notion.site/TWiST-2278-SHOW-NOTES-34872ca918e380bd9c71e684ce2db7c9?source=copy_link
Guests :
Eragon: eragon.ai
Josh Sirota on X: https://x.com/joshua_sirota
IONA: ionadrones.com
Etienne Louvet on X: https://x.com/etienneldva
Relevant Links:
Eragon Seed Round coverage: techcrunch.com/2026/03/18/this-startup-wants-to-make-enterprise-software-look-more-like-a-prompt
Neurometric: neurometric.ai
Ollama model: ollama.com
Orange Slice: orangeslice.ai
Corgi Insurance: https://www.corgi.insure/
Slash Financial: slash.com
The Syndicate: thesyndicate.com
FAA Part 108 Explained: pilotinstitute.com/part-108-explained
Zipline: zipline.com
Google Wing: wing.com
Joby Aviation: jobyaviation.com
Enterprise Ireland: enterprise-ireland.com
Éire Composites: eirecomposites.com
Kimi K2.6 blog post: kimi.com/blog/kimi-k2-6
Kimi K2 series on GitHub: github.com/moonshotai/Kimi-K2
NVIDIA GB300 NVL72 work station: nvidia.com/en-us/data-center/gb300-nvl72
Breakthrough Prize: breakthroughprize.org
ACME AI & FX: acmeai.com
“Bitcoin: Killing Satoshi” press coverage: gizmodo.com/hollywoods-first-big-budget-ai-generated-movie-is-about-bitcoin-of-course-2000747573
Off Duty Recommendations:
Kurosawa’s “Ikiru”: youtube.com/watch?v=2VeLN3IDjzQ
2022 “Ikiru” remake “Living”: youtube.com/watch?v=OVo5kLt_-BU
FX’s “Love Story: John F. Kennedy Jr. & Carolyn Bessette”: youtube.com/watch?v=Gw2RakWShdE
“Dust Bunny” trailer: youtube.com/watch?v=lQqmOjPDlWg
Wild Planet tinned fish: wildplanetfoods.com
Timestamps:
0:00 Josh from Eragon AI joins the show
1:18 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at Plaud.ai/twist and use code TWIST for 10% off!
4:24 Why founders should own and control their data sets
7:50 What is a "company world model?"
9:05 Quo (formerly OpenPhone) - Quo gives you a clean, modern way to handle every customer call, text, and thread all in one place. Try it free at quo.com/TWiST
10:49 Eragon demo
15:12 Giving agents their own bank accounts
18:24 Inside Eragon's first partnerships
19:31 Vanta - Get $1000 off your SOC 2 at vanta.com/twist
25:07 How does Eragon make money?
28:28 Pilot - Visit pilot.com/twist and get $1,200 off your first year.
38:50 Etienne Louvet of Iona Drones joins the show
41:54 What is FAA's Part 108?
46:30 How innovation in drones impacts the aviation industry
49:43 Working with Enterprise Ireland
57:45 Jason attended the Breakthrough Awards
1:03:27 Doug Liman's AI-powered "Bitcoin" movie
1:08:26 "Love Story" on FX and "Dust Bunny" on HBO Max
1:12:27 Jason's love of tinned fish
Subscribe to the TWiST500 newsletter: ticker.thisweekinstartups.com
Check out the TWIST500: twist500.com
Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp
Follow Lon:
X: https://x.com/lons
Follow Alex:
X: https://x.com/alex
LinkedIn: linkedin.com/in/alexwilhelm
Follow Jason:
X: twitter.com/Jason
LinkedIn: linkedin.com/in/jasoncalacanis
Check out all our partner offers: partners.launch.co
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
Check out Jason’s suite of newsletters: substack.com/@calacanis
Follow TWiST:
Twitter: twitter.com/TWiStartups
YouTube: youtube.com/thisweekin
Instagram: instagram.com/thisweekinstartups
TikTok: tiktok.com/@thisweekinstartups
Substack: twistartups.substack.com
