Uploaded September 2025 | Updated September 2026, 2 weeks ago
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0:51 What is Pluvicto and when is it used?
2:46 What kind of PSA decline would indicate that Pluvicto is working?
4:20 Can you only determine effectiveness after a treatment course ends?
6:41 Is Pluvicto generally ineffective in a third of patients?
7:51 If Pluvicto isn't working, what's the next best option?
9:23 Should patients ever advocate for other treatments before a Pluvicto course ends?
9:55 What is the usual sequence of options after Pluvicto?
11:26 Is chemotherapy a common next step after Pluvicto?
13:27 Is Xofigo a good stopgap while waiting to get other treatments?
15:29 Is Xofigo an advisable route to take if Pluvicto isn't working?
17:14 Alex's conclusions
Don't know your stage? Take the quiz: visit prostatecancerstaging.org
To learn more about prostate cancer, visit pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Learn more about Pluvicto here: us.pluvicto.com
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Donate to PCRI: pcri.org/donate
For more information, visit pcri.org
0:51 What is Pluvicto and when is it used?
2:46 What kind of PSA decline would indicate that Pluvicto is working?
4:20 Can you only determine effectiveness after a treatment course ends?
6:41 Is Pluvicto generally ineffective in a third of patients?
7:51 If Pluvicto isn't working, what's the next best option?
9:23 Should patients ever advocate for other treatments before a Pluvicto course ends?
9:55 What is the usual sequence of options after Pluvicto?
11:26 Is chemotherapy a common next step after Pluvicto?
13:27 Is Xofigo a good stopgap while waiting to get other treatments?
15:29 Is Xofigo an advisable route to take if Pluvicto isn't working?
17:14 Alex's conclusions
Don't know your stage? Take the quiz: visit prostatecancerstaging.org
To learn more about prostate cancer, visit pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Learn more about Pluvicto here: us.pluvicto.com
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
