The Sheekey Science Show | Why do reindeer antlers regenerate? @TheSheekeyScienceShow | Uploaded 1 year ago | Updated 3 hours ago
Different organisms respond differently to injury. Axolotls can regenerate entire limbs, planaria can regrow heads from a single cell. But if we get even a small skin wounds as adults, like most other adult mammalian tissue, we get scars, not regeneration of the tissue.
But why? How come some tissues can regenerate, while others form scar tissue? How is that decision mediated & why ultimately would it be useful to have this information? Well, that brings us to the item on my head.
Reindeer, also known as caribou, are known for their distinctive antlers, like the ones on my head, that are covered in a soft, velvety skin, which are used for fighting, mating, and display. The interesting point of relevance for this video is that reindeer antlers also have the ability to regenerate after being damaged or broken? In this video, we will talk through this latest paper about reindeer, regeneration and wound response.
#SheekeySleighs #reindeer #regeneration
Find me on Twitter - https://twitter.com/EleanorSheekey
Support the channel
through PayPal - https://paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB
through Patreon - https://www.patreon.com/TheSheekeyScienceShow
TIMESTAMPS
Intro - 00:00
Regeneration of antler velvet - 01:00
Wound response - 01:30
Molecular mechanism - 03:00
Senescence & open questions - 05:40
References
Fibroblast inflammatory priming determines regenerative versus fibrotic skin repair in reindeer - https://doi.org/10.1016/j.cell.2022.11.004
Reindeer light the way to scarless wound healing - https://doi.org/10.1016/j.cell.2022.11.013
Gurtner, G., Werner, S., Barrandon, Y. et al. Wound repair and regeneration. Nature 453, 314–321 (2008). https://doi.org/10.1038/nature07039
Wound repair and regeneration: Mechanisms, signaling, and translation - https://doi.org/10.1126/scitranslmed.3009337
Please note that The Sheekey Science Show is distinct from Eleanor Sheekey's teaching and research roles at the University of Cambridge. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.
Icons in intro; "https://www.freepik.com/free-photos-vectors/background"Background vector created by freepik - www.freepik.com
Different organisms respond differently to injury. Axolotls can regenerate entire limbs, planaria can regrow heads from a single cell. But if we get even a small skin wounds as adults, like most other adult mammalian tissue, we get scars, not regeneration of the tissue.
But why? How come some tissues can regenerate, while others form scar tissue? How is that decision mediated & why ultimately would it be useful to have this information? Well, that brings us to the item on my head.
Reindeer, also known as caribou, are known for their distinctive antlers, like the ones on my head, that are covered in a soft, velvety skin, which are used for fighting, mating, and display. The interesting point of relevance for this video is that reindeer antlers also have the ability to regenerate after being damaged or broken? In this video, we will talk through this latest paper about reindeer, regeneration and wound response.
#SheekeySleighs #reindeer #regeneration
Find me on Twitter - https://twitter.com/EleanorSheekey
Support the channel
through PayPal - https://paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB
through Patreon - https://www.patreon.com/TheSheekeyScienceShow
TIMESTAMPS
Intro - 00:00
Regeneration of antler velvet - 01:00
Wound response - 01:30
Molecular mechanism - 03:00
Senescence & open questions - 05:40
References
Fibroblast inflammatory priming determines regenerative versus fibrotic skin repair in reindeer - https://doi.org/10.1016/j.cell.2022.11.004
Reindeer light the way to scarless wound healing - https://doi.org/10.1016/j.cell.2022.11.013
Gurtner, G., Werner, S., Barrandon, Y. et al. Wound repair and regeneration. Nature 453, 314–321 (2008). https://doi.org/10.1038/nature07039
Wound repair and regeneration: Mechanisms, signaling, and translation - https://doi.org/10.1126/scitranslmed.3009337
Please note that The Sheekey Science Show is distinct from Eleanor Sheekey's teaching and research roles at the University of Cambridge. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.
Icons in intro; "https://www.freepik.com/free-photos-vectors/background"Background vector created by freepik - www.freepik.com
