The Company of Biologists | Unipotent progenitors (UHCP) dividing into two hair cells. @CompanyofBiologists | Uploaded May 2023 | Updated October 2024, 7 hours ago.
In Volume 150, Issue 9 of Development, Eva L. Kozak, Jerónimo R. Miranda-Rodríguez, Hernán López-Schier and colleagues uncovers a role for Notch1a-mediated symmetry breaking in stabilising cell rotation.
This highlighted video shows a wild-type horizontal neuromast with a focus on a dividing UHCP that results in a pair of nascent hair cells inverting. Membranes are marked by the claudnb:lyn-EGFP transgenic. Hair cells are marked simultaneously by myo6b:β-actin-GFP that also allows us to see the orientation of their hair bundle.
In Volume 150, Issue 9 of Development, Eva L. Kozak, Jerónimo R. Miranda-Rodríguez, Hernán López-Schier and colleagues uncovers a role for Notch1a-mediated symmetry breaking in stabilising cell rotation.
This highlighted video shows a wild-type horizontal neuromast with a focus on a dividing UHCP that results in a pair of nascent hair cells inverting. Membranes are marked by the claudnb:lyn-EGFP transgenic. Hair cells are marked simultaneously by myo6b:β-actin-GFP that also allows us to see the orientation of their hair bundle.